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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • Norswertianin

    CAS:
    <p>Norswertianin, a xanthone, induces GBM cell differentiation and autophagy via oxidative stress and Akt/mTOR.</p>
    Formula:C13H8O6
    Color and Shape:Solid
    Molecular weight:260.2
  • ICT5040

    CAS:
    <p>ICT5040 is a CXCR4 antagonist.</p>
    Formula:C10H8F3N3OS
    Color and Shape:Solid
    Molecular weight:275.25
  • SB-332235

    CAS:
    <p>SB-332235 is an effective specific CXCR2 antagonist. And it is effectively inhibited CS-induced neutrophilia in a dose-dependent manner.</p>
    Formula:C13H10Cl3N3O4S
    Color and Shape:Solid
    Molecular weight:410.66
  • Autophagy-IN-C1

    CAS:
    <p>Autophagy-IN-C1 is a cinchona alkaloid derivative containing urea.</p>
    Formula:C29H28F6N4O2
    Color and Shape:Solid
    Molecular weight:578.55
  • Olacaftor

    CAS:
    <p>Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).</p>
    Formula:C29H34FN3O4S
    Color and Shape:Solid
    Molecular weight:539.66
  • PF 750

    CAS:
    <p>PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.</p>
    Formula:C22H23N3O
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:345.44
  • AMD 3465

    CAS:
    <p>AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).</p>
    Formula:C24H38N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:410.60
  • VUF11211

    CAS:
    <p>VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.</p>
    Formula:C26H35Cl2N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:504.49
  • AUTEN-67

    CAS:
    <p>AUTEN-67 inhibits MTMR14, boosts autophagy, has antiaging/neuroprotective properties, and combats Huntington's disease onset/severity.</p>
    Formula:C23H14N4O6S
    Color and Shape:Solid
    Molecular weight:474.45
  • LV-320

    CAS:
    <p>LV-320, potent ATG4B inhibitor; IC50: 24.5 μM, Kd: 16 μM. Blocks autophagy, stable, non-toxic, active in vivo. Useful for ATG4B research in cancer.</p>
    Formula:C29H26ClNO2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:520.11
  • Antiproliferative agent-5

    CAS:
    <p>Compound 4o inhibits gastric cancer growth, blocks G2/M cell cycle, induces ROS, and triggers autophagy. Used in anti-cancer studies.</p>
    Formula:C28H21BrN8OS
    Color and Shape:Solid
    Molecular weight:597.49
  • CXCR4 antagonist 9

    CAS:
    <p>CXCR4 antagonist 9, with IC50s of 15 nM &amp; 1.3 nM against CXCR4 &amp; Ca²⁺ rise by CXCL12 respectively.</p>
    Formula:C21H27FN6
    Color and Shape:Solid
    Molecular weight:382.48
  • SA 47

    CAS:
    <p>SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.</p>
    Formula:C17H26N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:334.41
  • CXCR4 antagonist 8

    CAS:
    <p>CXCR4 antagonist 8 (Compound 3) blocks CXCR4, IC50 of 57 nM; stops CXCL12-induced Ca2+ increase, IC50 of 0.24 nM; hinders cell migration.</p>
    Formula:C21H26N6
    Color and Shape:Solid
    Molecular weight:362.47
  • ALLO-1

    CAS:
    <p>ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.</p>
    Formula:C17H15ClN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:314.77
  • Obatoclax

    CAS:
    <p>Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.</p>
    Formula:C20H19N3O
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:317.38
  • Nicodicosapent

    CAS:
    <p>Nicodicosapent is a fatty acid niacin conjugate that inhibits SREBP, a regulator of cholesterol metabolism.</p>
    Formula:C28H39N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:449.63
  • STK683963

    CAS:
    <p>STK683963 activates ATG4B, mediates redox regulation, and aids cancer research.</p>
    Formula:C12H8FN3O2S
    Color and Shape:Solid
    Molecular weight:277.27
  • LS2265

    CAS:
    <p>LS2265, a fenofibrate derivative with a taurine modification, effectively induces the proliferation of peroxisomes in rat liver cells.</p>
    Formula:C19H20ClNO6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:425.88
  • AGN 205327

