FLT
FLT (Fms-like tyrosine kinase) inhibitors are compounds that target FLT receptors, which are involved in the regulation of angiogenesis through the VEGF (vascular endothelial growth factor) pathway. FLT receptors play a crucial role in the development of new blood vessels in tumors. Inhibiting FLT receptors can effectively reduce angiogenesis and tumor growth, making these inhibitors important in cancer therapy. At CymitQuimica, we offer a selection of high-quality FLT inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 92 products of "FLT"
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FLT3-IN-3
CAS:<p>FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively.</p>Formula:C27H38N8OPurity:99.25%Color and Shape:SolidMolecular weight:490.64MRX-2843
CAS:<p>MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).</p>Formula:C29H40N6OPurity:98.59% - 99.63%Color and Shape:SolidMolecular weight:488.67FLT3-IN-10
CAS:<p>FLT3-IN-10, a potent FLT3 inhibitor, may treat FLT3-mutated AML.</p>Formula:C15H11FN2OPurity:99.8%Color and Shape:SolidMolecular weight:254.26FLT3/HDAC-IN-2
<p>Compound 25h, also known as FLT3/HDAC-IN-2, is a dual inhibitor of FLT3/HDAC. It exhibits antiproliferative activity against MOLM-13 cells and is used in the study of acute myeloid leukemia.</p>Color and Shape:Odour Solid2-Butenamide
CAS:<p>2-Butenamide, FLT3 inhibitor. Affordable Excellence: Reliable Quality You Can Trust</p>Formula:C4H7NOColor and Shape:SolidMolecular weight:85.1JAK3-IN-14
CAS:<p>JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.</p>Formula:C18H13N3OPurity:98.29%Color and Shape:SoildMolecular weight:287.32Pacritinib citrate
CAS:<p>Pacritinib (SB1518) citrate effectively inhibits wild-type JAK2 (IC 50 =23 nM) and the JAK2 V617F mutant (IC 50 =19 nM). It also targets FLT3 (IC 50 =22 nM) and the FLT3 D835Y mutant (IC 50 =6 nM). This compound is utilized in the study of acute myeloid leukemia (AML) and myelofibrosis (MF) [1] [2] [3].</p>Formula:C34H40N4O10Color and Shape:SolidMolecular weight:664.7PF15 TFA
<p>PF15 TFA, a PROTAC targeting FLT3 kinase and CRBN, exhibits selective degradation of FLT3-ITD with a DC50 of 76.7 nM.</p>Formula:C46H50F3N13O8Purity:98%Color and Shape:SolidMolecular weight:969.97PF15
CAS:<p>PF15, a PROTAC for FLT3-ITD, degrades FLT3 kinase. DC50: 76.7 nM; hinders FLT3-ITD+ cell growth; potential in leukemia.</p>Formula:C44H49N13O6Purity:98%Color and Shape:SolidMolecular weight:855.94FLT3 Ligand-Linker Conjugate 1
CAS:<p>FLT3 Ligand-Linker Conjugate 1 consists of an FLT3 ligand and a PROTAC linker that can recruit E3 ligase VHL. This conjugate is useful for synthesizing PROTAC RSS0680, a bifunctional compound designed for targeted protein degradation of kinases.</p>Formula:C29H34N6O4S2Color and Shape:SolidMolecular weight:594.748FLT3-IN-23
<p>FLT3-IN-23 (compound 15), a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3), exhibits an IC 50 value of 7.42 nM and demonstrates antiproliferative effects</p>Color and Shape:Odour SolidHSK205
<p>HSK205 is a dual FLT3 and haspin inhibitor, exhibiting potent antitumor activity [1], with an IC50 of 0.187 nM for FLT3.</p>Color and Shape:Odour SolidFLT3-IN-20
<p>FLT3-IN-20 (compound 34f) is a potent FLT3 inhibitor, demonstrating IC50 values of 1 nM for FLT3-D835Y and 4 nM for FLT3-ITD.</p>Formula:C28H33N7O2SColor and Shape:SolidMolecular weight:531.67FLT3-IN-22
