Histamine Receptor
Histamine receptors are GPCRs that mediate the effects of histamine, a biogenic amine involved in immune responses, gastric acid secretion, and neurotransmission. There are four subtypes of histamine receptors (H1, H2, H3, and H4), each playing distinct roles in allergic reactions, gastric function, and central nervous system activity. Histamine receptor antagonists are widely used in the treatment of allergies, peptic ulcers, and motion sickness. At CymitQuimica, we provide a comprehensive selection of high-quality histamine receptor modulators to support your research in immunology, gastroenterology, and neuropharmacology.
Found 385 products of "Histamine Receptor"
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Eclazolast
CAS:Eclazolast (RHC 2871), a lipophilic anti-allergic, inhibits mast cell mediator release by affecting Fc(epsilon)RI-related processes, dose-dependently.Formula:C12H12ClNO4Purity:98.29% - 98.61%Color and Shape:SolidMolecular weight:269.68Ref: TM-T25360
1mg112.00€1mL*10mM (DMSO)249.00€5mg261.00€10mg396.00€25mg655.00€50mg888.00€100mg1,251.00€500mg2,493.00€Irdabisant
CAS:Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.Formula:C18H23N3O2Purity:99.96%Color and Shape:SolidMolecular weight:313.39UCB-35440
CAS:UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.Formula:C31H34ClN5O4Color and Shape:SolidMolecular weight:576.09Meclizine N-oxide
CAS:Meclizine N-oxide, a metabolite of the histamine H1 receptor antagonist meclizine (1), also acts as a degradation product and potential impurity in commercial meclizine preparations (2).Formula:C25H27ClN2OColor and Shape:SolidMolecular weight:407Levocabastine hydrochloride
CAS:Levocabastine HCl is an agent with antihistaminic activity.Formula:C26H30ClFN2O2Color and Shape:SolidMolecular weight:456.98Quinotolast sodium
CAS:Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.Formula:C17H12N6NaO3Purity:98%Color and Shape:SolidMolecular weight:371.312A-349821
CAS:A-349821 is an H3 receptor agonist radioligand.Formula:C28H35F3N2O5Color and Shape:SolidMolecular weight:536.59CI-949
CAS:CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).Formula:C20H20N6O3Purity:98%Color and Shape:SolidMolecular weight:392.41Ebrotidine
CAS:Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.Formula:C14H17BrN6O2S3Purity:97.519%Color and Shape:SolidMolecular weight:477.42Minocromil
CAS:Minocromil is a new agent of Anti-asthmatic.Formula:C18H16N2O6Purity:98%Color and Shape:SolidMolecular weight:356.33GT-2331
CAS:GT-2331 is a histamine H3 receptor antagonist.Formula:C14H20N2Color and Shape:SolidMolecular weight:216.32APD-916
CAS:APD-916, an H3 receptor antagonist, exhibits favorable pharmacokinetic properties. Oral administration of APD-916 has been demonstrated to enhance wakefulness in various animal models.Formula:C23H31NO3SColor and Shape:SolidMolecular weight:401.56Embramine hydrochloride
CAS:Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].Formula:C18H23BrClNOColor and Shape:SolidMolecular weight:384.74JNJ-28583867
CAS:JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.Formula:C24H32N2O2SColor and Shape:SolidMolecular weight:412.59GSK-1004723
CAS:GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.Formula:C39H49ClN4O2Color and Shape:SolidMolecular weight:641.28Cipralisant
CAS:Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.Formula:C14H20N2Purity:98%Color and Shape:SolidMolecular weight:216.32Hydroxydione
CAS:Hydroxydione, a neuroactive steroid with general anesthetic properties, is utilized in anesthesia-related research [1] [2].Formula:C21H32O3Color and Shape:SolidMolecular weight:332.48Cipralisant maleate
CAS:Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.Formula:C18H24N2O4Color and Shape:SolidMolecular weight:332.39H3 receptor antagonist 1
CAS:H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.Formula:C20H28F2N2OPurity:98%Color and Shape:SolidMolecular weight:350.45Levocabastine
CAS:Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.Formula:C26H29FN2O2Color and Shape:SolidMolecular weight:420.52H4R antagonist 2
CAS:H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoidFormula:C13H17N5OPurity:98%Color and Shape:SolidMolecular weight:259.31ST-1006
CAS:ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.Formula:C16H20Cl2N6Purity:99.96% - 99.98%Color and Shape:SolidMolecular weight:367.28Ref: TM-T34709
1mg86.00€1mL*10mM (DMSO)187.00€5mg188.00€10mg299.00€25mg487.00€50mg600.00€100mg743.00€200mg990.00€Enerisant
CAS:Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.Formula:C22H30N4O3Purity:99.7%Color and Shape:SoildMolecular weight:398.50Ref: TM-T67828
1mg49.00€2mg67.00€5mg102.00€1mL*10mM (DMSO)111.00€10mg166.00€25mg339.00€50mg439.00€100mg610.00€200mg827.00€H3R antagonist 1
CAS:H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).Formula:C19H23N3O3Color and Shape:SolidMolecular weight:341.4Tixanox sodium
CAS:Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.Formula:C15H9NaO5SColor and Shape:SolidMolecular weight:324.28H3R antagonist 5
CAS:H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.Formula:C23H32N2O4Color and Shape:SolidMolecular weight:400.511CI-624
CAS:CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.Formula:C8H8N2SColor and Shape:SolidMolecular weight:164.228H1R ligand-1
CAS:H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.Formula:C19H23NOColor and Shape:SolidMolecular weight:281.392Sitamaquine hydrochloride
CAS:Sitamaquine hydrochloride (WR 6026) is an orally active 8-aminoquinoline analog with antileishmanial activity. This compound inhibits mitochondrial complex II (succinate dehydrogenase) and is characterized by its lipophilic weak base properties. It rapidly accumulates in the acidic compartments of Leishmania parasites, predominantly localizing within the acidocalcisomes.Formula:C21H35Cl2N3OColor and Shape:SolidMolecular weight:416.43Arpromidine
CAS:Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.Formula:C21H25FN6Color and Shape:SolidMolecular weight:380.462Nedocromil sodium
CAS:Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.Formula:C19H17NNaO7Purity:98%Color and Shape:SolidMolecular weight:394.335Histamine H3 antagonist-1
CAS:Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].
Formula:C24H28F3N3O2Color and Shape:SolidMolecular weight:447.49ONO-8809
CAS:ONO-8809: Thromboxane A2 antagonist, reduces airway hyperresponse, macrophage accumulation, and MMP-9 in SHRSP brains.Formula:C30H46BrNO4SPurity:98%Color and Shape:SolidMolecular weight:596.66(R)-(-)-α-Methylhistamine dihydrochloride
CAS:R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.Formula:C6H13Cl2N3Color and Shape:SolidMolecular weight:198.09Imetit dihydrobromide
CAS:Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Formula:C6H12Br2N4SPurity:98%Color and Shape:SolidMolecular weight:332.06
