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FLT

FLT

FLT (Fms-like tyrosine kinase) inhibitors are compounds that target FLT receptors, which are involved in the regulation of angiogenesis through the VEGF (vascular endothelial growth factor) pathway. FLT receptors play a crucial role in the development of new blood vessels in tumors. Inhibiting FLT receptors can effectively reduce angiogenesis and tumor growth, making these inhibitors important in cancer therapy. At CymitQuimica, we offer a selection of high-quality FLT inhibitors to support your research in oncology, vascular biology, and angiogenesis.

Found 87 products for "FLT".

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  • D-65476
    Targetmol
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    D-65476

    CAS:
    D-65476 is a type III receptor tyrosine kinase (Flt3) inhibitor. It inhibits the proliferation of TEL-Flt3 transfected BA/F3 cells in the absence of IL-3, with an IC50 of 0.2 μM, and is useful for researching Flt3-driven leukemia.
    Formula:C21H18N2O3
    Color and Shape:Solid
    Molecular weight:346.38

    Ref: TM-T210001

    10mg
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    50mg
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  • Lomonitinib
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    Lomonitinib

    CAS:
    Lomonitinib is a potent and selective pan-FLT3/IRAK4 inhibitor with antitumor properties. It shows promise for research in myeloid leukemia.
    Formula:C27H24N4O2
    Color and Shape:Solid
    Molecular weight:436.505

    Ref: TM-T205470

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  • CymitQuimica logo
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    FLT3/ITD-IN-1

    FLT3/ITD-IN-1 inhibits FLT3-ITD with IC50s: 38.2 nM (FLT3) and 144.1 nM (ITD), and fights acute myeloid leukemia.
    Formula:C19H22N6O2
    Color and Shape:Solid
    Molecular weight:366.42

    Ref: TM-T61415

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CymitQuimica logo
    Targetmol
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    LT-850-166

    LT-850-166 is a potent inhibitor of FLT3 and has shown efficacy in overcoming a wide range of FLT3 mutations.
    Formula:C30H29Cl2N7O
    Color and Shape:Solid
    Molecular weight:574.5

    Ref: TM-T64062

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • JNJ-47117096
    Targetmol
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    JNJ-47117096

    CAS:
    JNJ-47117096 is a potent and selective MELK inhibitor with an IC50 of 23 nM, and it also exhibits strong activity against Flt3 with an IC50 of 18 nM.
    Formula:C21H22N4O2
    Color and Shape:Solid
    Molecular weight:362.425

    Ref: TM-T204607

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    50mg
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  • Multi-kinase inhibitor 4
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    Multi-kinase inhibitor 4

    CAS:
    Multi-kinase inhibitor 4 (compound 14) serves as an orally effective inhibitor targeting FLT1, KDR, FLT3, FLT4, PDGFRα, and PDGFRβ, exhibiting IC50 values of 1.97 nM, 1.04 nM, 0.33 nM, 1.44 nM, 0.18 nM, and 0.89 nM respectively. This compound plays a crucial role in cancer research.
    Formula:C25H24N6O2
    Color and Shape:Solid
    Molecular weight:440.50

    Ref: TM-T201144

    25mg
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    100mg
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  • E6201
    Targetmol
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    E6201

    CAS:
    E6201, a dual kinase inhibitor, blocks MEK1/FLT3 and has anti-tumor/psoriasis effects with low IC50s: ERK2 (5.2 nM), JNK (91 nM), p38 MAPK (19 nM).
    Formula:C21H27NO6
    Color and Shape:Solid
    Molecular weight:389.44

    Ref: TM-T61755

    25mg
    11,970.00€
    50mg
    16,740.00€
    100mg
    23,490.00€