Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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Polyphemusin II-Derived Peptide
CAS:T140, a Polyphemusin II-derived peptide, inhibits HIV-1 entry and blocks anti-CXCR4 antibody (12G5) binding.Formula:C90H141N33O18S2Color and Shape:SolidMolecular weight:2037.42Peptide R
CAS:Peptide R, a cyclic CXCR4 antagonist, remodels tumor stroma, aiding cancer research.Formula:C39H59N13O8S2Color and Shape:SolidMolecular weight:902.1Erlotinib-13C6
CAS:Erlotinib-13C6 (CP-358774-13C6), a 13C-labeled direct EGFR inhibitor, IC50: 2 nM.Formula:C22H23N3O4Color and Shape:SolidMolecular weight:399.397CXCL-CXCR1/2-IN-1
CAS:CXCL-CXCR1/2-IN-1 is an ELR+CXCL-CXCR1/2 pathway inhibitor with anticancer activity and can be used in the study of cardiovascular disease.Formula:C14H8Cl2N4O3SPurity:99.4%Color and Shape:SoildMolecular weight:383.21Microcolin H
CAS:Microcolin H, a marine lipopeptide and phosphatidylinositol transfer protein ligand, targets PITPα/β. It enhances the conversion of LC3I to LC3II and decreases p62 levels in cancer cells, inducing autophagy cell death (Autophagy). Furthermore, Microcolin H effectively inhibits tumor growth and exhibits anti-proliferative activity in nude mouse subcutaneous tumor models [1].Formula:C38H63N5O9Color and Shape:SolidMolecular weight:733.93PI3K-AKT-mTOR Compound Library
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved withColor and Shape:Odour SolidRef: TM-L1300
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireBeclin1-Bcl-2 interaction inhibitor 1
Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1].Color and Shape:Odour SolidPBA-1105b
CAS:PBA-1105b, a longer PEGylated derivative of PBA-1105, is an autophagy-targeting chimeric compound (AUTOTAC) that can induce self-oligomerization of p62. It enhances the autophagic flux of Ub-bound aggregates.Formula:C47H64N2O10Color and Shape:SolidMolecular weight:817.02CX4338
CAS:CX4338 is a CXCL8-mediated chemotaxis inhibitor.Formula:C22H24N2OSColor and Shape:SolidMolecular weight:364.50Olaparib-d5
CAS:Olaparib D5 is a deuterium labeled Olaparib. Olaparib is a potent and oral inhibitor of PARP.Formula:C24H23FN4O3Purity:98%Color and Shape:SolidMolecular weight:439.49Aliskiren
CAS:Aliskiren (CGP 60536) is a renin inhibitor (IC50: 1.5 nM) with antihypertensive activity and is used in the treatment of various cardiovascular diseases.Formula:C30H53N3O6Purity:97.02%Color and Shape:SolidMolecular weight:551.76Ref: TM-T22233
1mg34.00€5mg70.00€10mg100.00€25mg141.00€50mg177.00€100mg268.00€200mg398.00€1mL*10mM (DMSO)85.00€Heparin Lithium
CAS:Heparin Lithium salt is an anticoagulant that reversibly binds to ATIII and enhances its inhibitory effect on coagulation factor(thrombin and factor Xa).Formula:C14H25NO20S3Color and Shape:SolidMolecular weight:623.01321Omeprazole-d3
CAS:Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)Formula:C17H19N3O3SPurity:98%Color and Shape:SolidMolecular weight:348.44Imatinib D4
CAS:Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.Formula:C29H31N7OPurity:98%Color and Shape:SolidMolecular weight:497.63Bexarotene D4
CAS:Bexarotene D4 is a deuterium-labeled Bexarotene (LGD1069). Bexarotene is a selective RXR agonist used in the treatment of cutaneous T-cell lymphoma.Formula:C24H28O2Purity:98%Color and Shape:SolidMolecular weight:352.5Trimetazidine
CAS:Trimetazidine is a antianginal agent that selectively inhibits the mitochondrial enzyme LC 3-KAT, thereby preventing β-oxidation of free fatty acids.Formula:C14H22N2O3Purity:99.9%Color and Shape:Hite Or Off-White Crystalline PowderMolecular weight:266.34Binimetinib-13C-d3
Binimetinib-13C-d3 (MEK162) is an isotopically labelled compound of Binimetinib.Binimetinib (ARRY-162) is a selective MEK1/2 inhibitor melanoma.Formula:C17H15BrF2N4O3Color and Shape:SolidMolecular weight:445.24LG100268
CAS:LG100268 is a selective, and oral RXR agonist，inducing transcriptional activation in adipocytes; inhibits keratin 17 increases PD-L1 expression.Formula:C24H29NO2Purity:99.83%Color and Shape:SolidMolecular weight:363.49Enzalutamide-d3
CAS:Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.Formula:C21H16F4N4O2SColor and Shape:SolidMolecular weight:467.45TRAF6 peptide TFA
TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA.Formula:C145H238N34O44·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3161.64 (free acid)Isoniazid-d4
CAS:Isoniazid-d4 is a deuterium isotope marker for Isoniazid.Isoniazid is a prodrug that must be activated by the bacterial peroxidase KatG, and is bactericidal.Formula:C6H3D4N3OColor and Shape:SolidMolecular weight:141.16Nilotinib-d6
CAS:Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.Formula:C28H22F3N7OPurity:98%Color and Shape:SolidMolecular weight:535.55Rapamycin-d3
CAS:Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).Formula:C51H79NO13Purity:98%Color and Shape:SolidMolecular weight:917.19Rapalink-1
CAS:Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.Formula:C91H138N12O24Purity:98%Color and Shape:SolidMolecular weight:1784.14ACT-1004-1239
CAS:ACT-1004-1239 is a CXCR7 antagonist with immunomodulatory and myelination-promoting effects, used for research on inflammatory demyelinating diseases.
