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Fibroblast Growth Factor Receptor (FGFR)

Fibroblast Growth Factor Receptor (FGFR)

FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.

Found 170 products of "Fibroblast Growth Factor Receptor (FGFR)"

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  • LY2874455
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    LY2874455

    CAS:
    <p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>
    Formula:C21H19Cl2N5O2
    Purity:97.22% - 99.46%
    Color and Shape:Solid
    Molecular weight:444.31

    Ref: TM-T2361

  • Erdafitinib
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    Erdafitinib

    CAS:
    <p>Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.</p>
    Formula:C25H30N6O2
    Purity:97.00% - 99.07%
    Color and Shape:Solid
    Molecular weight:446.54

    Ref: TM-T3726

  • ASP5878
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    ASP5878

    CAS:
    <p>ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.</p>
    Formula:C18H19F2N5O4
    Purity:99.8% - 99.89%
    Color and Shape:Solid
    Molecular weight:407.37

    Ref: TM-T5473

  • AZD4547
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    AZD4547

    CAS:
    <p>AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.</p>
    Formula:C26H33N5O3
    Purity:99.37% - 99.88%
    Color and Shape:Solid
    Molecular weight:463.57

    Ref: TM-T1948

  • CHIR-98014
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    CHIR-98014

    CAS:
    <p>CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.</p>
    Formula:C20H17Cl2N9O2
    Purity:97.25% - 99.59%
    Color and Shape:Solid
    Molecular weight:486.31

    Ref: TM-T2608

  • PD173074
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    PD173074

    CAS:
    <p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>
    Formula:C28H41N7O3
    Purity:98.15% - 98.21%
    Color and Shape:Yellow Solid
    Molecular weight:523.67

    Ref: TM-T2642

  • SU 5402
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    SU 5402

    CAS:
    <p>SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.</p>
    Formula:C17H16N2O3
    Purity:98.91% - 99.64%
    Color and Shape:Yellow-Green Solid
    Molecular weight:296.32

    Ref: TM-T6996

  • FGFR4-IN-1
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    FGFR4-IN-1

    CAS:
    <p>FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).</p>
    Formula:C24H27N7O5
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:493.52

    Ref: TM-TQ0256

  • PD-161570
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    PD-161570

    CAS:
    <p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>
    Formula:C26H35Cl2N7O
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:532.51

    Ref: TM-T23127

  • SUN11602
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    SUN11602

    CAS:
    <p>SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.</p>
    Formula:C26H37N5O2
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:451.6

    Ref: TM-T3714

  • Orantinib
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    Orantinib

    CAS:
    <p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>
    Formula:C18H18N2O3
    Purity:98.92% - 99.52%
    Color and Shape:Solid
    Molecular weight:310.35

    Ref: TM-T6184

  • Dovitinib
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    Dovitinib

    CAS:
    <p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>
    Formula:C21H21FN6O
    Purity:99.35% - 99.92%
    Color and Shape:Solid
    Molecular weight:392.43

    Ref: TM-T6289

  • XL 999
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    XL 999

    CAS:
    <p>Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）</p>
    Formula:C26H28FN5O
    Purity:98.24% - 99.55%
    Color and Shape:Solid
    Molecular weight:445.53

    Ref: TM-T5466

  • Zoligratinib
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    Zoligratinib

    CAS:
    <p>Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.</p>
    Formula:C20H16N6O
    Purity:95.28% - 99.51%
    Color and Shape:Solid
    Molecular weight:356.38

    Ref: TM-T6024

  • Infigratinib
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    Infigratinib

    CAS:
    <p>Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), &gt;40-fold selective for FGFR versus FGFR4 and</p>
    Formula:C26H31Cl2N7O3
    Purity:98% - 98.97%
    Color and Shape:Solid
    Molecular weight:560.48

    Ref: TM-T1975

  • DGY-06-116
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    DGY-06-116

    CAS:
    <p>DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.</p>
    Formula:C32H33ClN8O2
    Purity:97.65%
    Color and Shape:Solid
    Molecular weight:597.11

    Ref: TM-T22306

  • PF 477736
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    PF 477736

    CAS:
    <p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>
    Formula:C22H25N7O2
    Purity:97.58% - 99.94%
    Color and Shape:Solid
    Molecular weight:419.48

    Ref: TM-T6028

  • ENMD-2076
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    ENMD-2076

    CAS:
    <p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>
    Formula:C21H25N7
    Purity:97.63% - ≥95%
    Color and Shape:Solid
    Molecular weight:375.47

    Ref: TM-T2358

  • Regorafenib
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    Regorafenib

    CAS:
    <p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>
    Formula:C21H15ClF4N4O3
    Purity:98% - 99.95%
    Color and Shape:Solid
    Molecular weight:482.82

    Ref: TM-T1792

  • Masitinib
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    Masitinib

    CAS:
    <p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>
    Formula:C28H30N6OS
    Purity:97.56% - >99.99%
    Color and Shape:Solid
    Molecular weight:498.64

    Ref: TM-T2609