Histamine Receptor
Histamine receptors are GPCRs that mediate the effects of histamine, a biogenic amine involved in immune responses, gastric acid secretion, and neurotransmission. There are four subtypes of histamine receptors (H1, H2, H3, and H4), each playing distinct roles in allergic reactions, gastric function, and central nervous system activity. Histamine receptor antagonists are widely used in the treatment of allergies, peptic ulcers, and motion sickness. At CymitQuimica, we provide a comprehensive selection of high-quality histamine receptor modulators to support your research in immunology, gastroenterology, and neuropharmacology.
Found 358 products of "Histamine Receptor"
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FR-A 19
CAS:<p>FR-A 19: Histamine H2 agonist, nanomolar inhibition of basophil histamine release; potent anti-allergic.</p>Formula:C25H34Cl3F2N5Color and Shape:SolidMolecular weight:548.93VUF 8328
CAS:<p>VUF 8328 is an agonist of histamine H(3) receptor.</p>Formula:C7H12N4SPurity:98%Color and Shape:SolidMolecular weight:184.26Adriforant
CAS:<p>Adriforant (PF-3893787,ZPL-3893797) is a competitive histamine receptor 4 h4 antagonist that antagonizes histamine-induced phosphorylation of ERK, inflammation.</p>Formula:C13H22N6Purity:99.84%Color and Shape:SolidMolecular weight:262.35FRG8701
CAS:<p>FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.</p>Formula:C22H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:418.55ReN-1869 hydrochloride
CAS:<p>ReN 1869 hydrochloride is a novel, selective antagonist of histamine H1 receptor.</p>Formula:C24H28ClNO2Purity:98%Color and Shape:SolidMolecular weight:397.94H4R antagonist 1
CAS:<p>H4R antagonist 1: selective histamine H4R inhibitor, IC50 27 nM, no affinity for H1R, H2R, H3R.</p>Formula:C11H11BrN8Color and Shape:SolidMolecular weight:335.16(±)-Tazifylline
CAS:<p>(±)-Tazifylline is a selective and long-acting antagonist of histamine H1 receptor.</p>Formula:C23H32N6O3SPurity:99.54%Color and Shape:SolidMolecular weight:472.6Noberastine
CAS:<p>Noberastine (R 64947) is a novel histamine H1 antagonist with potent and specific peripheral antihistamine activity.</p>Formula:C17H21N5OPurity:99.72% - >99.99%Color and Shape:SolidMolecular weight:311.38KSK68
CAS:<p>KSK68 is a sigma-1 and histamine H3 receptor antagonist with analgesic activity, inhibits H3 receptors and can be used to study pain.</p>Formula:C23H28N2O2Purity:99.11%Color and Shape:SolidMolecular weight:364.48Immethridine dihydrobromide
CAS:<p>Immethridine dihydrobromide is a histamine H3 receptor agonist.</p>Formula:C9H11Br2N3Purity:97.61% - 98.14%Color and Shape:SolidMolecular weight:321.01D18024
CAS:<p>D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.</p>Formula:C29H31ClFN3OPurity:99.86%Color and Shape:SolidMolecular weight:492.03Impromidine hydrochloride
CAS:<p>Impromidine hydrochloride is a very potent and specific histamine H2 receptor agonist for conducting cardiovascular studies.</p>Formula:C14H26Cl3N7SPurity:99.82%Color and Shape:SolidMolecular weight:430.83Enerisant hydrochloride
CAS:<p>Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteins</p>Formula:C22H31ClN4O3Purity:99.95%Color and Shape:SolidMolecular weight:434.96Linetastine
CAS:<p>Linetastine (TMK-688) inhibits 5-LOX, blocks leukotrienes, counters histamine; researched for asthma, atherosclerosis, ulcers.</p>Formula:C35H40N2O6Purity:99.76%Color and Shape:SolidMolecular weight:584.7Pitolisant
CAS:<p>Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.</p>Formula:C17H26ClNOPurity:99.84%Color and Shape:SolidMolecular weight:295.85KSK94
