ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
Found 112 products of "ALK"
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TL13-22
CAS:<p>TL13-22 is a potent inhibitor of ALK and does not lead to degradation of ALK proteins.TL13-22 is often used as a negative control for TL13-12 .</p>Formula:C45H55ClN10O9SPurity:99.13%Color and Shape:SolidMolecular weight:947.5ALK-IN-13
CAS:<p>ALK-IN-13 is an ALK inhibitor.</p>Formula:C29H39ClN7O2PColor and Shape:SolidMolecular weight:584.1ALKBH5-IN-5
CAS:<p>ALKBH5-IN-5 is a highly selective, potent and covalently binding ALKBH5 inhibitor that alters m6A levels on mRNA, induces apoptosis, antitumo.</p>Formula:C13H13NO3Purity:99.54%Color and Shape:SoildMolecular weight:231.25TL13-12
CAS:<p>TL13-12 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.69 nM).</p>Formula:C45H53ClN10O10SPurity:98%Color and Shape:SolidMolecular weight:961.49TL13-110
CAS:<p>Negative control for TL 13-112 . Displays no degradation of ALK in cell lines. Highly potent ALK inhibitor (IC50 = 0.34 nM).</p>Formula:C49H62ClN9O9SColor and Shape:SolidMolecular weight:988.59dALK-3
<p>dALK-3 is a degrader of anaplastic lymphoma kinase (ALK) that effectively induces the degradation of EML4-ALK with a DC50 of 0.182 μM. It exhibits significant antiproliferative activity against H3122 cells and is applicable for tumor research.</p>Formula:C39H45ClN7O5PColor and Shape:SolidMolecular weight:758.245FDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Color and Shape:LiquidLDN 193688
CAS:<p>LDN 193688 is a BMP kinase inhibitor preferential for the ALK2 site, acting by binding to the ALK site,progressive osseous fibrodysplasia.</p>Formula:C22H16N4OPurity:99.16%Color and Shape:SoildMolecular weight:352.39LAE-102
<p>LAE-102 is a monoclonal antibody that acts as an antagonist of activin receptor II-A (ACTRIIA/ACVR2). It shows potential for research in the fields of endocrine and metabolic disorders, oncology, and respiratory diseases.</p>Color and Shape:Odour LiquidALK-IN-12
CAS:<p>ALK-IN-12: potent ALK inhibitor (IC50: 0.18 nM), affects IGF1R and InsR (IC50: 20.3/90.6 nM), potential for cancer therapy.</p>Formula:C24H30ClN6O2PColor and Shape:SolidMolecular weight:500.97LDN-193189 Tetrahydrochloride
CAS:<p>LDN193189 is a BMPI receptor inhibitor, blocking ALK2 and ALK3 effectively, while weak on ALK4, ALK5, ALK7.</p>Formula:C25H26Cl4N6Purity:98.21%Color and Shape:SolidMolecular weight:552.33EW-7195
CAS:<p>EW-7195 inhibits ALK5/TGFβR1 (>300x selective over p38α) with 4.83 nM IC50, blocking TGF-β1 signaling, EMT, and breast cancer lung metastasis.</p>Formula:C23H18N8Purity:98.76%Color and Shape:SolidMolecular weight:406.44CEP-28122 mesylate salt
<p>CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.</p>Formula:C29H39ClN6O6SColor and Shape:SolidMolecular weight:635.17GW788388
CAS:<p>GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.</p>Formula:C25H23N5O2Purity:98.03% - 99.58%Color and Shape:SolidMolecular weight:425.48CEP-28122
CAS:<p>CEP-28122 is a highly potent and selective orally active ALK inhibitor.</p>Formula:C28H35ClN6O3Purity:99.87% - >99.99%Color and Shape:SolidMolecular weight:539.07ALK kinase inhibitor-1
CAS:<p>SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.</p>Formula:C28H32FN5O3SPurity:99.84%Color and Shape:SolidMolecular weight:537.65SM 16
CAS:<p>SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).</p>Formula:C25H26N4O3Purity:99.72%Color and Shape:SolidMolecular weight:430.5Vactosertib
CAS:<p>Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.</p>Formula:C22H18FN7Purity:98.85% - 99.81%Color and Shape:SolidMolecular weight:399.42DMH-1
CAS:<p>DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.</p>Formula:C24H20N4OPurity:98% - 99.92%Color and Shape:SolidMolecular weight:380.44Brigatinib
CAS:<p>Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.</p>Formula:C29H39ClN7O2PPurity:97.18% - >99.99%Color and Shape:SolidMolecular weight:584.09
