CymitQuimica logo
Trk receptor

Trk receptor

Trk receptor inhibitors target the Tropomyosin receptor kinases (Trk), a family of receptor tyrosine kinases that play a significant role in the development and function of the nervous system. Trk receptors are involved in neurotrophin signaling, which is essential for the survival, differentiation, and growth of neurons. Dysregulation of Trk signaling is associated with neurological disorders and certain cancers. At CymitQuimica, we offer Trk receptor inhibitors to support your research in neurobiology, oncology, and neurodegenerative diseases.

Found 58 products of "Trk receptor"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • TrkA-IN-7
    Targetmol
    + Info

    TrkA-IN-7

    CAS:
    <p>TrkA-IN-7 (Compound 4) is an inhibitor of tropomyosin receptor kinase A (TrkA), with a Kd value of 40 μM.</p>
    Formula:C16H13N3O3
    Color and Shape:Solid
    Molecular weight:295.293

    Ref: TM-T204489

  • TrkA-IN-8
    Targetmol
    + Info

    TrkA-IN-8

    CAS:
    TrkA-IN-8 (Compound 2) is a TrkA inhibitor with a Kd value of 3.3 µM. RTKs-IN-1 demonstrates a concentration-dependent inhibitory effect on the proliferation of lung cancer cell lines and holds potential for research in non-small cell lung cancer.
    Formula:C20H16N4
    Color and Shape:Solid
    Molecular weight:312.368

    Ref: TM-T205511

  • PF-06273340
    Targetmol
    + Info

    PF-06273340

    CAS:
    PF-06273340 是一种口服具有活力的、具有选择性的外周限制性Trk 泛抑制剂。
    Formula:C23H22ClN7O3
    Purity:98% - 98.00%
    Color and Shape:Solid
    Molecular weight:479.92

    Ref: TM-T19649

  • TrkC-IN-1
    Targetmol
    + Info

    TrkC-IN-1

    CAS:
    TrkC-IN-1 (Compound 6c) is an inhibitor of TrkC, with IC50 values of 3.3-7.1 and 7.3-10.2 μΜ for EBC-1 and HT-29 cells, respectively. This compound shows potential for research in the field of cancer therapeutics.
    Formula:C28H20BrN5O2
    Color and Shape:Solid
    Molecular weight:538.395

    Ref: TM-T206472

  • ONO-7579
    Targetmol
    + Info

    ONO-7579

    CAS:
    <p>ONO-7579, an orally active TRKA inhibitor, effectively suppresses tumor growth by inhibiting TRKA phosphorylation. In KM12 colorectal cancer cells, it exhibits an EC 50 of 17.6 ng/g, indicating that a concentration of 17.6 ng per gram of tumor tissue reduces the activity of phosphorylated TRKA by 50%. This compound is utilized in cancer research.</p>
    Formula:C24H18ClF3N6O4S
    Color and Shape:Solid
    Molecular weight:578.95

    Ref: TM-T200301

  • HS-345
    Targetmol
    + Info

    HS-345

    CAS:
    <p>HS-345, a TrkA/Akt inhibitor, exhibits potent anti-pancreatic cancer properties. This compound inhibits the growth and proliferation of pancreatic cancer cells by blocking the TrkA/Akt signaling pathway and induces cell apoptosis (Apoptosis). Additionally, HS-345 inhibits angiogenesis by reducing the expression of HIF-1α and VEGF. It holds promise for use in pancreatic cancer research.</p>
    Formula:C19H18N6O2S
    Color and Shape:Solid
    Molecular weight:394.45

    Ref: TM-T200230

  • Trk-IN-4
    Targetmol
    + Info

    Trk-IN-4

    CAS:
    Trk-IN-4 (PF-6683324) is a potent pan-Trk inhibitor and antinociceptive. It is also a selective type II PTK6 inhibitor antitumor.
    Formula:C24H23F4N5O4
    Purity:98.13%
    Color and Shape:Solid
    Molecular weight:521.46

    Ref: TM-T17169

    1mg
    Discontinued
    2mg
    Discontinued
    Discontinued product
  • TrkB-IN-1
    Targetmol
    + Info

    TrkB-IN-1

    CAS:
    <p>TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) properties.</p>
    Formula:C19H16N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.34

    Ref: TM-T79011

    ne
    Discontinued
    5mg
    Discontinued
    50mg
    Discontinued
    Discontinued product