VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 268 products of "VEGFR"
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T-1-MCPAB
<p>T-1-MCPAB, a VEGFR-2 inhibitor with an IC50 of 0.135 µM, effectively suppresses MCF7 cell migration and has applications in cancer research [1].</p>Purity:98%Color and Shape:Odour SolidVEGFR-2-IN-59
<p>VEGFR-2-IN-59 (Compound 3h) is an inhibitor of VEGFR2 with an IC50 of 3.73 µM. It exhibits cytotoxicity in cancer cell lines A549, HT-29, A375, MCF7, and NHDF, with IC50 values of 20.91, 19.70, 9.63, 17.43, and 20.71 μM, respectively. VEGFR-2-IN-59 also inhibits tubular structure formation and demonstrates anti-angiogenic properties.</p>Formula:C19H20N6O4Color and Shape:SolidMolecular weight:396.4VEGFR-2-IN-31
<p>VEGFR-2-IN-31 (compound 3i), a robust VEGFR-2 inhibitor (IC50=8.93 nM), serves as an anti-prostate cancer agent by arresting the cell cycle at the S-phase and</p>Formula:C15H10F2N4OPurity:98%Color and Shape:SolidMolecular weight:300.26ODM-203 sodium
<p>ODM-203 sodium is an orally bioavailable selective and efficient FGFR and VEGFR inhibitor with antitumor activity, used in solid tumor research.</p>Formula:C26H20F2N5NaO2SPurity:99.89%Color and Shape:SolidMolecular weight:527.52Tinengotinib
CAS:<p>Tinengotinib is a multikinase inhibitor that targets a series of kinases , including Aurora kinases A/B, JAK1/2, FGFR1/2/3, VEGFRs, and many other kinases.</p>Formula:C20H19ClN6OPurity:99.05%Color and Shape:SolidMolecular weight:394.86GW297361
CAS:<p>GW297361 is a potent inhibitor of the cell cycle protein-dependent kinase Cdk1 and also inhibits the Pho85 signaling pathway.The IC50s of GW297361 on yeast Cdk1</p>Formula:C16H12N4O3S2Purity:97.02%Color and Shape:SolidMolecular weight:372.42VEGFR-2-IN-35
<p>VEGFR-2-IN-35 (compound 7) is a potent inhibitor of VEGFR-2, exhibiting an IC50 of 37 nM.</p>Formula:C25H19N3O3Purity:98%Color and Shape:SolidMolecular weight:409.445Z-7-Oxozeaenol
CAS:<p>5Z-7-Oxozeaenol: TGF-β-activated kinase 1 inhibitor, IC50 8.1 nM; VEGF-R2 inhibitor, IC50 52 nM; weak MEK1 inhibitor, IC50 411 nM.</p>Formula:C19H22O7Purity:99%Color and Shape:SolidMolecular weight:362.37Tovecimig
<p>Tovecimig is a G1-scFvlh_L-κ type bispecific antibody targeting VEGFA/DLL4.</p>Color and Shape:Odour LiquidFDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Color and Shape:LiquidAngiogenesis related Compound Library
<p>A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high</p>Color and Shape:Odour SolidKinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Color and Shape:Odour SolidTyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Color and Shape:Odour SolidVulinacimab
CAS:<p>Vulinacimab (HLX-06) is a mAb targeting VEGFR-2, used in cancer research, vital for tumor angiogenesis and endothelial cell functions.</p>Color and Shape:LiquidVEGFR-2-IN-29
CAS:<p>VEGFR-2-IN-29 is a VEGFR2 inhibitor.</p>Formula:C16H11N3O3Purity:99.59%Color and Shape:SolidMolecular weight:293.28VEGFR-2-IN-33
<p>VEGFR-2-IN-33 (Compound 4d), a potent VEGFR inhibitor with an IC50 value of 61.04 nM, demonstrates significant inhibition of HepG2 cell proliferation, achieving</p>Formula:C20H14N6O2S2Purity:98%Color and Shape:SolidMolecular weight:434.49IMPDH2-IN-4
<p>IMPDH2-IN-4 (compound 2d) is a Mycophenolic acid analog and a selective IMPDH2 inhibitor with a Ki of 1.8 μM. It exhibits potent cytotoxic activity against osteosarcoma cancer cell lines. Additionally, IMPDH2-IN-4 demonstrates high affinity for VEGFR-2, CDK2, and IMPDH.</p>Formula:C35H34O6SiColor and Shape:SolidMolecular weight:578.73VEGFR-2-IN-55
<p>VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.</p>Color and Shape:Odour SolidAntiproliferative agent-57
<p>Antiproliferative agent-57 (compound M2) is a tumor angiogenesis inhibitor that suppresses VEGF secretion in SiHa cells under hypoxic conditions without inducing cytotoxicity (IC50=0.68 μM). It modulates the PI3K/AKT/mTOR and MAPK signaling pathways in tumor cells, thereby inhibiting the expression of HIF-1α and VEGF within tumor tissues.</p>Color and Shape:Odour SolidRanibizumab
CAS:<p>Ranibizumab is a humanized monoclonal antibody fragment designed to target and inhibit vascular endothelial growth factor (VEGF), including VEGF110, VEGF121,</p>Purity:98%Color and Shape:LiquidMolecular weight:149.19KD
