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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • Ponatinib-d8
    Targetmol
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    Ponatinib-d8

    CAS:
    <p>Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).</p>
    Formula:C29H27F3N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:540.61

    Ref: TM-T12521

  • CymitQuimica logo
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    Anti-LRRK2 Antibody (1C773)

    <p>Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.</p>
    Color and Shape:Odour Liquid

    Ref: TM-TMAH-00706

  • Tetrahydrocurcumin D6
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    Tetrahydrocurcumin D6

    CAS:
    <p>Tetrahydrocurcumin D6 is a deuterium labeled Tetrahydrocurcumin. Tetrahydrocurcumin displays inhibitory activity for CYP2C9 and CYP3A4.</p>
    Formula:C21H24O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.45

    Ref: TM-T13135

  • Manzamine A
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    Manzamine A

    CAS:
    <p>Manzamine A, from marine sponges, blocks GSK-3, halts cancer growth, prevents bacterial infections, and reduces tau phosphorylation.</p>
    Formula:C36H44N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:548.775

    Ref: TM-T27977

  • PS372424 hydrochloride
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    PS372424 hydrochloride

    CAS:
    <p>PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.</p>
    Formula:C33H45ClN6O4
    Purity:95.03%
    Color and Shape:Solid
    Molecular weight:625.2

    Ref: TM-T64661

  • Idelalisib D5
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    Idelalisib D5

    CAS:
    <p>Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ.</p>
    Formula:C22H18FN7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:420.45

    Ref: TM-T11610

  • Ladarixin
    Targetmol
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    Ladarixin

    CAS:
    <p>Ladarixin (DF 2156A free base) is an orally active, non-competitive CXCR1/CXCR2 allosteric inhibitor that suppresses AKT, NF-κB, and angiogenesis.</p>
    Formula:C11H12F3NO6S2
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:375.34

    Ref: TM-T32533

  • ACT-1004-1239
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    ACT-1004-1239

    CAS:
    <p>ACT-1004-1239 is a CXCR7 antagonist with immunomodulatory and myelination-promoting effects, used for research on inflammatory demyelinating diseases.</p>
    Formula:C27H28F2N6O3
    Purity:98.31%
    Color and Shape:Solid
    Molecular weight:522.55

    Ref: TM-T39665

  • Curcumin-d6
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    Curcumin-d6

    CAS:
    <p>Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-a</p>
    Formula:C21H20O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:374.422

    Ref: TM-T10901

  • Levomepromazine
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    Levomepromazine

    CAS:
    <p>Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.</p>
    Formula:C19H24N2OS
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:328.47

    Ref: TM-T15743

  • ATI-2341
    Targetmol
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    ATI-2341

    CAS:
    <p>ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.</p>
    Formula:C104H178N26O25S2
    Color and Shape:Solid
    Molecular weight:2256.82

    Ref: TM-T6764

  • Motixafortide
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    Motixafortide

    CAS:
    <p>Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).</p>
    Formula:C97H144FN33O19S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2159.52

    Ref: TM-T14665

  • CXCR2 antagonist 8
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    CXCR2 antagonist 8

    CAS:
    <p>CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.</p>
    Formula:C14H13N3O5
    Color and Shape:Solid
    Molecular weight:303.27

    Ref: TM-T60696

  • THZ-P1-2
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    THZ-P1-2

    CAS:
    <p>THZ-P1-2 is a PI5P4K inhibitor with anti-leukemic activity and can be used in the study of leukemia.</p>
    Formula:C31H29N7O2
    Color and Shape:Solid
    Molecular weight:531.61

    Ref: TM-T39459

  • Rosuvastatin Sodium
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    Rosuvastatin Sodium

    CAS:
    <p>Rosuvastatin Sodium: HMGCR inhibitor, blocks hERG (IC50: 11 nM, 195 nM), reduces hERG expression, hinders Hsp70-hERG interaction.</p>
    Formula:C22H27FN3NaO6S
    Color and Shape:Solid
    Molecular weight:503.52

    Ref: TM-T63430

  • Loperamide-d6 hydrochloride
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    Loperamide-d6 hydrochloride

    CAS:
    <p>Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.</p>
    Formula:C29H34Cl2N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:519.54

    Ref: TM-T11867

  • Br-DAPI
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    Br-DAPI

    CAS:
    <p>IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.</p>
    Formula:C16H14BrN5
    Purity:100%
    Color and Shape:Solid
    Molecular weight:356.22

