c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
Found 110 products of "c-Fms"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
CSF1R-IN-14
CAS:CSF1R-IN-14, an isoindolinone derivative, powerfully inhibits CSF1R, with potential in cancer research. See WO2019134662A1, compound 1.Formula:C23H22F3N5OColor and Shape:SolidMolecular weight:441.45CSF1R-IN-12
CAS:CSF1R-IN-12 is an effective CSF1R inhibitor. CSF1R-IN-12 has research potential in cancer diseases.Formula:C21H17F3N4OColor and Shape:SolidMolecular weight:398.38CSF1R-IN-7
CAS:CSF1R-IN-7 is a highly selective CSF-1R inhibitor with good brain penetration for treatment of diseases associated with microglia-mediated neuroinflammation.Formula:C22H22N6O3Purity:99.41% - 99.93%Color and Shape:SolidMolecular weight:418.45CSF1R-IN-9
CAS:CSF1R-IN-9 (Compound 46) is a CSF-1R inhibitor (IC50: 0.028 μM).Formula:C26H26N4O2Color and Shape:SolidMolecular weight:426.51CSF1R-IN-6
CAS:CSF1R-IN-6, a compound, effectively inhibits macrophage CSF1R essential for survival and differentiation.Formula:C20H18N8O3Color and Shape:SolidMolecular weight:418.41c-Fms-IN-2
CAS:c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).Formula:C19H21N3O3Purity:99.56%Color and Shape:SolidMolecular weight:339.39Ref: TM-T10775
1mg92.00€1mL*10mM (DMSO)180.00€5mg241.00€10mg355.00€25mg532.00€50mg750.00€100mg1,009.00€ABD-295
CAS:ABD-295, a biphenylsulfide derivative, inhibits osteoclasts and prevents bone loss in vitro and in vivo.Formula:C17H19F2NO3SPurity:98%Color and Shape:SolidMolecular weight:355.4c-Fms-IN-6
CAS:c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).Formula:C22H25N7O2Purity:98%Color and Shape:SolidMolecular weight:419.48IACS-9439
CAS:IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM.Formula:C23H26ClN7O3SPurity:98%Color and Shape:SolidMolecular weight:516.02c-Fms-IN-1
CAS:c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).Formula:C22H27N5O2Purity:99.94%Color and Shape:SolidMolecular weight:393.48Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formula:C27H21N3O3Purity:99.22%Color and Shape:SolidMolecular weight:435.47Ref: TM-T35570
1mg66.00€5mg144.00€1mL*10mM (DMSO)157.00€10mg245.00€25mg492.00€50mg710.00€100mg973.00€c-Fms-IN-3
CAS:c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.Formula:C23H30N6OPurity:99.87%Color and Shape:SolidMolecular weight:406.52Ref: TM-T10649
1mg52.00€5mg105.00€1mL*10mM (DMSO)110.00€10mg161.00€25mg264.00€50mg358.00€100mg522.00€c-Fms-IN-13
CAS:c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.Formula:C22H26N4O2Purity:99.93% - 99.97%Color and Shape:SolidMolecular weight:378.47Pimicotinib
CAS:Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.Formula:C22H24N6O3Purity:99.8%Color and Shape:SolidMolecular weight:420.46Ref: TM-T79157
1mg52.00€5mg111.00€1mL*10mM (DMSO)156.00€10mg170.00€25mg329.00€50mg528.00€100mg843.00€CSF1R-IN-3
CAS:CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.Formula:C30H38N8O4Purity:98.4%Color and Shape:SolidMolecular weight:574.67Ref: TM-T64066
1mg101.00€5mg245.00€1mL*10mM (DMSO)309.00€10mg358.00€25mg665.00€50mg973.00€100mg1,395.00€Ataquimast
CAS:Ataquimast is used in curing advanced receptor-positive breast cancer.Formula:C11H14ClN3OPurity:99.92%Color and Shape:SolidMolecular weight:239.7Ref: TM-T30190
1mg64.00€1mL*10mM (DMSO)116.00€5mg129.00€10mg188.00€25mg299.00€50mg427.00€100mg575.00€200mg750.00€JTE-952
CAS:JTE-952: oral, selective Type II CSF-1R inhibitor, IC50 = 13 nM for CSF1R, 261 nM for TrkA, effective in mouse arthritis model.Formula:C30H34N2O6Purity:98%Color and Shape:SolidMolecular weight:518.6c-Fms-IN-14
CAS:c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].Formula:C26H24N6OPurity:98%Color and Shape:SolidMolecular weight:436.51Axl/Mer/CSF1R-IN-2
CAS:Axl/Mer/CSF1R-IN-2 (Comp 4) serves as an inhibitor for Axl, Mer, and CSF1R [1].Formula:C24H22F3N5O5Color and Shape:SolidMolecular weight:517.46CSF1R-IN-5
CAS:CSF1R-IN-5: Potent CSF1R inhibitor, may alter TAM/glioma inflammatory exchanges, potential cancer research tool. (WO2021197276A1, Compound 11)Formula:C22H19N7O3Color and Shape:SolidMolecular weight:429.43
