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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • (R,R)-CXCR2-IN-2
    Targetmol
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    (R,R)-CXCR2-IN-2

    CAS:
    <p>'(R,R)-CXCR2-IN-2 is a brain-penetrating diastereoisomer and CXCR2 antagonist with pIC50 of 9 (Tango) and 6.8 (HWB Gro-α/CD11b).'</p>
    Formula:C18H23ClN2O5S
    Color and Shape:Solid
    Molecular weight:414.9

    Ref: TM-T36443

  • TIQ-15
    Targetmol
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    TIQ-15

    CAS:
    <p>TIQ-15 is an effective and selective CXCR4 antagonist. It has good drug-like properties.</p>
    Formula:C23H32N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:364.53

    Ref: TM-T24886

  • p38 MAPK-IN-1
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    p38 MAPK-IN-1

    CAS:
    <p>p38 MAPK-IN-1 is a novel selective p38 MAPK inhibitor with high potency, which reduces inflammatory responses by inhibiting LPS-induced TNF-α production.</p>
    Formula:C21H14F2N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.35

    Ref: TM-T16424

  • CXCR2 antagonist 3
    Targetmol
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    CXCR2 antagonist 3

    CAS:
    <p>Compound 11h, a CXCR2 antagonist, inhibits neutrophil/MDSCs and boosts CD3+ T cells in Pan02 tumors.</p>
    Formula:C17H15FN2O4S
    Color and Shape:Solid
    Molecular weight:362.38

    Ref: TM-T61356

  • (±)-AMG 487
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    (±)-AMG 487

    <p>AMG 487 is an effective and selective antagonist of chemokine receptor 3.</p>
    Formula:C32H28F3N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.59

    Ref: TM-T22477

  • BPO-27 racemate
    Targetmol
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    BPO-27 racemate

    CAS:
    <p>BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.</p>
    Formula:C26H18BrN3O6
    Purity:97.67% - 98.86%
    Color and Shape:Solid
    Molecular weight:548.34

    Ref: TM-T10591

  • Ladarixin Sodium
    Targetmol
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    Ladarixin Sodium

    CAS:
    <p>Ladarixin Sodium, an Chemokine CXCR antagonist, is used potentially for the treatment of type I diabetes.</p>
    Formula:C11H12F3NNaO6S2
    Color and Shape:Solid
    Molecular weight:398.32

    Ref: TM-T27791

  • SR10067
    Targetmol
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    SR10067

    CAS:
    <p>SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.</p>
    Formula:C31H31NO3
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:465.58

    Ref: TM-T12998

  • Acitretin sodium
    Targetmol
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    Acitretin sodium

    CAS:
    <p>Acitretin sodium is a second-generation, systemic retinoid. It is also has been used in the treatment of psoriasis.</p>
    Formula:C21H26NaO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:349.42

    Ref: TM-T22548

  • AGN 194078
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    AGN 194078

    CAS:
    <p>AGN 194078 is a selective RARα agonist (Kd: 3 nM; EC50: 112 nM).</p>
    Formula:C22H23F2NO4
    Color and Shape:Solid
    Molecular weight:403.42

    Ref: TM-T10265

  • Pentixafor
    Targetmol
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    Pentixafor

    CAS:
    <p>Pentixafor is a peptide that selectively targets the CXCR4 receptor and can be labeled with Gallium-68 (68Ga) for visualization using positron emission</p>
    Formula:C60H80N14O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1221.36

    Ref: TM-T79070

  • Cisd2 agonist 1
    Targetmol
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    Cisd2 agonist 1

    CAS:
    <p>Cisd2 agonist 1 is a CISD2) agonist (EC50: 34 nM) with potential anticancer activity and can be used to study non-alcoholic fatty liver disease (NAFLD).</p>
    Formula:C14H13FN2O3S
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:308.33

    Ref: TM-T78093

  • AGN 194310
    Targetmol
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    AGN 194310

    CAS:
    <p>AGN 194310 (VTP-194310) is retinioic acid receptors (RARs) pan-antagonist. The Kd values of 3 nM, 2 nM, 5 nM for RARα, RARβ, RARγ, respectively[1][2].</p>
    Formula:C28H24O2S
    Color and Shape:Solid
    Molecular weight:424.55

    Ref: TM-T14143

  • ATG12-ATG3 inhibitor 1
    Targetmol
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    ATG12-ATG3 inhibitor 1

    CAS:
    <p>ATG12-ATG3 Inhibitor 1 (compound 189) serves as a potent inhibitor of autophagy [1].</p>
    Formula:C18H17NO3S
    Color and Shape:Solid
    Molecular weight:327.4

    Ref: TM-T84819

  • EACC
    Targetmol
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    EACC

    CAS:
    <p>EACC inhibits Stx17, blocking autophagosome-lysosome fusion, and is a reversible autophagy inhibitor.</p>
    Formula:C13H11N3O6S2
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:369.37

    Ref: TM-T11142

  • NUCC-390 dihydrochloride (1060524-97-1 free base)
    Targetmol
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    NUCC-390 dihydrochloride (1060524-97-1 free base)

    <p>NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor.</p>
    Formula:C23H35Cl2N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.46

    Ref: TM-T12269L

  • SLLN-15
    Targetmol
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    SLLN-15

    CAS:
    <p>SLLN-15: oral, potent autophagy enhancer; targets macroautophagy in TNBC.</p>
    Formula:C19H23N7Se2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:507.35

    Ref: TM-T13889

  • CXCR2 antagonist 2
    Targetmol
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    CXCR2 antagonist 2

    CAS:
    <p>CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunotherapy with an IC 50 value of 95 nM.</p>
    Formula:C17H17FN2O4S
    Color and Shape:Solid
    Molecular weight:364.39

    Ref: TM-T61386

  • SAFit2
    Targetmol
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    SAFit2

    CAS:
    <p>SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51).Cost-effective and quality-assured</p>
    Formula:C46H62N2O10
    Purity:98.16% - >99.99%
    Color and Shape:Solid
    Molecular weight:802.99

    Ref: TM-T16836

  • PHY34
    Targetmol
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    PHY34

    CAS:
    <p>PHY34 inhibits autophagy at nanomolar potency, with anti-tumor effects on HGSOC in vivo.</p>
    Formula:C30H30O12
    Purity:98.71%
    Color and Shape:Solid
    Molecular weight:582.55

    Ref: TM-T37376