    CAS:
    <p>AGN 205327 is a potent synthetic RAR agonist,showing selective RAR activation without RXR inhibition for retinoid research.</p>
    Formula:C24H26N2O3
    Purity:99.45% - 99.71%
    Color and Shape:Solid
    Molecular weight:390.47
  • HF51116

    CAS:
    <p>HF51116 blocks XCR4, hinders SDF-1α cell effects &amp; HIV-1; potential for HIV, stem cells, cancer spread.</p>
    Formula:C29H46N8O
    Color and Shape:Solid
    Molecular weight:522.73
  • CC214-2

    CAS:
    <p>CC214-2: strong dual mTORC1/2 inhibitor, blocks autophagy, may shorten TB duration.</p>
    Formula:C20H25N5O3
    Color and Shape:Solid
    Molecular weight:383.44
  • AS1708727

    CAS:
    <p>AS1708727 inhibits Foxo1, reducing blood sugar and triglycerides by altering gene expression.</p>
    Formula:C24H24Cl2N2O2
    Color and Shape:Solid
    Molecular weight:443.37
  • Aliskiren fumarate

    CAS:
    <p>Oral renin inhibitor Aliskiren fumarate treats hypertension; IC50: 1.5 nM. Useful for cardiovascular and cancer cachexia research.</p>
    Formula:C34H57N3O10
    Color and Shape:Solid
    Molecular weight:667.83
  • Rimacalib

    CAS:
    <p>Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).</p>
    Formula:C22H23FN4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:394.44
  • Elliptinium acetate

    CAS:
    <p>Elliptinium acetate (NSC 264137), a cytotoxic DNA intercalator for cancer research, targets L1210 cells.</p>
    Formula:C20H20N2O3
    Color and Shape:Solid
    Molecular weight:336.38
  • SA72

    CAS:
    <p>SA72 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH).</p>
    Formula:C21H26N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:402.44
  • SX-517

    CAS:
    <p>SX-517 is a non-competitive dual antagonist of CXCR1/2, demonstrating anti-inflammatory effects, inhibits CXCL-1-induced Ca²⁺ flux.</p>
    Formula:C19H16BFN2O3S
    Color and Shape:Solid
    Molecular weight:382.22
  • TN-14003

    CAS:
    <p>TN-14003 is a synthetic antagonist 14-mer peptide inhibiting metastasis in an animal model.</p>
    Formula:C90H141N33O18S2
    Color and Shape:Solid
    Molecular weight:2037.42
  • RNF5 inhibitor inh-02

    CAS:
    <p>RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR cystic fibrosis (CF).</p>
    Formula:C23H20N4S
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:384.5
  • (S)-Hydroxychloroquine

    CAS:
    <p>(S)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine shows efficiently inhibits SARS-CoV-2 infection in vitro.</p>
    Formula:C18H26ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:335.87
  • IZCZ-3

    CAS:
    <p>IZCZ-3,antitumor activity. is a potent c-MYC transcription inhibitor.</p>
    Formula:C46H49N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:715.93
  • KRH-1636

    CAS:
    <p>KRH-1636: potent, selective CXCR4 antagonist; orally active; inhibits X4 HIV-1 by blocking viral entry and membrane fusion.</p>
    Formula:C32H37N7O2
    Color and Shape:Solid
    Molecular weight:551.68
  • Autophagy inducer 4

    CAS:
    <p>Autophagy inducer 4, a Magnolol-based Mannich derivative, is an anticancer agent that blocks cancer cell migration &amp; is 76x more toxic to T47D cells.</p>
    Formula:C32H37NO6
    Color and Shape:Solid
    Molecular weight:531.64
  • PX20606 trans racemate

    CAS:
    <p>PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).</p>
    Formula:C29H22Cl3NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:554.85
  • Antitumor agent-81

    CAS:
    <p>Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.</p>
    Formula:C19H19N7O3
    Color and Shape:Solid
    Molecular weight:393.4
  • MPM-1


    <p>MPM-1, a marine mimic, induces rapid necrotic-like death in cancer cells, disrupts autophagy, and causes lysosomal swelling.</p>
    Formula:C34H44F6N4O7
    Color and Shape:Solid
    Molecular weight:734.73
  • IT1t

