Aurora Kinase
Aurora kinase inhibitors target the Aurora kinases, a family of serine/threonine kinases that play a critical role in the regulation of mitosis. These kinases are essential for proper chromosome alignment, segregation, and cytokinesis during cell division. Abnormal Aurora kinase activity can lead to uncontrolled cell proliferation and cancer. By inhibiting Aurora kinases, these compounds can induce cell cycle arrest and apoptosis in cancer cells, making them valuable tools in cancer research and therapy. At CymitQuimica, we offer a wide range of high-quality Aurora kinase inhibitors to support your research in cell cycle regulation, mitosis, and oncology.
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AMG 900
CAS:945595-80-2
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with …
Formula:
C28H21N7OS
Purity:
98.35% - 98.9%
Color and Shape:
Solid
Molecular weight:
503.58
Ref: TM-T6380
| 1mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 457.00 € | ||
| 100mg | 670.00 € | ||
| 500mg | 1,384.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CCT241736
CAS:1402709-93-6
CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant …
Formula:
C22H23Cl2N7
Purity:
96.2% - 99.88%
Color and Shape:
Solid
Molecular weight:
456.37
Ref: TM-T4428
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 482.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Barasertib-HQPA
CAS:722544-51-6
Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold …
Formula:
C26H30FN7O3
Purity:
98.43% - 99.29%
Color and Shape:
Solid
Molecular weight:
507.56
Ref: TM-T2602
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 403.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SCH-1473759 hydrochloride
CAS:1094067-13-6
SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and …
Formula:
C20H27ClN8OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
463
Ref: TM-T12864
| 2mg | 109.00 € | ||
| 5mg | 204.00 € | ||
| 10mg | 356.00 € | ||
| 1mL*10mM (DMSO) | 217.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
MK-5108
CAS:1010085-13-8
MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value …
Formula:
C22H21ClFN3O3S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
461.94
Ref: TM-T6068
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 517.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
CD532
CAS:1639009-81-6
CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, …
Formula:
C26H25F3N8O
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
522.52
Ref: TM-T50110
| 1mg | 39.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Chiauranib
CAS:1256349-48-0
Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R …
Formula:
C27H21N3O3
Purity:
96.25%
Color and Shape:
Solid
Molecular weight:
435.47
Ref: TM-T35570
| 1mg | 89.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 300.00 € | ||
| 25mg | 508.00 € | ||
| 50mg | 732.00 € | ||
| 100mg | 1,003.00 € | ||
| 1mL*10mM (DMSO) | 213.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
L 888607 Racemate
CAS:1030017-51-6
L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.
Formula:
C19H15ClFNO2S
Color and Shape:
Solid
Molecular weight:
375.84
Ref: TM-T15829
| 25mg | 1,002.00 € | ||
| 50mg | 1,320.00 € | ||
| 100mg | 1,863.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Tripolin A
CAS:1148118-92-6
Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora …
Formula:
C15H11NO3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
253.25
Ref: TM-T8537
| 25mg | 759.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Ilorasertib hydrochloride
CAS:1847485-91-9
Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora …
Formula:
C25H22ClFN6O2S
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
525
Ref: TM-T11638
| 1mg | 58.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
XU1
CAS:53439-81-9
XU1(Benzo[c][1,8]naphthyridin-6(5h)-One) is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for …
Formula:
C12H8N2O
Purity:
100% - 98.97%
Color and Shape:
Solid
Molecular weight:
196.2
Ref: TM-T29170
| 1mg | 307.00 € | ||
| 5mg | 730.00 € | ||
| 10mg | 1,016.00 € | ||
| 25mg | 1,538.00 € | ||
| 50mg | 2,079.00 € | ||
| 100mg | 2,750.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
MBM-17
CAS:2083621-90-1
MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).
Formula:
C28H28N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
480.56
Ref: TM-T11958
| 25mg | 1,545.00 € | ||
| 50mg | 2,039.00 € | ||
| 100mg | 2,619.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
MBM-17S
CAS:2083621-91-2
MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively …
Formula:
C36H40N6O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
716.74
Ref: TM-T11959
| 25mg | 1,549.00 € | ||
| 50mg | 2,039.00 € | ||
| 100mg | 2,619.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Aurora Kinases-IN-4
CAS:2877011-84-0
Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an …
Formula:
C26H28N8O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
468.55
Ref: TM-T78753
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
CCT129202
CAS:942947-93-5
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with …
Formula:
C23H25ClN8OS
Purity:
98.14%
Color and Shape:
Solid
Molecular weight:
497.02
Ref: TM-T6435
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 248.00 € | ||
| 50mg | 395.00 € | ||
| 100mg | 584.00 € | ||
| 500mg | 1,254.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
AAPK-25
CAS:2247919-28-2
AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.
Formula:
C21H13Cl2N3O2S
Purity:
97.79%
Color and Shape:
Solid
Molecular weight:
442.32
Ref: TM-T10215
| 1mg | 95.00 € | ||
| 5mg | 199.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 543.00 € | ||
| 50mg | 814.00 € | ||
| 100mg | 1,182.00 € | ||
| 1mL*10mM (DMSO) | 230.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
TC-A 2317 hydrochloride
CAS:1245907-03-2
TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 …
Formula:
C19H29ClN6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
392.93
Ref: TM-T23426
| 50mg | 3,016.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
LY3295668
CAS:1919888-06-4
LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and …
Formula:
C24H26ClF2N5O2
Purity:
99.44%
Color and Shape:
Solid
Molecular weight:
489.95
Ref: TM-T15815
| 1mg | 140.00 € | ||
| 5mg | 331.00 € | ||
| 10mg | 490.00 € | ||
| 25mg | 799.00 € | ||
| 50mg | 1,096.00 € | ||
| 100mg | 1,483.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
TY-011
CAS:1389439-77-3
TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell …
Formula:
C18H16ClN5
Color and Shape:
Liquid
Molecular weight:
337.81
Ref: TM-T89833
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Mar 2025
Aurora inhibitor 1
CAS:2227019-45-4
Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM …
Formula:
C23H25N9S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
459.57
Ref: TM-T10412
| 25mg | 2,801.00 € | ||
| 50mg | 3,708.00 € | ||
| 100mg | 5,124.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