    Ref: TM-T39967

  • OR-1855
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    OR-1855

    CAS:
    <p>OR-1855 is an active Levosimendan metabolite, has effect on human myometrial contractility.</p>
    Formula:C11H13N3O
    Purity:98%
    Color and Shape:Pale Yellow Solid
    Molecular weight:203.24

    Ref: TM-T13806

  • Aliskiren
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    Aliskiren

    CAS:
    <p>Aliskiren (CGP 60536) is a renin inhibitor (IC50: 1.5 nM) with antihypertensive activity and is used in the treatment of various cardiovascular diseases.</p>
    Formula:C30H53N3O6
    Purity:97.02%
    Color and Shape:Solid
    Molecular weight:551.76

    Ref: TM-T22233

  • CymitQuimica logo
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    Peptide R TFA

    <p>Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.</p>
    Formula:C39H57N13O8S2·xC2HF3O2
    Color and Shape:Solid
    Molecular weight:900.08 (free base)

    Ref: TM-TP3108

  • Omeprazole-d3
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    Omeprazole-d3

    CAS:
    <p>Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)</p>
    Formula:C17H19N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.44

    Ref: TM-T12308

  • IKK 16 hydrochloride
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    IKK 16 hydrochloride

    CAS:
    <p>IKK 16 hydrochloride, a potent IKK1/2 and LRRK2 inhibitor, IC50s: 40-200 nM and 50 nM respectively.</p>
    Formula:C28H30ClN5OS
    Color and Shape:Solid
    Molecular weight:520.09

    Ref: TM-T15557

  • Pemetrexed disodium heptahydrate
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    Pemetrexed disodium heptahydrate

    CAS:
    <p>Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits TS, DHFR and GARFT, inhibits precursor purine and pyrimidine nucleotides.</p>
    Formula:C20H33N5Na2O13
    Purity:99.783%
    Color and Shape:Solid
    Molecular weight:597.49

    Ref: TM-T66032

  • Brivanib
    Targetmol
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    Brivanib

    CAS:
    <p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but &gt;240-fold against</p>
    Formula:C19H19FN4O3
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:370.38

    Ref: TM-T6036

  • Cediranib maleate
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    Cediranib maleate

    CAS:
    <p>Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.</p>
    Formula:C29H31FN4O7
    Color and Shape:Solid
    Molecular weight:566.58

    Ref: TM-T2500L

  • Resveratrol analog 1
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    Resveratrol analog 1

    CAS:
    <p>Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.</p>
    Formula:C14H11FO2
    Purity:98.42%
    Color and Shape:Solid
    Molecular weight:230.23

    Ref: TM-T12708

  • Rupatadine
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    Rupatadine

    CAS:
    <p>Rupatadine (UR-12592, rupatadine) is a potent and orally available dual antagonist of PAF and histamine H1 receptors ,allergic and anti-inflammatory.</p>
    Formula:C26H26ClN3
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:415.96

    Ref: TM-T36618

  • Metformin-d6 hydrochloride
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    Metformin-d6 hydrochloride

    CAS:
    <p>Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.</p>
    Formula:C4H12ClN5
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:171.66

    Ref: TM-T73712

  • Pyrazinamide-d3
    Targetmol
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    Pyrazinamide-d3

    CAS:
    <p>Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.</p>
    Formula:C5D3H2N3O
    Color and Shape:Solid
    Molecular weight:126.13

    Ref: TM-TMIJ-0310

  • Dexamethasone-d5
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    Dexamethasone-d5

    CAS:
    <p>Dexamethasone-d5 is a deuterated compound of Dexamethasone.</p>
    Formula:C22H24D5FO5
    Color and Shape:Solid
    Molecular weight:397.49

    Ref: TM-TMIH-0186

  • Afatinib D6
    Targetmol
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    Afatinib D6

    CAS:
    <p>Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.</p>
    Formula:C24H25ClFN5O3
    Color and Shape:Solid
    Molecular weight:491.98

    Ref: TM-T10256

  • V-9302 hydrochloride
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    V-9302 hydrochloride

    CAS:
    <p>V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5.</p>
    Formula:C34H39ClN2O4
    Purity:97.31%
    Color and Shape:Solid
    Molecular weight:575.14

    Ref: TM-T40064

  • Nilotinib-d6
    Targetmol
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    Nilotinib-d6

    CAS:
    <p>Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.</p>
    Formula:C28H22F3N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:535.55

    Ref: TM-T12224

  • Megestrol Acetate-d3
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    Megestrol Acetate-d3