CAS:<p>KSK94 is an H3 receptor antagonist that inhibits sigma-2 receptors , with a Ki value of 75.2 nM, and can be used to study injurious pain.</p>Formula:C25H26N4OPurity:99.60%Color and Shape:SolidMolecular weight:398.5Irdabisant
CAS:<p>Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.</p>Formula:C18H23N3O2Purity:99.96%Color and Shape:SolidMolecular weight:313.39Efletirizine
CAS:<p>Efletirizine (UCB-28754), a histamine blocker and 5-LO inhibitor, aids in topical allergy treatment.</p>Formula:C21H24F2N2O3Purity:99.39%Color and Shape:SolidMolecular weight:390.42Antihistamine-1
CAS:<p>Antihistamine-1 是能够渗透血脑屏障的 H1-抗组胺药 (Ki=6.9 nM), 它也是 CYP2D6 和 hERG 通道的抑制剂，其 IC50 值分别为 5.4 和 0.8 μM。</p>Formula:C23H24FN5Purity:99.69%Color and Shape:SolidMolecular weight:389.47NP10679
CAS:<p>NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.</p>Formula:C23H26F3N3O3Purity:99.43%Color and Shape:SolidMolecular weight:449.47Proxyfan
CAS:<p>Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.</p>Formula:C13H16N2OPurity:99.68%Color and Shape:SolidMolecular weight:216.28ReN-1869
CAS:<p>ReN-1869 is a novel selective histamine H(1) receptor antagonist with anti-neurogenic pain and anti-inflammatory activity for the study of neurological diseases</p>Formula:C24H27NO2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:361.48DF-1111301
CAS:<p>DF-1111301 is a novel anti-allergic compound with anti-histamine H1 and anti-PAF activity.</p>Formula:C15H25Cl2N3OPurity:99.17%Color and Shape:SolidMolecular weight:334.29Eclazolast
CAS:<p>Eclazolast (RHC 2871), a lipophilic anti-allergic, inhibits mast cell mediator release by affecting Fc(epsilon)RI-related processes, dose-dependently.</p>Formula:C12H12ClNO4Purity:98.36% - 98.58%Color and Shape:SolidMolecular weight:269.68KP136
CAS:<p>KP136 is an orally effective antiallergic compound (IC50: 76.1 μg/mL for histamine release and 63 ug/mL for degranulation).</p>Formula:C16H18N4O3Purity:98.3% - 98.61%Color and Shape:SolidMolecular weight:314.34Bavisant
CAS:<p>Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist.</p>Formula:C19H27N3O2Purity:99.21% - 99.65%Color and Shape:SolidMolecular weight:329.44Abt-288
CAS:<p>ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.</p>Formula:C23H24N4OPurity:98.17% - 98.49%Color and Shape:SolidMolecular weight:372.46Clemastine
CAS:<p>Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects.</p>Formula:C21H26ClNOPurity:99.21%Color and Shape:SolidMolecular weight:343.89JZP-361
CAS:<p>JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.</p>Formula:C22H20ClN5OPurity:99.82%Color and Shape:SolidMolecular weight:405.88JNJ-28583867
CAS:<p>JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.</p>Formula:C24H32N2O2SColor and Shape:SolidMolecular weight:412.59Cipralisant maleate
CAS:<p>Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.</p>Formula:C18H24N2O4Color and Shape:SolidMolecular weight:332.39CI-949
CAS:<p>CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).</p>Formula:C20H20N6O3Purity:98%Color and Shape:SolidMolecular weight:392.41Ebrotidine
CAS:<p>Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.</p>Formula:C14H17BrN6O2S3Purity:97.519%Color and Shape:SolidMolecular weight:477.42GSK-1004723
CAS:<p>GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.</p>Formula:C39H49ClN4O2Color and Shape:SolidMolecular weight:641.28Quinotolast sodium
CAS:<p>Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.</p>Formula:C17H12N6NaO3Purity:98%Color and Shape:SolidMolecular weight:371.312UCB-35440
