ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
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GW788388
CAS:452342-67-5
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor …
Formula:
C25H23N5O2
Purity:
98.03% - 98.79%
Color and Shape:
Solid
Molecular weight:
425.48
Ref: TM-T1800
| 5mg | 64.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 266.00 € | ||
| 100mg | 393.00 € | ||
| 500mg | 914.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
ML347
CAS:1062368-49-3
ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the …
Formula:
C22H16N4O
Purity:
98.3% - ≥95%
Color and Shape:
Solid
Molecular weight:
352.39
Ref: TM-T1943
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 465.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
![5-phenylthieno[2,3-d]pyrimidin-4-amine](https://static.cymitquimica.com/products/TM/thumb/T50042.jpg)
5-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:195193-10-3
5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.
Formula:
C12H9N3S
Purity:
97%
Color and Shape:
Solid
Molecular weight:
227.29
Ref: TM-T50042
| 2mg | 46.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 319.00 € | ||
| 200mg | 455.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
RepSox
CAS:446859-33-2
RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP …
Formula:
C17H13N5
Purity:
98.8% - 99.62%
Color and Shape:
Solid
Molecular weight:
287.32
Ref: TM-T6337
| 1mg | 35.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 255.00 € | ||
| 500mg | 630.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SM 16
CAS:614749-78-9
SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).
Formula:
C25H26N4O3
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
430.5
Ref: TM-T4975
| 1mg | 46.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 264.00 € | ||
| 50mg | 427.00 € | ||
| 100mg | 630.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
![N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bro…](https://static.cymitquimica.com/products/TM/thumb/T9837.jpg)
N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
CAS:1352608-94-6
Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.
Formula:
C22H18BrN7
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
460.33
Ref: TM-T9837
| 1mg | 87.00 € | ||
| 5mg | 192.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 452.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 867.00 € | ||
| 200mg | 1,159.00 € | ||
| 1mL*10mM (DMSO) | 226.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
R-268712
CAS:879487-87-3
R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type …
Formula:
C20H18FN5O
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
363.39
Ref: TM-T16708
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 264.00 € | ||
| 50mg | 399.00 € | ||
| 100mg | 567.00 € | ||
| 200mg | 805.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
A 83-01
CAS:909910-43-6
A 83-01 (ALK5 Inhibitor IV) is a selective inhibitor of TGF-β type I receptor ALK5 …
Formula:
C25H19N5S
Purity:
97% - 98.20%
Color and Shape:
Solid
Molecular weight:
421.52
Ref: TM-T3031
| 5mg | 57.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 379.00 € | ||
| 500mg | 893.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SB-505124
CAS:694433-59-5
SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5.
Formula:
C20H21N3O2
Purity:
97.19% - 99.92%
Color and Shape:
Solid
Molecular weight:
335.4
Ref: TM-T2462
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 374.00 € | ||
| 100mg | 547.00 € | ||
| 500mg | 1,159.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Alectinib hydrochloride
CAS:1256589-74-8
Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : …
Formula:
C30H35ClN4O2
Purity:
99.61% - 99.96%
Color and Shape:
Solid
Molecular weight:
519.08
Ref: TM-T8387
| 5mg | 44.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 97.00 € | ||
| 100mg | 160.00 € | ||
| 500mg | 374.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
HG-14-10-04
CAS:1356962-34-9
HG-14-10-04 is a potent and specific ALK inhibitor.
Formula:
C29H34ClN7O
Purity:
100% - 99.75%
Color and Shape:
Solid
Molecular weight:
532.08
Ref: TM-T4015
| 1mg | 52.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 432.00 € | ||
| 200mg | 622.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SB-431542
CAS:301836-41-9
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.
Formula:
C22H16N4O3
Purity:
100% - 99.87%
Color and Shape:
Solid
Molecular weight:
384.39
Ref: TM-T1726
| 5mg | 55.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 281.00 € | ||
| 100mg | 520.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
LDN-212854
CAS:1432597-26-6
LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the …
Formula:
C25H22N6
Purity:
98% - 98.71%
Color and Shape:
Solid
Molecular weight:
406.48
Ref: TM-T1900
| 1mg | 49.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 175.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 528.00 € | ||
| 100mg | 743.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Blu-782
CAS:2141955-96-4
Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formula:
C31H42N6O4
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
562.7
Ref: TM-T8108
| 1mg | 81.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 465.00 € | ||
| 50mg | 663.00 € | ||
| 100mg | 919.00 € | ||
| 1mL*10mM (DMSO) | 212.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SB 525334
CAS:356559-20-1
SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).
Formula:
C21H21N5
Purity:
98.39% - ≥95%
Color and Shape:
Solid
Molecular weight:
343.42
Ref: TM-T1763
| 5mg | 38.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 269.00 € | ||
| 200mg | 319.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
LDN-193189 HCl
CAS:1062368-62-0
LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor.
Formula:
C25H22N6·HCl
Purity:
99.49% - 99.53%
Color and Shape:
Solid
Molecular weight:
442.94
Ref: TM-T6158
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 268.00 € | ||
| 100mg | 401.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Vactosertib Hydrochloride
CAS:1352610-25-3
Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an ALK5 inhibitor, a TGF-β receptor I inhibitor with antimetastatic …
Formula:
C22H19ClFN7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
435.89
Ref: TM-T15262
| 2mg | 86.00 € | ||
| 5mg | 100.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
A 83-01 sodium salt
CAS:2828431-89-4
A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 …
Formula:
C25H19N5NaS
Color and Shape:
Solid
Molecular weight:
444.51
Ref: TM-T10442
| 500mg | 4,036.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
ALK-IN-5
CAS:2351929-66-1
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 …
Formula:
C24H25FN6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
464.49
Ref: TM-T10283
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
TGFBR1-IN-1
CAS:2170830-26-7
TGFBR1-IN-1 is an inhibitor of ALK5 (IC50 of 10-100 nM).
Formula:
C23H17N5O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
427.48
Ref: TM-T13138
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