    CAS:
    <p>Megestrol Acetate-d3 is a deuterated compound of Megestrol Acetate. Megestrol Acetate has a CAS number of 595-33-5. Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.</p>
    Formula:C24H29D3O4
    Color and Shape:Solid
    Molecular weight:387.53

    Ref: TM-TMIJ-0025

  • Silibinin-d3
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    Silibinin-d3

    <p>Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.</p>
    Formula:C25H22O10
    Color and Shape:Solid
    Molecular weight:485.46

    Ref: TM-TMIH-0521

  • Isorhapontigenin
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    Isorhapontigenin

    CAS:
    <p>Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.</p>
    Formula:C15H14O4
    Purity:98.49% - 99.85%
    Color and Shape:Off White Crystals Power
    Molecular weight:258.27

    Ref: TM-T3814

  • Valproic Acid
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    Valproic Acid

    CAS:
    <p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>
    Formula:C8H16O2
    Purity:97.78% - 99%
    Color and Shape:Colourless To Pale Yellow Liquid Viscous
    Molecular weight:144.21

    Ref: TM-T7064

  • Ginkgolide K
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    Ginkgolide K

    CAS:
    <p>Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.</p>
    Formula:C20H22O9
    Purity:99.44% - 99.72%
    Color and Shape:Solid
    Molecular weight:406.38

    Ref: TM-T8200

  • Momelotinib
    Targetmol
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    Momelotinib

    CAS:
    <p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>
    Formula:C23H22N6O2
    Purity:97.47% - 99.56%
    Color and Shape:Solid
    Molecular weight:414.46

    Ref: TM-T1849

  • Clematichinenoside AR
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    Clematichinenoside AR

    CAS:
    <p>Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.</p>
    Formula:C82H134O43
    Purity:99.04% - 99.69%
    Color and Shape:Solid
    Molecular weight:1807.92

    Ref: TM-TN1507

  • Tanespimycin
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    Tanespimycin

    CAS:
    <p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>
    Formula:C31H43N3O8
    Purity:99.07% - 99.83%
    Color and Shape:Dark Purple Solid
    Molecular weight:585.69

    Ref: TM-T6290

  • Selenomethionine
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    Selenomethionine

    CAS:
    <p>DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.</p>
    Formula:C5H11NO2Se
    Purity:98% - 99.95%
    Color and Shape:Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals Solid
    Molecular weight:196.11

    Ref: TM-T1658

  • Dimethyl fumarate
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    Dimethyl fumarate

    CAS:
    <p>Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.</p>
    Formula:C6H8O4
    Purity:90.51% - >99.99%
    Color and Shape:White To Off-White Powder White Crystalline Powder
    Molecular weight:144.13

    Ref: TM-T0492

  • ABT-751
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    ABT-751

    CAS:
    <p>ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.</p>
    Formula:C18H17N3O4S
    Purity:98.84% - 99.50%
    Color and Shape:Solid
    Molecular weight:371.41

    Ref: TM-T1758

  • GNE0877
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    GNE0877

    CAS:
    <p>GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).</p>
    Formula:C14H16F3N7
    Purity:98.01% - 99.97%
    Color and Shape:Solid
    Molecular weight:339.32

    Ref: TM-T6031

  • Autophinib
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    Autophinib

    CAS:
    <p>Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and</p>
    Formula:C14H11ClN6O3
    Purity:99.25% - 99.41%
    Color and Shape:Solid
    Molecular weight:346.73

    Ref: TM-T4219

  • Corynoxine
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    Corynoxine

    CAS:
    <p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>
    Formula:C22H28N2O4
    Purity:96.83% - 99.93%
    Color and Shape:Solid
    Molecular weight:384.47

    Ref: TM-T5S0658

  • STO-609
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    STO-609

    CAS:
    <p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>
    Formula:C19H10N2O3
    Purity:97.14% - 98.8%
    Color and Shape:Solid
    Molecular weight:314.29

    Ref: TM-T3546

  • CHIR-99021
    Targetmol
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    CHIR-99021

    CAS:
    <p>View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.</p>
    Formula:C22H18Cl2N8
    Purity:97.94% - ≥95%
    Color and Shape:Solid
    Molecular weight:465.34

    Ref: TM-T2310

  • Bergapten
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    Bergapten

    CAS:
    <p>Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.</p>
    Formula:C12H8O4
    Purity:99.48% - ≥95%
    Color and Shape:Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)
    Molecular weight:216.19

    Ref: TM-T2143