CAS:<p>UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.</p>Formula:C31H34ClN5O4Color and Shape:SolidMolecular weight:576.09Minocromil
CAS:<p>Minocromil is a new agent of Anti-asthmatic.</p>Formula:C18H16N2O6Purity:98%Color and Shape:SolidMolecular weight:356.33A-349821
CAS:<p>A-349821 is an H3 receptor agonist radioligand.</p>Formula:C28H35F3N2O5Color and Shape:SolidMolecular weight:536.59GT-2331
CAS:<p>GT-2331 is a histamine H3 receptor antagonist.</p>Formula:C14H20N2Color and Shape:SolidMolecular weight:216.32Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Formula:C26H29FN2O2Color and Shape:SolidMolecular weight:420.52H3 receptor antagonist 1
CAS:<p>H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.</p>Formula:C20H28F2N2OPurity:98%Color and Shape:SolidMolecular weight:350.45H4R antagonist 2
CAS:<p>H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoid</p>Formula:C13H17N5OPurity:98%Color and Shape:SolidMolecular weight:259.31Cipralisant
CAS:<p>Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.</p>Formula:C14H20N2Purity:98%Color and Shape:SolidMolecular weight:216.32Levocabastine hydrochloride
CAS:<p>Levocabastine HCl is an agent with antihistaminic activity.</p>Formula:C26H30ClFN2O2Color and Shape:SolidMolecular weight:456.98ST-1006
CAS:<p>ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.</p>Formula:C16H20Cl2N6Purity:98.87% - 99.96%Color and Shape:SolidMolecular weight:367.28Enerisant
CAS:<p>Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.</p>Formula:C22H30N4O3Purity:99.7%Color and Shape:SoildMolecular weight:398.50Tixanox sodium
CAS:<p>Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.</p>Formula:C15H9NaO5SColor and Shape:SolidMolecular weight:324.28CI-624
CAS:<p>CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.</p>Formula:C8H8N2SColor and Shape:SolidMolecular weight:164.228H3R antagonist 5
CAS:<p>H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.</p>Formula:C23H32N2O4Color and Shape:SolidMolecular weight:400.511Arpromidine
CAS:<p>Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.</p>Formula:C21H25FN6Color and Shape:SolidMolecular weight:380.462H1R ligand-1
CAS:<p>H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.</p>Formula:C19H23NOColor and Shape:SolidMolecular weight:281.392Nedocromil sodium
CAS:<p>Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.</p>Formula:C19H17NNaO7Purity:98%Color and Shape:SolidMolecular weight:394.335UR-AK49
CAS:<p>UR-AK49 (compound 11) is an agonist for the human histamine H1 and H2 receptors. It exhibits an EC50 of 23 nM in the GTPase assay involving hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 is applicable in neurologically related research.</p>Formula:C16H27N5OColor and Shape:SolidMolecular weight:305.42FR-145715
CAS:<p>FR-145715 is a histamine H2 receptor antagonist characterized by its specific anti-Helicobacter pylori activity. This compound is utilized in the study of gastric lesions.</p>Formula:C16H21N5O2SColor and Shape:SolidMolecular weight:347.44Histamine H3 antagonist-1
CAS:<p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>Formula:C24H28F3N3O2Color and Shape:SolidMolecular weight:447.49H3R antagonist 1
CAS:<p>H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).</p>Formula:C19H23N3O3Color and Shape:SolidMolecular weight:341.4(R)-(-)-α-Methylhistamine dihydrochloride
CAS:<p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>Formula:C6H13Cl2N3Color and Shape:SolidMolecular weight:198.09Imetit dihydrobromide
CAS:<p>Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).</p>Formula:C6H12Br2N4SPurity:98%Color and Shape:SolidMolecular weight:332.06