    CAS:
    <p>IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.</p>
    Formula:C21H34N4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.65
  • Amsacrine

    CAS:
    <p>Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.</p>
    Formula:C21H19N3O3S
    Purity:99.2%
    Color and Shape:Yellow Crystalline Powder Solid
    Molecular weight:393.46
  • CUR5g

    CAS:
    <p>CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.</p>
    Formula:C22H20N2O2
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:344.41
  • Evogliptin

    CAS:
    <p>Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.</p>
    Formula:C19H26F3N3O3
    Color and Shape:Solid
    Molecular weight:401.42
  • ATG7-IN-3

    CAS:
    <p>ATG7-IN-3, or compound 18, is an ATG7 inhibitor with a 0.048 μM IC50, blocking autophagy and LC3B puncta in H4 cells.</p>
    Formula:C11H16N6O5S2
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:376.41
  • Xantocillin

    CAS:
    <p>Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.</p>
    Formula:C18H12N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:288.3
  • YM-155 hydrochloride

    CAS:
    <p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>
    Formula:C20H19ClN4O3
    Color and Shape:Solid
    Molecular weight:398.85
  • OSU-53

    CAS:
    <p>OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.</p>
    Formula:C25H24F3N3O6S2
    Color and Shape:Solid
    Molecular weight:583.6
  • CCT128930

    CAS:
    <p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>
    Formula:C18H20ClN5
    Purity:99.07% - 99.18%
    Color and Shape:Solid
    Molecular weight:341.84
  • FAAH inhibitor 1

    CAS:
    <p>FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.</p>
    Formula:C24H23N3O3S3
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:497.65
  • (Rac)-BL-918

    CAS:
    <p>(Rac)-BL-918 is the racemic form of BL-918. BL-918 is an effective activator of UNC-51-like kinase 1 (ULK1) (EC₅₀ = 24.14 nM), Parkinson's disease.</p>
    Formula:C23H15F8N3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:533.44
  • YOK-2204

    CAS:
    <p>YOK-2204 is a ligand for the p62-ZZ domain and activates p62-dependent selective autophagy. It is also applicable in the design of AUTOTACs.</p>
    Formula:C28H35NO4
    Color and Shape:Solid
    Molecular weight:449.58
  • MRT-68601 HCl

    CAS:
    <p>MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.</p>
    Formula:C25H34N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:450.58
  • FKBP51F67V-selective antagonist Ligand2

    CAS:
    <p>FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or</p>
    Formula:C43H56N2O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:760.91
  • TUN-92046

    CAS:
    <p>TUN-92046 is a permeable alpha-ketoglutarate analog that blocks harmful autophagy in cardiomyopathy.</p>
    Formula:C7H10O5
    Purity:95.48% - 98.58%
    Color and Shape:Solid
    Molecular weight:174.15
  • Glaucocalyxin B

    CAS:
    <p>Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).</p>
    Formula:C22H30O5
    Purity:99.13% - 99.35%
    Color and Shape:Solid
    Molecular weight:374.47
  • GPR35 agonist 1

    CAS:
    <p>GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).</p>
    Formula:C10H4BrN5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.07
  • VUF5834

    CAS:
    <p>VUF5834 is a full inverse agonist of CXCR3 N3.35A.</p>
    Formula:C31H41N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.69
  • LRRK2-IN-10

    CAS:
    <p>LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2</p>
    Formula:C20H15N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:341.37
  • PS372424

    CAS:
    <p>PS372424 is a specific agonist of human CXCR3, with anti-inflammatory activity.</p>
    Formula:C33H44N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:588.74
  • AZ10397767

    CAS:
    <p>AZ10397767: Potent CXCR2 blocker (IC50=1nM); lowers neutrophil infiltration in tumors in vitro/in vivo.</p>
    Formula:C15H14ClFN4O2S2
    Color and Shape:Solid
    Molecular weight:400.88
  • FR 167653 free base

    CAS:
    <p>FR 167653 is an oral p38 MAPK inhibitor for inflammation, trauma, ischemia relief; it suppresses TNF-α, IL-1β.</p>
    Formula:C24H18FN5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:427.43
  • ROC-325