<p>FLT3-IN-22 (compound 22f) is a potent inhibitor of FLT3, demonstrating IC50 values of 0.941 nM for FLT3 and 0.199 nM for the FLT3/D835Y mutant.</p>Formula:C24H22N6O2Color and Shape:SolidMolecular weight:426.47FLT3-ITD-IN-2
<p>FLT3-ITD-IN-2 (Compound A1) is an inhibitor of the FLT3-ITD kinase, exhibiting an IC50 of 2.12 nM. It effectively suppresses the proliferation of the FLT3-dependent human AML cell line MOLM-13, with an IC50 of 25.65 nM. FLT3-ITD-IN-2 demonstrates antitumor activity against acute myeloid leukemia.</p>Formula:C39H50N8O6Color and Shape:SolidMolecular weight:726.86FLT3/VEGFR2-IN-1
<p>FLT3/VEGFR2-IN-1 (Compound 26) is a potent inhibitor of FLT3, VEGFR2, and HDAC, exhibiting IC50 values of 14.5 nM, 3.9 nM, and 30.8 nM against FLT3, VEGFR2, and HDAC1, respectively. It effectively inhibits the phosphorylation of STAT3 and ERK1/2, as well as the proliferation of leukemia cells. FLT3/VEGFR2-IN-1 demonstrates antitumor activity and is applicable in research on acute myeloid leukemia.</p>Formula:C29H35N7O5Color and Shape:SolidMolecular weight:561.633-Hydroxy Midostaurin
CAS:<p>3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 values of roughly 132 nM in</p>Formula:C35H30N4O5Purity:98%Color and Shape:SolidMolecular weight:586.648Anti-FLT1 Antibody (6K171)
<p>Anti-FLT1 Antibody (6K171) is a Mouse antibody targeting FLT1. Anti-FLT1 Antibody (6K171) can be used in ELISA,ICC/IF.</p>Color and Shape:Odour LiquidAnti-VEGFR1/FLT-1 Antibody (9F18)
<p>Anti-VEGFR1/FLT-1 Antibody (9F18) is a Rabbit antibody targeting VEGFR1/FLT-1. Anti-VEGFR1/FLT-1 Antibody (9F18) can be used in ELISA.</p>Color and Shape:Odour LiquidAnti-FLT1 Antibody (6S618)
<p>Anti-FLT1 Antibody (6S618) is an antibody targeting FLT1. Anti-FLT1 Antibody (6S618) can be used in ELISA, IHC.</p>Color and Shape:Odour LiquidAnti-FLT1 Antibody (3W705)
<p>Anti-FLT1 Antibody (3W705) is an antibody targeting FLT1. Anti-FLT1 Antibody (3W705) can be used in ELISA, WB, IHC, FCM.</p>Color and Shape:Odour LiquidFLT3-IN-16
CAS:<p>FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.</p>Formula:C15H15N3O2SPurity:99.21%Color and Shape:SolidMolecular weight:301.36SB1317
CAS:<p>SB1317 (TG02) is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).</p>Formula:C23H24N4OPurity:99.86%Color and Shape:SolidMolecular weight:372.46BPR1K871
CAS:<p>BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values of</p>Formula:C25H28ClN7O2SColor and Shape:SolidMolecular weight:526.05FLT1 Protein, Human, Recombinant (aa 1-328, His)
<p>FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag.</p>Purity:97.5%Color and Shape:Lyophilized PowderMolecular weight:35.6 kDa (predicted)VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
<p>VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Color and Shape:Lyophilized PowderMolecular weight:85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.FLT1 Protein, Human, Recombinant (hFc)
<p>FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:61.1 kDa (predicted)VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
<p>VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Color and Shape:Lyophilized PowderMolecular weight:85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.FLT1 Protein, Human, Recombinant (aa 1-756, His)
<p>FLT1 Protein, Human, Recombinant (aa 1-756, His) is expressed in HEK293 mammalian cells with His tag.</p>Color and Shape:Lyophilized PowderMolecular weight:83.7 kDa (predicted); 110-120 kDa (reducing condition, due to glycosylation)FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
