Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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Gefitinib-d6
CAS:Gefitinib-d6 is a deuterated compound of Gefitinib. Gefitinib has a CAS number of 184475-35-2. Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM).Formula:C22H18D6ClFN4O3Color and Shape:SolidMolecular weight:452.94Reserpine-d9
CAS:Reserpine-d9 is a deuterated compound of Reserpine. Reserpine has a CAS number of 50-55-5. Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.Formula:C33H31D9N2O9Color and Shape:SolidMolecular weight:617.73Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purity:99.46% - 99.66%Color and Shape:SolidMolecular weight:441.46Alisol A
CAS:Alisol A: induces autophagy, anti-cancer, inhibits HepG2, MDA-MB-231, MCF-7 cells.
Formula:C30H50O5Purity:99.77% - 99.94%Color and Shape:SolidMolecular weight:490.71MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurity:99.22%Color and Shape:SolidMolecular weight:461.94Atorvastatin
CAS:Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.Formula:C33H35FN2O5Purity:99.37% - 99.69%Color and Shape:SolidMolecular weight:558.64BGT226 maleate
CAS:BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .Formula:C28H25F3N6O2·C4H4O4Purity:97.75% - 98.77%Color and Shape:SolidMolecular weight:650.6Ref: TM-T6072
1mg35.00€5mg73.00€10mg108.00€25mg230.00€50mg339.00€100mg485.00€200mg665.00€1mL*10mM (DMSO)94.00€Bexarotene
CAS:Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).Formula:C24H28O2Purity:99% - 99.65%Color and Shape:White SolidMolecular weight:348.48VX-702
CAS:VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formula:C19H12F4N4O2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:404.32Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44Ref: TM-T2S2362
1mg89.00€5mg205.00€10mg334.00€25mg552.00€50mg782.00€100mg1,054.00€200mg1,414.00€1mL*10mM (DMSO)243.00€Rac-Efavirenz
CAS:Rac-Efavirenz is a non stereospecific structure of Efavirenz.Formula:C14H9ClF3NO2Color and Shape:SolidMolecular weight:315.67Metyrapone Tartrate
CAS:Metyrapone Tartrate: a test inhibitor for diagnosing Cushing's; blocks steroid 11-beta-hydroxylase.Formula:C22H26N2O13Color and Shape:SolidMolecular weight:526.45Euchrysine 3RX
CAS:Euchrysine 3RX is an agent of bioactive chemicals.Formula:C20H26BrCl2N3OPurity:98%Color and Shape:Brown PowderMolecular weight:475.25Chloroquine dihydrochloride
CAS:Chloroquine: treats malaria, amebiasis, rheumatoid arthritis, lupus; works by inhibiting parasites in red blood cells.Formula:C18H27Cl2N3Color and Shape:SolidMolecular weight:356.33Lamotrigine-d3
CAS:Lamotrigine-d3 is a deuterated compound of Lamotrigine. Lamotrigine has a CAS number of 84057-84-1. Lamotrigine is an Anti-epileptic Agent and Mood Stabilizer. The physiologic effect of lamotrigine is by means of Decreased Central Nervous System Disorganized Electrical Activity.Formula:C9D3H4Cl2N5Color and Shape:SolidMolecular weight:259.11Apatinib-d8
CAS:Apatinib-d8 is a deuterated compound of Apatinib. Apatinib has a CAS number of 811803-05-1. Apatinib is an orally bioavailable and specific VEGFR2 inhibitor (IC50: 1 nM). In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.Formula:C24H15D8N5OColor and Shape:SolidMolecular weight:405.52Erlotinib mesylate
CAS:Erlotinib: reversible inhibitor binding to ATP site of epidermal growth factor receptor.Formula:C23H27N3O7SPurity:98%Color and Shape:SolidMolecular weight:489.54TAMRA alkyne, 6-isomer
CAS:TAMRA alkyne, 6-isomer: a xanthene dye linker with orange emission, used for DNA/RNA labeling, reacts via Click Chemistry.
