Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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ML327
CAS:1883510-31-3
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition …
Formula:
C19H18N4O4
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
366.37
Ref: TM-T4252
| 1mg | 49.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 791.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Sitagliptin phosphate
CAS:654671-78-0
Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.
Formula:
C16H18F6N5O5P
Purity:
99.72% - 99.72%
Color and Shape:
White Solid
Molecular weight:
505.31
Ref: TM-T23358
| 50mg | 39.00 € | ||
| 100mg | 51.00 € | ||
| 200mg | 62.00 € | ||
| 500mg | 91.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Wortmannin
CAS:19545-26-7
Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.
Formula:
C23H24O8
Purity:
95.84% - 99.76%
Color and Shape:
White Solid
Molecular weight:
428.43
Ref: TM-T6283
| 1mg | 38.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Crizotinib hydrochloride
CAS:1415560-69-8
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of …
Formula:
C21H23Cl3FN5O
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
486.8
Ref: TM-T8399
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 98.00 € | ||
| 100mg | 135.00 € | ||
| 200mg | 168.00 € | ||
| 500mg | 222.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Danusertib
CAS:827318-97-8
Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.
Formula:
C26H30N6O3
Purity:
98% - 98.44%
Color and Shape:
White Powder
Molecular weight:
474.55
Ref: TM-T2094
| 1mg | 59.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 546.00 € | ||
| 100mg | 779.00 € | ||
| 500mg | 1,574.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
3-Methyladenine
CAS:5142-23-4
3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and …
Formula:
C6H7N5
Purity:
98.02% - 99.51%
Color and Shape:
Solid
Molecular weight:
149.15
Ref: TM-T1879
| 25mg | 41.00 € | ||
| 50mg | 52.00 € | ||
| 100mg | 87.00 € | ||
| 200mg | 135.00 € | ||
| 500mg | 247.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
WYC-209
CAS:2131803-90-0
WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets …
Formula:
C20H20N2O3S
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
368.45
Ref: TM-T5341
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 452.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Salirasib
CAS:162520-00-5
Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.
Formula:
C22H30O2S
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
358.54
Ref: TM-T6163
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 157.00 € | ||
| 100mg | 217.00 € | ||
| 200mg | 356.00 € | ||
| 500mg | 587.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Afatinib Dimaleate
CAS:850140-73-7
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR …
Formula:
C32H33ClFN5O11
Purity:
100% - 99.66%
Color and Shape:
Solid
Molecular weight:
718.08
Ref: TM-T1773
| 1g | 460.00 € | ||
| 5mg | 40.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 105.00 € | ||
| 100mg | 138.00 € | ||
| 200mg | 184.00 € | ||
| 500mg | 308.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
TA-02
CAS:1784751-19-4
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.
Formula:
C20H13F2N3
Purity:
99.35% - 99.79%
Color and Shape:
Solid
Molecular weight:
333.33
Ref: TM-T4646
| 5mg | 39.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 103.00 € | ||
| 50mg | 157.00 € | ||
| 100mg | 239.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Sepantronium bromide
CAS:781661-94-7
Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
Formula:
C20H19BrN4O3
Purity:
99.68% - 99.82%
Color and Shape:
Solid
Molecular weight:
443.26
Ref: TM-T2111
| 2mg | 39.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 146.00 € | ||
| 50mg | 251.00 € | ||
| 100mg | 412.00 € | ||
| 500mg | 910.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
LY294002
CAS:154447-36-6
LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 …
Formula:
C19H17NO3
Purity:
98% - 99.96%
Color and Shape:
Pale Yellow Solid
Molecular weight:
307.34
Ref: TM-T2008
| 5mg | 39.00 € | ||
| 10mg | 50.00 € | ||
| 50mg | 71.00 € | ||
| 100mg | 93.00 € | ||
| 200mg | 121.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
PFI-1
CAS:1403764-72-6
PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of …
Formula:
C16H17N3O4S
Purity:
97.21% - 98.59%
Color and Shape:
Solid
Molecular weight:
347.39
Ref: TM-T6222
| 5mg | 50.00 € | ||
| 10mg | 76.00 € | ||
| 25mg | 120.00 € | ||
| 50mg | 186.00 € | ||
| 100mg | 341.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
3'-Hydroxypterostilbene
CAS:475231-21-1
3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, …
Formula:
C16H16O4
Purity:
99.19% - 99.19%
Color and Shape:
Solid
Molecular weight:
272.3
Ref: TM-T2S2382
| 20mg | 97.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BIIB021
CAS:848695-25-0
BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).
Formula:
C14H15ClN6O
Purity:
98% - 99.82%
Color and Shape:
Solid
Molecular weight:
318.76
Ref: TM-T2286
| 5mg | 52.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 168.00 € | ||
| 100mg | 247.00 € | ||
| 200mg | 422.00 € | ||
| 500mg | 690.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Bexarotene
CAS:153559-49-0
Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of …
Formula:
C24H28O2
Purity:
98.12% - 99%
Color and Shape:
White Solid
Molecular weight:
348.48
Ref: TM-T6410
| 10mg | 35.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 67.00 € | ||
| 100mg | 88.00 € | ||
| 200mg | 119.00 € | ||
| 500mg | 243.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Sapanisertib
CAS:1224844-38-5
Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.
Formula:
C15H15N7O
Purity:
100% - 99.34%
Color and Shape:
Solid
Molecular weight:
309.33
Ref: TM-T1838
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 344.00 € | ||
| 500mg | 824.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Flavopiridol hydrochloride
CAS:131740-09-5
Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone …
Formula:
C21H21Cl2NO5
Purity:
98.87% - 99.88%
Color and Shape:
Solid
Molecular weight:
438.3
Ref: TM-T2615
| 5mg | 52.00 € | ||
| 10mg | 77.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
AGN 193109
CAS:171746-21-7
AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 …
Formula:
C28H24O2
Purity:
98.81% - 99.89%
Color and Shape:
Solid
Molecular weight:
392.49
Ref: TM-TQ0097
| 1mg | 67.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 231.00 € | ||
| 25mg | 463.00 € | ||
| 50mg | 674.00 € | ||
| 100mg | 916.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
GSK2578215A
CAS:1285515-21-0
GSK2578215A is a potent and selective LRRK2 kinase inhibitor.
Formula:
C24H18FN3O2
Purity:
97.93% - 99.94%
Color and Shape:
Solid
Molecular weight:
399.42
Ref: TM-T2240
| 5mg | 34.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 89.00 € | ||
| 50mg | 153.00 € | ||
| 100mg | 218.00 € | ||
| 200mg | 328.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
