Bombesin Receptor
Bombesin receptors are a group of GPCRs that are activated by bombesin-like peptides, which are involved in regulating gastrointestinal function, energy balance, and cell proliferation. These receptors are of particular interest in cancer research, as they are often overexpressed in certain types of tumors. Bombesin receptor antagonists are studied for their potential as cancer therapeutics. At CymitQuimica, we provide a selection of high-quality bombesin receptor modulators to support your research in oncology, gastrointestinal physiology, and receptor signaling.
Found 37 products for "Bombesin Receptor".
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PD176252
CAS:PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.Formula:C32H36N6O5Purity:99.00%Color and Shape:SolidMolecular weight:584.67[D-Phe12]-Bombesin acetate
[D-Phe12]-Bombesin acetate inhibits bombesin-stimulated secretion.Formula:C76H116N22O20SPurity:99.81%Color and Shape:SolidMolecular weight:1689.94Litorin acetate(55749-97-8 Free base)
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist.Formula:C53H72N14O13SPurity:98.61%Color and Shape:SolidMolecular weight:1145.29ML-18
CAS:ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.Formula:C32H35N5O5Purity:98.62% - >99.99%Color and Shape:White SolidMolecular weight:569.65Ref: TM-T4540
1mg34.00€5mg60.00€1mL*10mM (DMSO)75.00€10mg96.00€25mg170.00€50mg264.00€100mg425.00€200mg587.00€Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Formula:C45H44O11Purity:97.09% - 97.99%Color and Shape:Orange SolidMolecular weight:760.82BA 1 acetate(183241-31-8 free base)
BA 1 acetate: bombesin agonist, IC50s: 0.26/1.55/2.52 nM (BB1/BB2/BB3), boosts glucose transport, promotes lung cancer cell growth in vitro.Formula:C59H80N14O13Purity:99.98%Color and Shape:White SolidMolecular weight:1193.35[D-Phe12,Leu14]-Bombesin acetate
[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.Formula:C77H118N22O20Purity:96.99%Color and Shape:White SolidMolecular weight:1671.9kuwanon G
CAS:Kuwanon G (Moracenin B) may be used to treat the type II diabetes mellitus as a dual inhibitor of PTP1B and α-glucosidase and as an insulin sensitiser.Formula:C40H36O11Purity:98% - 99.57%Color and Shape:Yellow SolidMolecular weight:692.71Ref: TM-T3S1612
1mg63.00€5mg138.00€1mL*10mM (DMSO)178.00€10mg198.00€25mg321.00€50mg465.00€100mg627.00€200mg845.00€MK-5046
CAS:MK-5046 is a novel BRS-3 agonist, binding to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).Formula:C20H18F6N4OPurity:98.56%Color and Shape:SolidMolecular weight:444.37DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Formula:C23H24N2O7Purity:98%Color and Shape:SolidMolecular weight:440.45Bag-1
CAS:Bag-1 is a BRS-3 agonist (EC₅₀=2.5 nM).Formula:C22H27N3Purity:99.73%Color and Shape:Yellow SolidMolecular weight:333.47PD 165929
CAS:PD 165929 is a selective antagonist of Bombesin BB1.Formula:C37H47N5O2Purity:98%Color and Shape:SolidMolecular weight:593.8PD 168368
CAS:PD 168368 is a mixed neuromodulin B receptor (NMB-R) antagonist and potent FPR1/FPR2/FPR3 agonist that inhibits the gastrin-releasing peptide receptor.Formula:C31H34N6O4Purity:98.11% - 99.87%Color and Shape:White SolidMolecular weight:554.64Ref: TM-T8691
1mg84.00€5mg167.00€1mL*10mM (DMSO)197.00€10mg245.00€25mg492.00€50mg737.00€100mg1,054.00€GRPR antagonist-1
GRPR antagonist-1 targets GRPR, kills specific cancer cells (e.g., PC3, Pan02, HGC-27), and promotes apoptosis by modulating Bcl-2 and Bax.Formula:C29H33F3N4O4Color and Shape:SolidMolecular weight:558.59PD 168368 derivative-1
CAS:PD 168368 derivative-1 (Compound 16) is a derivative of PD 168368, exhibiting Ki values of 0.46 nM and 3.7 nM for bombesin receptor subtypes (BB₁ and BB₂) respectively. This compound can be utilized in the study of various diseases such as cancer, depression, and eating disorders.Formula:C33H37N5O5Molecular weight:583.69GRPR antagonist-3
CAS:GRPR antagonist-3 (compound (S)-1m) is a potent GRPR antagonist with an IC50 of 121 nM. It is stable in rat plasma and exhibits strong resistance to oxidative metabolism by microsomes in vitro. Additionally, GRPR antagonist-3 can be radiolabeled with fluorine-18 for use in PET imaging.Formula:C33H37FN6O5Molecular weight:616.69GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Formula:C28H32F3N5O4Color and Shape:SolidMolecular weight:559.58
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