<p>FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.</p>Color and Shape:Lyophilized PowderMolecular weight:85.45 kDa (predicted); 113.32 kDa (reducing conditions)Fostamatinib Disodium
CAS:<p>Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.</p>Formula:C23H24FN6O9P·2NaPurity:96.13% - 99.09%Color and Shape:SolidMolecular weight:624.42Gilteritinib
CAS:<p>Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,</p>Formula:C29H44N8O3Purity:97.75% - 99.90%Color and Shape:SolidMolecular weight:552.71CCT241736
CAS:<p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>Formula:C22H23Cl2N7Purity:96.2% - 99.81%Color and Shape:SolidMolecular weight:456.37NVP-AEW541
CAS:<p>NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based</p>Formula:C27H29N5OPurity:98.7% - 99.86%Color and Shape:SolidMolecular weight:439.554SC-203
CAS:<p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>Formula:C33H38N8O4SPurity:96.4% - 99.67%Color and Shape:SolidMolecular weight:642.77BPR1J-097
CAS:<p>BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM).</p>Formula:C27H28N6O3SPurity:99.3%Color and Shape:SolidMolecular weight:516.61UNC2025
CAS:<p>UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor.</p>Formula:C28H40N6OPurity:99.53% - 99.74%Color and Shape:SolidMolecular weight:476.66TCS 359
CAS:<p>TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.</p>Formula:C18H20N2O4SPurity:99.31%Color and Shape:SolidMolecular weight:360.43BPR1J-097 hydrochloride (1327167-19-0(free base))
<p>BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.</p>Formula:C27H29ClN6O3SPurity:98% - 98.54%Color and Shape:SolidMolecular weight:553.07FLT3-IN-2
CAS:<p>FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).</p>Formula:C21H16ClF3N4Purity:97.57% - 98.53%Color and Shape:SolidMolecular weight:416.83HPK1-IN-2
CAS:<p>HPK1-IN-2 is a strong, oral HPK1 inhibitor (IC50<0.05 μM), also blocking Lck, Flt3 kinases, with anticancer properties.</p>Formula:C19H20N6OSPurity:97.31%Color and Shape:SolidMolecular weight:380.47(E/Z)-Zotiraciclib
CAS:<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.</p>Formula:C23H24N4OPurity:97.75% - 99.92%Color and Shape:SolidMolecular weight:372.46Crenolanib
CAS:<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Formula:C26H29N5O2Purity:98.40% - 99.73%Color and Shape:SolidMolecular weight:443.545'-Fluoroindirubinoxime
CAS:<p>5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).</p>Formula:C16H10FN3O2Purity:>99.99%Color and Shape:SolidMolecular weight:295.27UNC2025 2HCl (1429881-91-3(free base))
<p>UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.</p>Formula:C28H42Cl2N6OPurity:99.71%Color and Shape:SolidMolecular weight:549.62SGI-7079
CAS:<p>SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.</p>Formula:C26H26FN7Purity:95.51% - 99.26%Color and Shape:SolidMolecular weight:455.53SB1317 hydrochloride (1204918-72-8(free base))
<p>SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).</p>Formula:C23H25ClN4OPurity:99.84%Color and Shape:SolidMolecular weight:408.92AMG 925
CAS:<p>AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.</p>Formula:C26H29N7O2Purity:99.75%Color and Shape:SolidMolecular weight:471.55UNC2541
CAS:<p>UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.</p>Formula:C24H34FN7O2Purity:98.33%Color and Shape:SolidMolecular weight:471.57Pacritinib
CAS:<p>Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).</p>Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58