Formula:C28H25N3O4Color and Shape:SolidMolecular weight:467.52Seriniquinone
CAS:Seriniquinone is a selective agent of anticancer that acts by inducing cell death via autophagocytosis and targeting the cancer-protective protein dermcidin.Formula:C20H8O4SPurity:98%Color and Shape:SolidMolecular weight:344.34PBA-1105
CAS:PBA-1105, an autophagy-targeting chimeric molecule (AUTOTAC), facilitates the self-oligomerization of p62. Additionally, PBA-1105 enhances the autophagic flux of Ub-conjugated aggregates.Formula:C39H48N2O6Color and Shape:SolidMolecular weight:640.81Gavilimomab
CAS:Gavilimomab(ABX-CBL) is a murine-derived IgM monoclonal antibody against CD147 antigen used in immunosuppressive treatments for glucocorticoid-resistant GVHD).Purity:95%Color and Shape:LiquidMolecular weight:0YT-8-8
CAS:YT-8-8 is a ligand for the p62-ZZ domain and can activate p62-dependent selective autophagy. This compound is also applicable in AUTOTAC design.Formula:C18H23FN2O2Color and Shape:SolidMolecular weight:318.39Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Formula:C16H25NO4·HClPurity:98.72% - 99.48%Color and Shape:White SolidMolecular weight:331.15Resveratrol analog 2
CAS:Resveratrol analog 2 mimics Resveratrol, a natural antioxidant with anti-inflammatory, cardioprotective, and anticancer benefits.Formula:C16H13FO3Purity:98%Color and Shape:SolidMolecular weight:272.27Paroxetine hydrochloride hemihydrate
CAS:Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).Formula:C38H44Cl2F2N2O7Purity:99.949%Color and Shape:SolidMolecular weight:749.67SU11274
CAS:SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formula:C28H30ClN5O4SPurity:98.62% - 99.53%Color and Shape:Orange PowderMolecular weight:568.09Ref: TM-T6154
1mg44.00€2mg56.00€5mg92.00€10mg142.00€25mg268.00€50mg442.00€100mg652.00€1mL*10mM (DMSO)142.00€Xantocillin
CAS:Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.Formula:C18H12N2O2Purity:98%Color and Shape:SolidMolecular weight:288.3GPR35 agonist 1
CAS:GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).Formula:C10H4BrN5O5Purity:98%Color and Shape:SolidMolecular weight:354.07AMG 487 (S-enantiomer)
CAS:AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.Formula:C32H28F3N5O4Purity:98%Color and Shape:SolidMolecular weight:603.59AGN 205327
CAS:AGN 205327 is a potent synthetic RAR agonist,showing selective RAR activation without RXR inhibition for retinoid research.Formula:C24H26N2O3Purity:99.45% - 99.71%Color and Shape:SolidMolecular weight:390.47IZCZ-3
CAS:IZCZ-3,antitumor activity. is a potent c-MYC transcription inhibitor.Formula:C46H49N7OPurity:98%Color and Shape:SolidMolecular weight:715.93LS2265
CAS:LS2265, a fenofibrate derivative with a taurine modification, effectively induces the proliferation of peroxisomes in rat liver cells.Formula:C19H20ClNO6SPurity:98%Color and Shape:SolidMolecular weight:425.88SR12418
CAS:SR12418 is a specific synthetic ligand for REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. inhibits IL-17A expression in EL4 cells.Formula:C31H30FNO3Purity:99.96%Color and Shape:SolidMolecular weight:483.57VUF10132
CAS:VUF10132 is a full inverse CXCR3 N3.35A agonist.Formula:C19H13BrCl4N2O2Purity:98%Color and Shape:SolidMolecular weight:523.03AL 8697
CAS:AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.Formula:C21H21F3N4OPurity:99.55% - 99.89%Color and Shape:SolidMolecular weight:402.41Ref: TM-T10277
1mg66.00€5mg138.00€10mg195.00€25mg329.00€50mg469.00€100mg642.00€500mgTo inquire1mL*10mM (DMSO)160.00€GPP78
CAS:GPP78: Strong Nampt inhibitor, IC50 3.0 nM, depletes NAD. Kills SH-SY5Y cells, IC50 3.8 nM via autophagy. Anti-cancer and anti-inflammatory.Formula:C27H29N5OPurity:98%Color and Shape:SolidMolecular weight:439.55(Rac)-BL-918
CAS:(Rac)-BL-918 is the racemic form of BL-918. BL-918 is an effective activator of UNC-51-like kinase 1 (ULK1) (EC₅₀ = 24.14 nM), Parkinson's disease.Formula:C23H15F8N3OSPurity:97.03%Color and Shape:SolidMolecular weight:533.44Ref: TM-T12662