Formula:C27H28F2N6O3Purity:98.31%Color and Shape:SolidMolecular weight:522.55Erlotinib-d6 hydrochloride
CAS:Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.Formula:C22H24ClN3O4Purity:98%Color and Shape:SolidMolecular weight:435.93Ponatinib-d8
CAS:Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Formula:C29H27F3N6OPurity:98%Color and Shape:SolidMolecular weight:540.61KN-93 hydrochloride
CAS:KN-93 hydrochloride is a reversible, competitive CaMKII inhibitor inducing reversible G1 arrest, supporting cell cycle and signaling pathway studies.Formula:C26H30Cl2N2O4SPurity:99.99%Color and Shape:SolidMolecular weight:537.5Levomepromazine
CAS:Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.Formula:C19H24N2OSPurity:99.15%Color and Shape:SolidMolecular weight:328.47ATI-2341
CAS:ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.Formula:C104H178N26O25S2Color and Shape:SolidMolecular weight:2256.82Rosuvastatin D3 Sodium
CAS:Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).Formula:C22H24D3FN3NaO6SPurity:98%Color and Shape:SolidMolecular weight:506.54Anti-LRRK2 Antibody (1C773)
Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.Color and Shape:Odour LiquidMotixafortide
CAS:Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).Formula:C97H144FN33O19S2Purity:98%Color and Shape:SolidMolecular weight:2159.52PS372424 hydrochloride
CAS:PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.Formula:C33H45ClN6O4Purity:95.03%Color and Shape:SolidMolecular weight:625.2Tetrahydrocurcumin D6
CAS:Tetrahydrocurcumin D6 is a deuterium labeled Tetrahydrocurcumin. Tetrahydrocurcumin displays inhibitory activity for CYP2C9 and CYP3A4.Formula:C21H24O6Purity:98%Color and Shape:SolidMolecular weight:378.45Ezetimibe-d4
CAS:Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activationFormula:C24H21F2NO3Purity:98%Color and Shape:White SolidMolecular weight:413.45Manzamine A
CAS:Manzamine A, from marine sponges, blocks GSK-3, halts cancer growth, prevents bacterial infections, and reduces tau phosphorylation.Formula:C36H44N4OPurity:98%Color and Shape:SolidMolecular weight:548.775(R)-BPO-27
CAS:(R)-BPO-27 is an orally active and potent ATP-competitive CFTR inhibitor (IC50: 4 nM) for the study of diarrhoea and polycystic kidney.Formula:C26H18BrN3O6Purity:99.1%Color and Shape:SolidMolecular weight:548.34Idelalisib D5
CAS:Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ.Formula:C22H18FN7OPurity:98%Color and Shape:SolidMolecular weight:420.45Desethyl chloroquine diphosphate
CAS:Desethyl chloroquine diphosphate is the active metabolite of Desethylchloroquine, an inhibitor of TLRs with antiplasmodial activity and inhibition of autophagy.Formula:C16H28ClN3O8P2Purity:99.72%Color and Shape:SolidMolecular weight:487.81Ladarixin
CAS:Ladarixin (DF 2156A free base) is an orally active, non-competitive CXCR1/CXCR2 allosteric inhibitor that suppresses AKT, NF-κB, and angiogenesis.Formula:C11H12F3NO6S2Purity:99.36%Color and Shape:SolidMolecular weight:375.34Curcumin-d6
CAS:Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-aFormula:C21H20O6Purity:98%Color and Shape:SolidMolecular weight:374.422Ambroxol hydrochloride (Standard)
CAS:Ambroxol hydrochloride (Standard) is the standard substance of Ambroxol hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.Formula:C13H18Br2N2O·HClMolecular weight:414.56Silibinin-d3
Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.Formula:C25H22O10Color and Shape:SolidMolecular weight:485.46Regorafenib-d3
CAS:Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.Formula:C21H15ClF4N4O3Purity:98%Color and Shape:SolidMolecular weight:485.83CXCR2 antagonist 8
CAS:CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.Formula:C14H13N3O5Color and Shape:SolidMolecular weight:303.27THZ-P1-2
CAS:THZ-P1-2 is a PI5P4K inhibitor with anti-leukemic activity and can be used in the study of leukemia.Formula:C31H29N7O2Color and Shape:SolidMolecular weight:531.61Ref: TM-T39459
1mg74.00€2mgTo inquire5mg160.00€10mg216.00€25mg349.00€50mg494.00€100mg692.00€200mg934.00€1mL*10mM (DMSO)182.00€Theophylline-d6
CAS:Theophylline-d6, an internal standard for theophylline quantification in GC/LC-MS, relaxes bronchial muscles and treats asthma/COPD.Formula:C7H2D6N4O2Color and Shape:SolidMolecular weight:186.2Br-DAPI
CAS:IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.Formula:C16H14BrN5Purity:100%Color and Shape:SolidMolecular weight:356.22OR-1855
CAS:OR-1855 is an active Levosimendan metabolite, has effect on human myometrial contractility.Formula:C11H13N3OPurity:98%Color and Shape:Pale Yellow SolidMolecular weight:203.24
