Aurora Kinase
Aurora kinase inhibitors target the Aurora kinases, a family of serine/threonine kinases that play a critical role in the regulation of mitosis. These kinases are essential for proper chromosome alignment, segregation, and cytokinesis during cell division. Abnormal Aurora kinase activity can lead to uncontrolled cell proliferation and cancer. By inhibiting Aurora kinases, these compounds can induce cell cycle arrest and apoptosis in cancer cells, making them valuable tools in cancer research and therapy. At CymitQuimica, we offer a wide range of high-quality Aurora kinase inhibitors to support your research in cell cycle regulation, mitosis, and oncology.
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Ilorasertib
CAS:1227939-82-3
Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).
Formula:
C25H21FN6O2S
Purity:
96.17% - 98.03%
Color and Shape:
Solid
Molecular weight:
488.54
Ref: TM-TQ0059
| 1mg | 39.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 397.00 € | ||
| 200mg | 552.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Hesperadin
CAS:422513-13-1
Hesperadin(IC50=250 nM) effectively inhibits Aurora B.
Formula:
C29H32N4O3S
Purity:
98.04% - 99.44%
Color and Shape:
Solid
Molecular weight:
516.65
Ref: TM-T6532
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 193.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
CYC-116
CAS:693228-63-6
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is …
Formula:
C18H20N6OS
Purity:
96.6% - 97.59%
Color and Shape:
Solid
Molecular weight:
368.46
Ref: TM-T6458
| 2mg | 39.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 76.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 213.00 € | ||
| 100mg | 349.00 € | ||
| 500mg | 886.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).
Formula:
C25H20FN7O
Purity:
97.82%
Color and Shape:
Solid
Molecular weight:
453.47
Ref: TM-T8685
| 1mg | 85.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
MK-8745
CAS:885325-71-3
MK-8745 is a potent and selective Aurora A inhibitor.
Formula:
C20H19ClFN5OS
Purity:
98.94% - 99.31%
Color and Shape:
Solid
Molecular weight:
431.91
Ref: TM-T2471
| 5mg | 45.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 146.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
CCT 137690
CAS:1095382-05-0
CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM …
Formula:
C26H31BrN8O
Purity:
98.51% - 99.82%
Color and Shape:
Solid
Molecular weight:
551.48
Ref: TM-T2611
| 2mg | 55.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 474.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
SNS-314 Mesylate
CAS:1146618-41-8
SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition …
Formula:
C18H15ClN6OS2·CH4O3S
Purity:
99.92% - 99.92%
Color and Shape:
Solid
Molecular weight:
527.04
Ref: TM-T2617
| 2mg | 39.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 244.00 € | ||
| 100mg | 384.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
MLN8054
CAS:869363-13-3
MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 …
Formula:
C25H15ClF2N4O2
Purity:
98.07% - 98.26%
Color and Shape:
Solid
Molecular weight:
476.86
Ref: TM-T6315
| 1mg | 52.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 374.00 € | ||
| 100mg | 562.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
ZM-447439
CAS:331771-20-1
ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, …
Formula:
C29H31N5O4
Purity:
98.53% - 99.11%
Color and Shape:
Pale Yellow Solid
Molecular weight:
513.59
Ref: TM-T6077
| 5mg | 49.00 € | ||
| 10mg | 66.00 € | ||
| 50mg | 200.00 € | ||
| 100mg | 343.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
TAK-632
CAS:1228591-30-7
TAK-632 is a potent pan-Raf inhibitor.
Formula:
C27H18F4N4O3S
Purity:
98% - 98.92%
Color and Shape:
Solid
Molecular weight:
554.52
Ref: TM-T1886
| 5mg | 41.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 121.00 € | ||
| 100mg | 208.00 € | ||
| 200mg | 270.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Aurora kinase inhibitor-3
CAS:879127-16-9
Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase …
Formula:
C21H18F3N5O
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
413.4
Ref: TM-T5524
| 1mg | 77.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 186.00 € | ||
| 10mg | 294.00 € | ||
| 25mg | 494.00 € | ||
| 50mg | 702.00 € | ||
| 100mg | 926.00 € | ||
| 200mg | 1,295.00 € | ||
| 1mL*10mM (DMSO) | 212.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Danusertib
CAS:827318-97-8
Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.
Formula:
C26H30N6O3
Purity:
98% - 98.44%
Color and Shape:
White Powder
Molecular weight:
474.55
Ref: TM-T2094
| 1mg | 59.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 546.00 € | ||
| 100mg | 779.00 € | ||
| 500mg | 1,574.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
KW-2449
CAS:1000669-72-6
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora …
Formula:
C20H20N4O
Purity:
98.43% - 99.89%
Color and Shape:
Solid
Molecular weight:
332.4
Ref: TM-T2341
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 472.00 € | ||
| 500mg | 1,056.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
JNJ-7706621
CAS:443797-96-4
JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.
Formula:
C15H12F2N6O3S
Purity:
99.1% - 99.66%
Color and Shape:
Solid
Molecular weight:
394.36
Ref: TM-T6126
| 1mg | 51.00 € | ||
| 2mg | 66.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 277.00 € | ||
| 50mg | 508.00 € | ||
| 100mg | 713.00 € | ||
| 500mg | 1,448.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Palmatine chloride
CAS:10605-02-4
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and …
Formula:
C21H22ClNO4
Purity:
97.9% - 99.47%
Color and Shape:
Solid
Molecular weight:
387.857
Ref: TM-T2718
| 1g | 73.00 € | ||
| 500mg | 46.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Palmatine
CAS:3486-67-7
Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, …
Formula:
C21H22NO4
Purity:
96.28% - 99.49%
Color and Shape:
Solid
Molecular weight:
352.4
Ref: TM-T5S0802
| 1g | 89.00 € | ||
| 250mg | 59.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
XL228
CAS:898280-07-4
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM …
Formula:
C22H31N9O
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
437.54
Ref: TM-T17267
| 1mg | 55.00 € | ||
| 2mg | 77.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 569.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Tozasertib
CAS:639089-54-6
Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).
Formula:
C23H28N8OS
Purity:
99.99%
Color and Shape:
Solid
Molecular weight:
464.59
Ref: TM-T2509
| 50mg | 67.00 € | ||
| 100mg | 98.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
PHA-680632
CAS:398493-79-3
PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of …
Formula:
C28H35N7O2
Purity:
98.20%
Color and Shape:
Solid
Molecular weight:
501.62
Ref: TM-T6338
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 237.00 € | ||
| 100mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
GW779439X
CAS:551919-98-3
GW779439X is an inhibitor of CDK.
Formula:
C22H21F3N8
Purity:
97.87%
Color and Shape:
Solid
Molecular weight:
454.45
Ref: TM-T8866
| 1mg | 60.00 € | ||
| 2mg | 85.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 611.00 € | ||
| 100mg | 875.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