    CAS:
    <p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>
    Formula:C28H27ClN4OS
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:503.06
  • Sulfosuccinimidyl oleate

    CAS:
    <p>Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.</p>
    Formula:C22H37NO7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:459.6
  • SRT3190

    CAS:
    <p>SRT3190 is an antagonist of CXCR2.</p>
    Formula:C18H23F2N5O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:475.53
  • Ipsalazide

    CAS:
    <p>Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.</p>
    Formula:C16H11N3Na2O6
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:387.25
  • SCH 546738

    CAS:
    <p>SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.</p>
    Formula:C23H31Cl2N7O
    Purity:98.67%
    Color and Shape:Solid
    Molecular weight:492.45
  • AL 8697

    CAS:
    <p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>
    Formula:C21H21F3N4O
    Purity:99.55% - 99.89%
    Color and Shape:Solid
    Molecular weight:402.41
  • (-)-Talarozole

    CAS:
    <p>(-)-Talarozole is a potent retinoic acid metabolism inhibitor.</p>
    Formula:C21H23N5S
    Color and Shape:Solid
    Molecular weight:377.51
  • AGN 205728

    CAS:
    <p>AGN 205728 is a potent and selective RARγ antagonist (Ki: 3 nM; IC95: 0.6 nM) and has no inhibition on RARα and RARβ.</p>
    Formula:C29H27NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:437.53
  • GSK3-IN-3

    CAS:
    <p>GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.</p>
    Formula:C24H35N3O4
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:429.55
  • FC131

    CAS:
    <p>CXCR4 antagonist</p>
    Formula:C36H47N11O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:729.83
  • Dinoprost

    CAS:
    <p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>
    Formula:C20H34O5
    Purity:97.94% - 98.04%
    Color and Shape:White To Off-White Crystalline Solid
    Molecular weight:354.48
  • ABTL-0812

    CAS:
    <p>ABTL-0812 induces endoplasmic reticulum (ER) stress-mediated autophagy, and with anti-cancer activity.</p>
    Formula:C18H32O3
    Color and Shape:Solid
    Molecular weight:296.44
  • K67

    CAS:
    <p>K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.</p>
    Formula:C29H30N2O7S2
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:582.69
  • (Rac)-AZD 6482

    CAS:
    <p>(Rac)-AZD 6482 is the racemate of AZD 6482. AZD 6482 is a potent and selective inhibitor of p110β (IC50 of 0.69 nM).</p>
    Formula:C22H24N4O4
    Color and Shape:Solid
    Molecular weight:408.45
  • SR-17398

    CAS:
    <p>SR-17398 is an inhibitor of Unc-51-Like Kinase 1 (ULK1) (IC50 = 22.4 uM).</p>
    Formula:C14H18N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:258.32
  • Autophagy inducer 3

    CAS:
    <p>Autophagy Inducer 3 triggers selective cancer cell death via autophagy, sparing healthy cells.</p>
    Formula:C24H43NO2
    Color and Shape:Solid
    Molecular weight:377.6
  • Evogliptin tartrate

    CAS:
    <p>Evogliptin tartrate: Oral DPP-4 inhibitor, may treat atherosclerosis and diabetes.</p>
    Formula:C23H32F3N3O9
    Color and Shape:Solid
    Molecular weight:551.51
  • AC-55649

    CAS:
    <p>AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.</p>
    Formula:C21H26O2
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:310.43
  • MDK-6983

    CAS:
    <p>MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.</p>
    Formula:C22H18Cl2N2O3
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:429.3
  • AMDE-1

    CAS:
    <p>AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.</p>
    Formula:C18H8ClF6N3
    Purity:90%
    Color and Shape:Solid
    Molecular weight:415.72
  • SB02024

    CAS:
    <p>SB02024 inhibits VPS34, boosts cGAS-STING, hinders autophagy, and shrinks breast cancer xenografts; enhances Sunitinib/Erlotinib efficacy.</p>
    Formula:C16H22F3N3O2
    Color and Shape:Solid
    Molecular weight:345.36
  • FAAH-IN-1