1mg48.00€5mg90.00€10mg136.00€25mg269.00€50mg467.00€100mg755.00€200mg1,027.00€1mL*10mM (DMSO)99.00€RNF5 inhibitor inh-02
CAS:RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR cystic fibrosis (CF).Formula:C23H20N4SPurity:99.23%Color and Shape:SolidMolecular weight:384.5Ref: TM-T35883
1mg81.00€5mg170.00€10mg295.00€25mg620.00€50mg1,063.00€100mg1,783.00€200mg2,412.00€1mL*10mM (DMSO)178.00€YOK-2204
CAS:YOK-2204 is a ligand for the p62-ZZ domain and activates p62-dependent selective autophagy. It is also applicable in the design of AUTOTACs.Formula:C28H35NO4Color and Shape:SolidMolecular weight:449.58MRT-68601 HCl
CAS:MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.Formula:C25H34N6O2Purity:98%Color and Shape:SolidMolecular weight:450.58TUN-92046
CAS:TUN-92046 is a permeable alpha-ketoglutarate analog that blocks harmful autophagy in cardiomyopathy.Formula:C7H10O5Purity:95.48% - 98.58%Color and Shape:SolidMolecular weight:174.15OSU-53
CAS:OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.Formula:C25H24F3N3O6S2Color and Shape:SolidMolecular weight:583.6VUF5834
CAS:VUF5834 is a full inverse agonist of CXCR3 N3.35A.Formula:C31H41N5O2Purity:98%Color and Shape:SolidMolecular weight:515.69YM-155 hydrochloride
CAS:Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].Formula:C20H19ClN4O3Color and Shape:SolidMolecular weight:398.85ATG7-IN-3
CAS:ATG7-IN-3 (Compound 18) is an effective ATG7 inhibitor (IC₅₀ = 48 nM), suppressing autophagy, suitable for research into gliomas and colorectal cancers.Formula:C11H16N6O5S2Purity:99.74% - 99.88%Color and Shape:SolidMolecular weight:376.41Evogliptin
CAS:Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.Formula:C19H26F3N3O3Color and Shape:SolidMolecular weight:401.42(R)-Hydroxychloroquine
CAS:(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine is an agent of synthetic antimalarial.Formula:C18H26ClN3OPurity:98%Color and Shape:SolidMolecular weight:335.87eIF4A3-IN-2
CAS:eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.Formula:C25H19Br2ClN4O2Purity:98%Color and Shape:SolidMolecular weight:602.71IT1t
CAS:IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.Formula:C21H34N4S2Purity:98%Color and Shape:SolidMolecular weight:406.65Sulfosuccinimidyl oleate
CAS:Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.Formula:C22H37NO7SPurity:98%Color and Shape:SolidMolecular weight:459.6Ipsalazide
CAS:Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.
Formula:C16H11N3Na2O6Purity:99.43%Color and Shape:SolidMolecular weight:387.25rac-NBI-74330
CAS:rac-NBI-74330 is an effective and selective CXCR3 antagonist.Formula:C32H27F4N5O3Purity:99.6%Color and Shape:SolidMolecular weight:605.58MPM-1
MPM-1, a marine mimic, induces rapid necrotic-like death in cancer cells, disrupts autophagy, and causes lysosomal swelling.Formula:C34H44F6N4O7Color and Shape:SolidMolecular weight:734.73FAAH inhibitor 1
CAS:FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Formula:C24H23N3O3S3Purity:99.6%Color and Shape:SolidMolecular weight:497.65Ref: TM-T11256
1mg38.00€5mg86.00€10mg124.00€25mg203.00€50mg294.00€100mg411.00€200mg553.00€1mL*10mM (DMSO)94.00€PX20606 trans racemate
CAS:PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).Formula:C29H22Cl3NO4Purity:98%Color and Shape:SolidMolecular weight:554.85Autophagy inducer 4
CAS:Autophagy inducer 4, a Magnolol-based Mannich derivative, is an anticancer agent that blocks cancer cell migration & is 76x more toxic to T47D cells.Formula:C32H37NO6Color and Shape:SolidMolecular weight:531.64ALLO-1
CAS:ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.Formula:C17H15ClN2O2Purity:98%Color and Shape:SolidMolecular weight:314.77KRH-1636
CAS:KRH-1636: potent, selective CXCR4 antagonist; orally active; inhibits X4 HIV-1 by blocking viral entry and membrane fusion.Formula:C32H37N7O2Color and Shape:SolidMolecular weight:551.68(S)-Hydroxychloroquine
