ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
Found 154 products for "ALK".
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LDN-193189 Tetrahydrochloride
CAS:LDN193189 is a BMPI receptor inhibitor, blocking ALK2 and ALK3 effectively, while weak on ALK4, ALK5, ALK7.Formula:C25H26Cl4N6Purity:98.21%Color and Shape:SolidMolecular weight:552.33RepSox
CAS:RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM).Formula:C17H13N5Purity:99.10% - 99.92%Color and Shape:Gray SolidMolecular weight:287.32Ref: TM-T6337
1mg34.00€2mg46.00€5mg63.00€1mL*10mM (DMSO)69.00€10mg80.00€25mg116.00€50mg169.00€100mg241.00€500mg597.00€GSK1838705A
CAS:GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.Formula:C27H29FN8O3Purity:98.89% - >99.99%Color and Shape:Yellow SolidMolecular weight:532.57Alectinib
CAS:Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.Formula:C30H34N4O2Purity:98% - 99.94%Color and Shape:White SolidMolecular weight:482.62Ref: TM-T1936
2mg44.00€5mg65.00€1mL*10mM (DMSO)70.00€10mg82.00€50mg100.00€100mg159.00€200mg245.00€500mg414.00€CEP-37440
CAS:CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).Formula:C30H38ClN7O3Purity:98.86% - 99.98%Color and Shape:White SolidMolecular weight:580.12Entrectinib
CAS:Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.Formula:C31H34F2N6O2Purity:98.03% - 99.67%Color and Shape:SolidMolecular weight:560.64Ref: TM-T3678
2mg39.00€5mg56.00€1mL*10mM (DMSO)65.00€10mg84.00€25mg105.00€50mg159.00€100mg268.00€500mg655.00€BIBF0775
CAS:BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).Formula:C31H34N4O2Purity:99.45% - 99.79%Color and Shape:SolidMolecular weight:494.63Ref: TM-T5197
1mg40.00€1mL*10mM (DMSO)90.00€5mg92.00€10mg128.00€25mg205.00€50mg288.00€100mg414.00€200mg578.00€LDN193189
CAS:LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.Formula:C25H22N6Purity:98% - 99.86%Color and Shape:SolidMolecular weight:406.48ML347
CAS:ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.Formula:C22H16N4OPurity:99.30% - ≥95%Color and Shape:SolidMolecular weight:352.39LDN-214117
CAS:LDN-214117 is a potent and selective ALK2 inhibitor.Formula:C25H29N3O3Purity:98% - 99.83%Color and Shape:SolidMolecular weight:419.52ALK5-IN-10
CAS:Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.Formula:C22H18BrN7Purity:99.93%Color and Shape:SolidMolecular weight:460.33AZD-3463
CAS:AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formula:C24H25ClN6OPurity:99.13% - 99.97%Color and Shape:Cyan SolidMolecular weight:448.95GW788388
CAS:GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.Formula:C25H23N5O2Purity:98.03% - 99.58%Color and Shape:SolidMolecular weight:425.48K02288
CAS:K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.Formula:C20H20N2O4Purity:98% - 99.83%Color and Shape:SolidMolecular weight:352.38CH5424802 analog
CAS:CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.Formula:C28H30N4O2Purity:98.96%Color and Shape:White SolidMolecular weight:454.56Ref: TM-T9224
1mg124.00€5mg271.00€1mL*10mM (DMSO)324.00€10mg408.00€25mg672.00€50mg945.00€100mg1,279.00€5-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.Formula:C12H9N3SPurity:97%Color and Shape:Yellow SolidMolecular weight:227.29Ref: TM-T50042
2mg43.00€5mg60.00€1mL*10mM (DMSO)60.00€10mg90.00€25mg138.00€50mg200.00€100mg301.00€200mg432.00€CAY10594
CAS:CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Formula:C26H28N4O2Purity:97.76%Color and Shape:White SolidMolecular weight:428.53Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formula:C21H23Cl3FN5OPurity:98.73% - 98.87%Color and Shape:SolidMolecular weight:486.8Ref: TM-T8399
5mg34.00€1mL*10mM (DMSO)35.00€10mg50.00€25mg78.00€50mg94.00€100mg131.00€200mg162.00€500mg215.00€DMH-1
CAS:DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.Formula:C24H20N4OPurity:98% - 99.92%Color and Shape:SolidMolecular weight:380.44Crizotinib
CAS:Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formula:C21H22Cl2FN5OPurity:99% - 99.87%Color and Shape:White SolidMolecular weight:450.34
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