    CAS:
    <p>FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively.</p>
    Formula:C20H19ClN4OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.91
  • GPP78

    CAS:
    <p>GPP78: Strong Nampt inhibitor, IC50 3.0 nM, depletes NAD. Kills SH-SY5Y cells, IC50 3.8 nM via autophagy. Anti-cancer and anti-inflammatory.</p>
    Formula:C27H29N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:439.55
  • 3HOI-BA-01

    CAS:
    <p>3HOI-BA-01 is a mammalian targeting effective rapamycin activation inhibitor.</p>
    Formula:C19H15NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:337.33
  • rac-NBI-74330

    CAS:
    <p>rac-NBI-74330 is an effective and selective CXCR3 antagonist.</p>
    Formula:C32H27F4N5O3
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:605.58
  • ACT-660602

    CAS:
    <p>ACT-660602: Oral CXCR3 blocker, T-cell migration inhibitor, effective in acute lung injury models, potential for autoimmune research. IC50: 204 nM.</p>
    Formula:C20H20F6N8OS
    Color and Shape:Solid
    Molecular weight:534.48
  • DK-1-49

    CAS:
    <p>DK-1-49 is an autophagonizer. It causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles.</p>
    Formula:C28H31N5O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.71
  • AMG 487 (S-enantiomer)

    CAS:
    <p>AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.</p>
    Formula:C32H28F3N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.59
  • SR12418

    CAS:
    <p>SR12418 is a specific synthetic ligand for REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. inhibits IL-17A expression in EL4 cells.</p>
    Formula:C31H30FNO3
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:483.57
  • VUF10132

    CAS:
    <p>VUF10132 is a full inverse CXCR3 N3.35A agonist.</p>
    Formula:C19H13BrCl4N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:523.03
  • (R)-Hydroxychloroquine

    CAS:
    <p>(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine is an agent of synthetic antimalarial.</p>
    Formula:C18H26ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:335.87
  • AC-73

    CAS:
    <p>AC-73, an oral CD147 inhibitor, blocks ERK1/2/STAT3/MMP-2 pathway, reducing liver cancer progression and leukemia cell growth.</p>
    Formula:C21H21NO2
    Purity:98.95%
    Color and Shape:Solid
    Molecular weight:319.4
  • Atg4B-IN-2

    CAS:
    <p>Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.</p>
    Formula:C21H30O3
    Purity:98.86%
    Color and Shape:Solid
    Molecular weight:330.46
  • GC7 Sulfate

    CAS:
    <p>GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.</p>
    Formula:C8H22N4O4S
    Purity:99.85% - >99.99%
    Color and Shape:Solid
    Molecular weight:270.35
  • NUCC-390

    CAS:
    <p>NUCC-390, a novel small-molecule CXCR4 receptor agonist, selectively induces CXCR4 receptor internalization while acting antagonistically to AMD3100.</p>
    Formula:C23H33N5O
    Purity:97.08%
    Color and Shape:Solid
    Molecular weight:395.54
  • Rosolutamide

    CAS:
    <p>Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.</p>
    Formula:C28H32O6
    Purity:95.48% - 99.15%
    Color and Shape:Solid
    Molecular weight:464.55
  • Apostatin-1

    CAS:
    <p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>
    Formula:C19H27N3OS
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:345.5
  • CCT020312

    CAS:
    <p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>
    Formula:C31H30Br2N4O2
    Purity:98.63%
    Color and Shape:Solid
    Molecular weight:650.4
  • CP-312

    CAS:
    <p>CP-312 activates antioxidant defense, induces HMOX1, and shields human iPSC-derived cardiomyocytes from oxidative stress.</p>
    Formula:C16H12ClN3OS2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:361.87
  • Acetazolamide sodium

    CAS:
    <p>Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA) IX inhibitor used for indications such as epilepsy and altitude sickness.</p>
    Formula:C4H5N4NaO3S2
    Purity:99.71% - 99.87%
    Color and Shape:Solid
    Molecular weight:244.23
  • MAPK13-IN-1

    CAS:
    <p>MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).</p>
    Formula:C20H23N5O2
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:365.43