CAS:(S)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine shows efficiently inhibits SARS-CoV-2 infection in vitro.Formula:C18H26ClN3OPurity:98%Color and Shape:SolidMolecular weight:335.87TN-14003
CAS:TN-14003 is a synthetic antagonist 14-mer peptide inhibiting metastasis in an animal model.Formula:C90H141N33O18S2Color and Shape:SolidMolecular weight:2037.42SX-517
CAS:SX-517 is a non-competitive dual antagonist of CXCR1/2, demonstrating anti-inflammatory effects, inhibits CXCL-1-induced Ca²⁺ flux.Formula:C19H16BFN2O3SPurity:99.9% - 99.90%Color and Shape:SolidMolecular weight:382.22KSI-3716
CAS:KSI-3716 is a c-Myc inhibitor, a bladder chemotherapy agent that blocks the formation of complexes between c-MYC/MAX and target gene promoters.Formula:C17H11BrCl2N2O2Purity:98.94%Color and Shape:SolidMolecular weight:426.09MOPIPP
CAS:MOPIPP: crosses blood-brain barrier, fights glioblastoma, induces vacuolization, boosts autophagy, triggers methuosis, hinders glucose metabolism.Formula:C20H20N2O2Color and Shape:SolidMolecular weight:320.39SA72
CAS:SA72 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH).Formula:C21H26N2O6Purity:98%Color and Shape:SolidMolecular weight:402.44Elliptinium acetate
CAS:Elliptinium acetate (NSC 264137), a cytotoxic DNA intercalator for cancer research, targets L1210 cells.Formula:C20H20N2O3Color and Shape:SolidMolecular weight:336.38Aliskiren fumarate
CAS:Oral renin inhibitor Aliskiren fumarate treats hypertension; IC50: 1.5 nM. Useful for cardiovascular and cancer cachexia research.Formula:C34H57N3O10Color and Shape:SolidMolecular weight:667.83Levomepromazine Maleate
CAS:Levomepromazine Maleate: TCA and SNRI with antihistamine, antiadrenergic, and anticholinergic properties.Formula:C23H28N2O5SColor and Shape:SolidMolecular weight:444.546CXCR3 Antagonist 6c
CAS:CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM & 100 nM) with selectivity over 14 other GPCRs.Formula:C30H32Cl3N5O3Color and Shape:SolidMolecular weight:616.978-Nitro-cGMP
CAS:8-Nitro-cGMP is a unique cytoprotective mediator which inhibits oxidative stress. 8-Nitro-cGMP is also a probe of the protein S-guanylation.Formula:C10H11N6O9PColor and Shape:SolidMolecular weight:390.20ATG7-IN-2
CAS:ATG7-IN-2 inhibits ATG7 protein with 0.089 μM IC50 and suppresses autophagy marker LC3B.Formula:C11H16N6O7SColor and Shape:SolidMolecular weight:376.35CC214-2
CAS:CC214-2: strong dual mTORC1/2 inhibitor, blocks autophagy, may shorten TB duration.Formula:C20H25N5O3Color and Shape:SolidMolecular weight:383.44HF51116
CAS:HF51116 blocks XCR4, hinders SDF-1α cell effects & HIV-1; potential for HIV, stem cells, cancer spread.Formula:C29H46N8OColor and Shape:SolidMolecular weight:522.73AC-55649
CAS:AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.Formula:C21H26O2Purity:99.98%Color and Shape:SolidMolecular weight:310.43STK683963
CAS:STK683963 activates ATG4B, mediates redox regulation, and aids cancer research.Formula:C12H8FN3O2SColor and Shape:SolidMolecular weight:277.27Obatoclax
CAS:Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.Formula:C20H19N3OPurity:99.44%Color and Shape:SolidMolecular weight:317.38CXCR4 antagonist 9
CAS:CXCR4 antagonist 9, with IC50s of 15 nM & 1.3 nM against CXCR4 & Ca²⁺ rise by CXCL12 respectively.Formula:C21H27FN6Color and Shape:SolidMolecular weight:382.48Dilmapimod tosylate
CAS:Dilmapimod tosylate, a p38 MAPK inhibitor, targets IL-1β, was in phase III trials by GlaxoSmithKline for rheumatoid arthritis and more.Formula:C30H27F3N4O6SColor and Shape:SolidMolecular weight:628.62PF 750
CAS:PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.Formula:C22H23N3OPurity:99.87%Color and Shape:SolidMolecular weight:345.44Ref: TM-T16515
2mg37.00€5mg58.00€10mg93.00€25mg177.00€50mg281.00€100mg420.00€200mg602.00€500mg888.00€1mL*10mM (DMSO)64.00€CXCR4 antagonist 8
