Aurora Kinase
Aurora kinase inhibitors target the Aurora kinases, a family of serine/threonine kinases that play a critical role in the regulation of mitosis. These kinases are essential for proper chromosome alignment, segregation, and cytokinesis during cell division. Abnormal Aurora kinase activity can lead to uncontrolled cell proliferation and cancer. By inhibiting Aurora kinases, these compounds can induce cell cycle arrest and apoptosis in cancer cells, making them valuable tools in cancer research and therapy. At CymitQuimica, we offer a wide range of high-quality Aurora kinase inhibitors to support your research in cell cycle regulation, mitosis, and oncology.
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NU6140
CAS:444723-13-1
NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).
Formula:
C23H30N6O2
Purity:
98.33%
Color and Shape:
Solid
Molecular weight:
422.52
Ref: TM-T16359
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 426.00 € | ||
| 200mg | 596.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
11α-O-Tigloyl-12β-O-acetyltenacigenin B
CAS:154022-51-2
11α-O-Tigloyl-12β-O-acetyltenacigenin B, an ester derivative isolated from Garcinia cambogia (MTC), modulates the antitumor effects of …
Formula:
C28H40O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
488.61
Ref: TM-T83459
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
TAK-901
CAS:934541-31-8
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid …
Formula:
C28H32N4O3S
Purity:
97.38% - 99.1%
Color and Shape:
Solid
Molecular weight:
504.64
Ref: TM-T2709
| 5mg | 76.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 363.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Aurora A inhibitor 3
Aurora A Inhibitor 3 (Compound 5h) effectively inhibits Aurora-A kinase, exhibiting an IC50 of 0.78 …
Purity:
98%
Ref: TM-T82931
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
SP-96
CAS:2682114-54-9
SP-96: Aurora B inhibitor, IC50=0.316 nM, selectively hinders MDA-MD-468 growth, GI50=107 nM, for triple-negative breast …
Formula:
C25H20FN7O
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
453.47
Ref: TM-T41256
| 1mg | 73.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 247.00 € | ||
| 25mg | 482.00 € | ||
| 50mg | 701.00 € | ||
| 100mg | 985.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
dAURK-4 hydrochloride
dAURK-4 hydrochloride, a derivative of Alisertib, functions as a potent and selective degrader of AURKA …
Formula:
C52H53Cl2FN8O12
Purity:
99.44%
Color and Shape:
Liquid
Molecular weight:
1071.93
Ref: TM-T74100
| 1mg | 127.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
GSK-1070916
CAS:942918-07-2
GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 …
Formula:
C30H33N7O
Purity:
98.51%
Color and Shape:
Solid
Molecular weight:
507.63
Ref: TM-T6129
| 1mg | 48.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 156.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 604.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
TAS-119
CAS:1453099-83-6
TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an …
Formula:
C23H22Cl2FN5O3
Purity:
98.69%
Color and Shape:
Solid
Molecular weight:
506.36
Ref: TM-T34787
| 1mg | 95.00 € | ||
| 5mg | 231.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,142.00 € | ||
| 100mg | 1,606.00 € | ||
| 1mL*10mM (DMSO) | 260.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
AKI603
CAS:1432515-73-5
AKI603: Aurora A kinase blocker; IC50 12.3 nM; targets BCR-ABL-T315I resistance; halts leukemia cell growth.
Formula:
C19H23N9O2
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
409.45
Ref: TM-T64338
| 1mg | 64.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | 541.00 € | ||
| 100mg | 762.00 € | ||
| 200mg | 1,025.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
AURKA against 1
Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase …
Formula:
C28H32FN9O2
Color and Shape:
Liquid
Molecular weight:
545.61
Ref: TM-T89903
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Barasertib
CAS:722543-31-9
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor …
Formula:
C26H31FN7O6P
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
587.54
Ref: TM-T14371
| 2mg | 50.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 205.00 € | ||
| 50mg | 361.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
AT9283
CAS:896466-04-9
AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, …
Formula:
C19H23N7O2
Purity:
99.87% - 99.98%
Color and Shape:
Solid
Molecular weight:
381.43
Ref: TM-T3068
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 488.00 € | ||
| 100mg | 711.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Reversine
CAS:656820-32-5
Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora …
Formula:
C21H27N7O
Purity:
98% - 99.75%
Color and Shape:
Solid
Molecular weight:
393.49
Ref: TM-T1825
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 161.00 € | ||
| 50mg | 219.00 € | ||
| 100mg | 384.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BI-847325
CAS:1207293-36-4
BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values …
Formula:
C29H28N4O2
Purity:
97.13% - 97.54%
Color and Shape:
Solid
Molecular weight:
464.56
Ref: TM-T6785
| 1mg | 49.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 506.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Aurora kinase inhibitor-2
CAS:331770-21-9
Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A …
Formula:
C23H20N4O3
Purity:
98.66%
Color and Shape:
Solid
Molecular weight:
400.43
Ref: TM-T9040
| 1mg | 64.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 205.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 543.00 € | ||
| 100mg | 803.00 € | ||
| 200mg | 1,081.00 € | ||
| 1mL*10mM (DMSO) | 162.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Alisertib
CAS:1028486-01-2
Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of …
Formula:
C27H20ClFN4O4
Purity:
100% - 99.82%
Color and Shape:
Solid
Molecular weight:
518.92
Ref: TM-T2241
| 5mg | 54.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 346.00 € | ||
| 200mg | 444.00 € | ||
| 500mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ENMD-2076
CAS:934353-76-1
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, …
Formula:
C21H25N7
Purity:
97.63% - ≥95%
Color and Shape:
Solid
Molecular weight:
375.47
Ref: TM-T2358
| 1mg | 51.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 156.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 638.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PF 477736
CAS:952021-60-2
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) …
Formula:
C22H25N7O2
Purity:
98% - 98.34%
Color and Shape:
Solid
Molecular weight:
419.48
Ref: TM-T6028
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Phthalazinone pyrazole
CAS:880487-62-7
Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.
Formula:
C18H15N5O
Purity:
97.03%
Color and Shape:
Solid
Molecular weight:
317.34
Ref: TM-T21981
| 1mg | 62.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 762.00 € | ||
| 200mg | 1,025.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TCS7010
CAS:1158838-45-9
TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A …
Formula:
C31H31ClFN7O2
Purity:
98.49% - 99.62%
Color and Shape:
Solid
Molecular weight:
588.07
Ref: TM-T6767
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 323.00 € | ||
| 500mg | 766.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
