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Fibroblast Growth Factor Receptor (FGFR)

Fibroblast Growth Factor Receptor (FGFR)

FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.

Found 170 products of "Fibroblast Growth Factor Receptor (FGFR)"

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  • FGFR1 inhibitor-16
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    FGFR1 inhibitor-16

    CAS:
    <p>FGFR1inhibitor-16 (Compound 89) functions as an FGFR1 inhibitor, demonstrating an inhibition rate of 53.00% at a concentration of 50 μM and 24.95% at 10 μM. It is utilized in tumor research.</p>
    Formula:C16H9N5O3S
    Color and Shape:Solid
    Molecular weight:351.339

    Ref: TM-T205114

  • FGFR1 inhibitor-15
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    FGFR1 inhibitor-15

    CAS:
    <p>FGFR1inhibitor-15 (Compound 23) is an FGFR1 inhibitor with an IC50 value of 27 μM, useful for tumor research.</p>
    Formula:C17H13FN4O
    Color and Shape:Solid
    Molecular weight:308.31

    Ref: TM-T205729

  • FGFR2/3-IN-2
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    FGFR2/3-IN-2

    CAS:
    <p>FGFR2/3-IN-2 (compound 10) is an orally active inhibitor targeting FGFR2 and FGFR3. It exhibits IC50 values of 3.7 nM for FGFR2 and 31.2 nM for FGFR3, with a pre-incubation time of 1 hour. FGFR2/3-IN-2 demonstrates selectivity over FGFR1/4 and other kinases, and does not cause diarrhea or increased serum phosphate in vivo. In the SNU-16 gastric cancer model, FGFR2/3-IN-2 can induce tumor stasis or regression.</p>
    Formula:C29H23FN6O3
    Color and Shape:Solid
    Molecular weight:522.53

    Ref: TM-T205706

  • TYRA-300
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    TYRA-300

    CAS:
    <p>TYRA-300 is an oral and selective FGFR3 inhibito, in the Ba/F3 cell line for the treatment of metastatic uroepithelial carcinomas (mUCs) and chondrodysplasia.</p>
    Formula:C25H24Cl2N6O3S
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:559.47

    Ref: TM-T88841

  • FGFR-IN-16
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    FGFR-IN-16

    CAS:
    <p>FGFR-IN-16 (compound 7N) is a potent inhibitor of FGFR1, FGFR2, and FGFR4, exhibiting IC50 values of 8 nM, 4 nM, and 3.8 nM respectively. It plays a crucial role in cancer research.</p>
    Formula:C30H27Cl2N7O4
    Color and Shape:Solid
    Molecular weight:620.49

    Ref: TM-T201714

  • FGFR-IN-15
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    FGFR-IN-15

    <p>FGFR-IN-15 (compound 18i) acts as a pan-FGFR inhibitor, exhibiting potent inhibitory activity against FGFR1-4.</p>
    Formula:C22H23N5O5S
    Color and Shape:Solid
    Molecular weight:469.51

    Ref: TM-T201821

  • FGFR4-IN-4
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    FGFR4-IN-4

    CAS:
    <p>FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.</p>
    Formula:C28H32Cl2N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.5

    Ref: TM-T11280

  • PNU-145156E
    Targetmol
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    PNU-145156E

    CAS:
    <p>PNU-145156E is a noncytotoxic molecule inhibiting growth and angiogenic factors, suppress tumor angiogenesis, support anti-angiogenic research strategies.</p>
    Formula:C45H40N10O17S4
    Color and Shape:Solid
    Molecular weight:1121.12

    Ref: TM-T70412

  • Fanregratinib
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    Fanregratinib

    CAS:
    <p>Fanregratinib is a fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor.</p>
    Formula:C27H33ClN6O2
    Color and Shape:Solid
    Molecular weight:509.04

    Ref: TM-T201139

  • FGFR1 inhibitor-10
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    FGFR1 inhibitor-10

    CAS:
    <p>FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation.</p>
    Formula:C26H30F3N7O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:561.62

    Ref: TM-T79686

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