Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1459 products of "Autophagy"
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TAK-779
CAS:<p>TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).</p>Formula:C33H39ClN2O2Purity:99.21%Color and Shape:SolidMolecular weight:531.13Polyphyllin I
CAS:<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Formula:C44H70O16Purity:98% - 99.5%Color and Shape:SolidMolecular weight:855.02JMS-17-2
CAS:<p>JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).</p>Formula:C25H26ClN3OPurity:98.7% - 99.44%Color and Shape:SolidMolecular weight:419.95TC14012 acetate
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM.Formula:C92H144N34O21S2Purity:98.33% - 99.71%Color and Shape:SolidMolecular weight:2126.47MSX-130
CAS:<p>MSX-130 is CXCR4 Antagonist.</p>Formula:C36H26N4Purity:99.19%Color and Shape:SolidMolecular weight:514.62SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Formula:C18H23F2N5O4S2Purity:99.65% - 99.92%Color and Shape:SolidMolecular weight:475.53Plerixafor
CAS:<p>Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.</p>Formula:C28H54N8Purity:99.17% - >99.99%Color and Shape:SolidMolecular weight:502.78AZD-5069
CAS:<p>AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).</p>Formula:C18H22F2N4O5S2Purity:98.38% - 98.63%Color and Shape:SolidMolecular weight:476.52Plerixafor octahydrochloride
CAS:<p>Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.</p>Formula:C28H62Cl8N8Purity:98.01% - 99.79%Color and Shape:SolidMolecular weight:794.46SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Formula:C19H14BF4N3O4SPurity:98.19% - 99.61%Color and Shape:SolidMolecular weight:467.2Isobavachalcone
CAS:<p>Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in</p>Formula:C20H20O4Purity:98% - 99.76%Color and Shape:SolidMolecular weight:324.37HG-10-102-01
CAS:<p>HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).</p>Formula:C17H20ClN5O3Purity:99.59%Color and Shape:SolidMolecular weight:377.83Lucanthone
CAS:<p>Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).</p>Formula:C20H24N2OSPurity:99.92%Color and Shape:Yellow Crystals From Alcohol SolidMolecular weight:340.48Pennogenin 3-O-β-chacotrioside
CAS:<p>Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.</p>Formula:C45H72O17Purity:99.69% - 99.77%Color and Shape:SolidMolecular weight:885.04RITA
CAS:<p>RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.</p>Formula:C14H12O3S2Purity:98.49% - 99.55%Color and Shape:SolidMolecular weight:292.374EGI-1
CAS:<p>4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).</p>Formula:C18H12Cl2N4O4SPurity:96.8% - 99.12%Color and Shape:SolidMolecular weight:451.28Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:97.79% - >99.99%Color and Shape:Yellow SolidMolecular weight:384.24CZC-25146 hydrochloride
CAS:<p>CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.</p>Formula:C22H26ClFN6O4SPurity:98.76%Color and Shape:SolidMolecular weight:525Danshensu
CAS:<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Formula:C9H10O5Purity:98.4% - 99.74%Color and Shape:SolidMolecular weight:198.17SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purity:99.47% - 99.92%Color and Shape:SolidMolecular weight:402.91
