c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
Found 110 products of "c-Fms"
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Axl/Mer/CSF1R-IN-1
CAS:Axl/Mer-IN-1 is a compound that functions as an inhibitor for Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R, exhibiting dissociation constants (Kds)Formula:C25H24F3N5O5Color and Shape:SolidMolecular weight:531.48Adrixetinib
CAS:Adrixetinib is an inhibitor of protein tyrosine kinase with antineoplastic activity .Formula:C25H24F3N5O5Color and Shape:SolidMolecular weight:531.48ARRY-382
CAS:ARRY-382 is a highly selective oral inhibitor of CSF-1R with an IC50 of 9 nM.
Formula:C32H36N8O2Purity:99.76%Color and Shape:SolidMolecular weight:564.68Enrupatinib
CAS:Enrupatinib is an inhibitor of the colony stimulating factor 1 receptor (CSF1R), exhibiting antitumor activity.Formula:C27H26N6O3Color and Shape:SolidMolecular weight:482.53c-Fms-IN-15
CAS:c-Fms-IN-15 (compound 8g) is a potent inhibitor of FMS kinase, with an IC50 of 563 nM.Formula:C29H28F3N7O2Molecular weight:563.57Leustroducsin B
CAS:Leustroducsin B is a novel colony-stimulating factor (CSF) inducer extracted from Streptomyces platensis SANK 60191.Formula:C34H56NO10PColor and Shape:SolidMolecular weight:669.78GENZ-882706
CAS:GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.Formula:C26H25N5O3Purity:98%Color and Shape:SolidMolecular weight:455.51Pimicotinib hydrochloride
CAS:Pimicotinib hydrochloride is an inhibitor of CSF1R, displaying antitumor activity.Formula:C22H25ClN6O3Color and Shape:SolidMolecular weight:456.925SJ-C1044
CAS:SJ-C1044 is an orally effective pan-RAF inhibitor demonstrating immunomodulatory and antitumor activities. It targets wild-type BRAF, wild-type CRAF, and BRAF(V600E) with IC50 values of 331, 257, and 187 nM, respectively. SJ-C1044 suppresses tumor cell proliferation by inhibiting kras activation and MEK-ERK phosphorylation. Additionally, it shows inhibition of VEGFR2, TIE2, and CSF1R, with IC50 values of 100, 23, and 235 nM respectively. The compound enhances the tumor immune microenvironment through inhibition of angiogenesis and modulation of macrophage function. SJ-C1044 is applicable for research in colorectal cancer.Formula:C25H14F7N7OColor and Shape:SolidMolecular weight:561.41JNJ-6204
CAS:JNJ-6204 is a deuterated compound that efficiently inhibits CSNK1D and CSNK1E.Formula:C19H11D6FN6OPurity:97.42% - 99.87%Color and Shape:SolidMolecular weight:370.41
