Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Cilengitide TFA
CAS:199807-35-7
Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.
Formula:
C29H41F3N8O9
Color and Shape:
Solid
Molecular weight:
702.68
Ref: TM-T6806
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Monday 18 Nov 2024
Ferrozine monosodium salt
CAS:69898-45-9
Ferrozine monosodium salt, a dye, forms a stable magenta complex with Fe2+ for iron spectrophotometry.
Formula:
C20H13N4NaO6S2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
492.46
Ref: TM-T66932
| 100mg | 41.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
Ammonium Chloride
CAS:12125-02-9
Ammonium chloride inhibits autophagy, regulates pH, can disrupt enzymes, and may hinder muscle mitochondrial function.
Formula:
ClH4N
Purity:
99%
Color and Shape:
Solid
Molecular weight:
53.49
Ref: TM-T64755
| 1g | 86.00 € | ||
| 500mg | 60.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
740 Y-P
CAS:1236188-16-1
740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.
Formula:
C141H222N43O39PS3
Purity:
98.3% - 99.87%
Color and Shape:
Solid
Molecular weight:
3270.7
Ref: TM-TQ0003
| 1mg | 97.00 € | ||
| 2mg | 135.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 876.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
SLF
CAS:195513-96-3
SLF is a synthetic ligand for FKBP12 and increases Ca2+ efflux and protein synthesis.
Formula:
C30H40N2O6
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
524.65
Ref: TM-T13888
| 2mg | 83.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
Bromobimane
CAS:71418-44-5
Bromobimane, non-fluorescent alone, becomes fluorescent with thiols; used to measure blood sulfide.
Formula:
C10H11BrN2O2
Purity:
97.1% - 98%
Color and Shape:
Solid
Molecular weight:
271.11
Ref: TM-T18929
| 5mg | 53.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
AICAR phosphate
CAS:681006-28-0
AICAR phosphate (Acadesine phosphate) is an AMPK activator, an inhibitor of autophagy, YAP and mitophagy, …
Formula:
C9H14N4O5·xH3O4P
Purity:
100%
Color and Shape:
Solid
Molecular weight:
356.23
Ref: TM-T14149
| 25mg | 53.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
GW406108X
CAS:1644443-92-4
GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.
Formula:
C20H11Cl2NO4
Color and Shape:
Solid
Molecular weight:
400.21
Ref: TM-T9207
| 2mg | 142.00 € | ||
| 5mg | 232.00 € | ||
| 10mg | 387.00 € | ||
| 1mL*10mM (DMSO) | 257.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
Brivanib
CAS:649735-46-6
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency …
Formula:
C19H19FN4O3
Purity:
98.87%
Color and Shape:
Solid
Molecular weight:
370.38
Ref: TM-T6036
| 1mg | 46.00 € | ||
| 2mg | 76.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 256.00 € | ||
| 50mg | 371.00 € | ||
| 100mg | 553.00 € | ||
| 200mg | 804.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
Gemcitabine elaidate
CAS:210829-30-4
Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an …
Formula:
C27H43F2N3O5
Color and Shape:
Solid
Molecular weight:
527.64
Ref: TM-T15378
| 2mg | 50.00 € | ||
| 5mg | 97.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
Resveratrol analog 1
CAS:861446-16-4
Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic …
Formula:
C14H11FO2
Purity:
98.42%
Color and Shape:
Solid
Molecular weight:
230.23
Ref: TM-T12708
| 1mg | 46.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
R1487 Hydrochloride
CAS:449808-64-4
R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.
Formula:
C19H19ClF2N4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
424.83
Ref: TM-T7162
| 2mg | 71.00 € | ||
| 5mg | 104.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
Saquinavir mesylate
CAS:149845-06-7
Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy
Formula:
C39H54N6O8S
Purity:
98%
Color and Shape:
White Or Pale Yellow Powder
Molecular weight:
766.9
Ref: TM-T8156
| 10mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
DMH-1
CAS:1206711-16-1
DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent …
Formula:
C24H20N4O
Purity:
98% - 99.92%
Color and Shape:
Solid
Molecular weight:
380.44
Ref: TM-T1942
| 5mg | 62.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 428.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
SP600125
CAS:129-56-6
SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 …
Formula:
C14H8N2O
Purity:
97.63% - 99.58%
Color and Shape:
Solid
Molecular weight:
220.23
Ref: TM-T3109
| 10mg | 48.00 € | ||
| 50mg | 52.00 € | ||
| 100mg | 80.00 € | ||
| 200mg | 90.00 € | ||
| 500mg | 144.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Pexmetinib
CAS:945614-12-0
Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.
Formula:
C31H33FN6O3
Purity:
98.41% - 99.66%
Color and Shape:
Solid
Molecular weight:
556.63
Ref: TM-T6934
| 2mg | 58.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 501.00 € | ||
| 100mg | 558.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
CAS:1383716-46-8
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor …
Formula:
C21H25N7O
Purity:
98.60%
Color and Shape:
Solid
Molecular weight:
391.47
Ref: TM-T7944
| 1mg | 66.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 389.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 735.00 € | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
XCT790
CAS:725247-18-7
XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).
Formula:
C23H13F9N4O3S
Purity:
99% - 99.74%
Color and Shape:
Solid
Molecular weight:
596.42
Ref: TM-T0593
| 5mg | 64.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 321.00 € | ||
| 100mg | 478.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
20-DEOXYINGENOL
CAS:54706-99-9
20-DEOXYINGENOL is a natual product.
Formula:
C20H28O4
Purity:
99.98% - ≥95%
Color and Shape:
Solid
Molecular weight:
332.43
Ref: TM-T5689
| 20mg | 125.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
U0126
CAS:109511-58-2
U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with …
Formula:
C18H16N6S2
Purity:
98%
Color and Shape:
White Solid
Molecular weight:
380.49
Ref: TM-T21332
| 1mg | 151.00 € | ||
| 5mg | 358.00 € | ||
| 10mg | 660.00 € | ||
| 25mg | 1,139.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