CAS:CXCR4 antagonist 8 (Compound 3) blocks CXCR4, IC50 of 57 nM; stops CXCL12-induced Ca2+ increase, IC50 of 0.24 nM; hinders cell migration.Formula:C21H26N6Color and Shape:SolidMolecular weight:362.47Antiproliferative agent-5
CAS:Compound 4o inhibits gastric cancer growth, blocks G2/M cell cycle, induces ROS, and triggers autophagy. Used in anti-cancer studies.Formula:C28H21BrN8OSColor and Shape:SolidMolecular weight:597.49AUTEN-67
CAS:AUTEN-67 inhibits MTMR14, boosts autophagy, has antiaging/neuroprotective properties, and combats Huntington's disease onset/severity.Formula:C23H14N4O6SColor and Shape:SolidMolecular weight:474.45VUF11211
CAS:VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.Formula:C26H35Cl2N5OPurity:98%Color and Shape:SolidMolecular weight:504.49Autophagy-IN-C1
CAS:Autophagy-IN-C1 is a cinchona alkaloid derivative containing urea.Formula:C29H28F6N4O2Color and Shape:SolidMolecular weight:578.55SB-332235
CAS:SB-332235 is an effective specific CXCR2 antagonist. And it is effectively inhibited CS-induced neutrophilia in a dose-dependent manner.Formula:C13H10Cl3N3O4SColor and Shape:SolidMolecular weight:410.66Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurity:99.84%Color and Shape:Clear In WaterMolecular weight:367.4Fluoxetine oxalate
CAS:Fluoxetine oxalate, an SSRI, treats depression, OCD, bulimia, panic, and PMS.Formula:C19H20F3NO5Color and Shape:SolidMolecular weight:399.36Glaucocalyxin B
CAS:Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).Formula:C22H30O5Purity:99.13% - 99.35%Color and Shape:SolidMolecular weight:374.47Nicodicosapent
CAS:Nicodicosapent is a fatty acid niacin conjugate that inhibits SREBP, a regulator of cholesterol metabolism.Formula:C28H39N3O2Purity:98%Color and Shape:SolidMolecular weight:449.63Methophenazine diethanesulfonate
CAS:Methophenazine diethanesulfonate is a Calmodulin antagonist.Formula:C35H48ClN3O11S3Color and Shape:SolidMolecular weight:818.41ICT5040
CAS:ICT5040 is a CXCR4 antagonist.Formula:C10H8F3N3OSColor and Shape:SolidMolecular weight:275.25Ambroxol-d5
CAS:Ambroxol-d5 is a standard for quantifying ambroxol in GC/LC-MS, an expectorant metabolite of bromhexine improving mucociliary functions.Formula:C13H13Br2D5N2OColor and Shape:SolidMolecular weight:383.13Norswertianin
CAS:Norswertianin, a xanthone, induces GBM cell differentiation and autophagy via oxidative stress and Akt/mTOR.Formula:C13H8O6Color and Shape:SolidMolecular weight:260.2AMD 3465
CAS:AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).Formula:C24H38N6Purity:98%Color and Shape:SolidMolecular weight:410.60Olacaftor
CAS:Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).Formula:C29H34FN3O4SColor and Shape:SolidMolecular weight:539.66CP-53631
CAS:CP-53631 is a selective serotonin reuptake inhibitor (SSRI)Formula:C17H19BrClNColor and Shape:SolidMolecular weight:352.7Quinacrine analog 34
CAS:Quinacrine: anti-protozoal, autophagy inhibitor (toxic at 2.5 μM). Analog 34 less toxic (LD50 = 27 μM), raises LC3-II protein, deacidifies lysosomes.Formula:C20H27ClN4Color and Shape:SolidMolecular weight:358.91GSK812397
CAS:GSK812397 inhibits X4-tropic HIV-1 with high potency, targeting CXCR4 receptor noncompetitively and showing broad efficacy and good pharmacokinetics.Formula:C24H32N6OColor and Shape:SolidMolecular weight:420.55SMYD3-IN-2
SMYD3-IN-2, a cancer research chemical, inhibits SMYD3 (IC50 0.81 μM) and BGC823 (IC50 0.75 μM), inducing fatal autophagy in gastric cancer.Formula:C26H21BrN2O4Color and Shape:SolidMolecular weight:505.36CXCR4 modulator-2
CAS:CXCR4 modulator-2 (Z7R) has high potency (IC50: 1.25 nM), stable in mouse serum (t1/2=77.1 min), and anti-inflammatory in mice.Formula:C21H32N8O2Color and Shape:SolidMolecular weight:428.53SMER18
CAS:SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.Formula:C16H14ClNO2Purity:97.27%Color and Shape:SolidMolecular weight:287.74Ref: TM-T16900
1mg84.00€5mg187.00€10mg269.00€25mg520.00€50mg803.00€100mg1,063.00€1mL*10mM (DMSO)205.00€
