Glucagon Receptor
Glucagon receptors are GPCRs that mediate the effects of glucagon, a hormone involved in regulating glucose homeostasis by promoting glycogen breakdown and glucose release from the liver. These receptors are critical in the management of blood sugar levels and are of particular interest in the study of diabetes and metabolic disorders. Glucagon receptor antagonists are being explored as potential treatments for hyperglycemia in type 2 diabetes. At CymitQuimica, we offer a variety of high-quality glucagon receptor modulators to support your research in endocrinology, diabetes, and metabolic regulation.
Found 191 products of "Glucagon Receptor"
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Glucagon receptor antagonists-5
CAS:Oral indazole-based glucagon antagonist, Ki: 32 nM, may treat type 2 diabetes.Formula:C30H29ClF3N3O3Purity:98%Color and Shape:SolidMolecular weight:572.02Glucagon receptor antagonists-2
CAS:Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist.Formula:C22H30FNO2Purity:98%Color and Shape:SolidMolecular weight:359.48BAY-27-9955
CAS:BAY-27-9955 is a glucagon receptor antagonist.Formula:C23H31FOColor and Shape:SolidMolecular weight:342.49(S)-V-0219
(S)-V-0219: oral, GLP-1R PAM, boosts calcium in hGLP-1R HEK cells, lowers glucose, curbs hunger in mice.Formula:C20H25F3N4O2Color and Shape:SolidMolecular weight:410.43MS012
CAS:MS012 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase (Kd = 46 ± 15 nM).Formula:C22H35N5O2Color and Shape:SolidMolecular weight:401.55(R)-V-0219
(R)-V-0219: GLP-1R PAM, orally active, triggers Ca++ flux in HEK-hGLP-1R cells.Formula:C20H25F3N4O2Color and Shape:SolidMolecular weight:410.43GLP-1R agonist 1
CAS:GLP-1R agonist 1, an imidazole derivative and potent GLP-1R activator, may aid diabetes research.Formula:C32H29ClFN3O5Color and Shape:SolidMolecular weight:590.04PF-06412154 HCl
CAS:PF-06412154 HCl is a glucagon receptor antagonist.Formula:C24H28ClN3O3Color and Shape:SolidMolecular weight:441.96Efpeglenatide
CAS:Efpeglenatide is a long-acting GLP-1 receptor agonist that improves insulin sensitivity, lowers blood glucose, delays weight gain, and supports metabolic disease research.Purity:100% - 100%Color and Shape:SolidNNC 92-1687
CAS:NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.Formula:C15H12N2O3SPurity:98.70% - 99.96%Color and Shape:SolidMolecular weight:300.33L-168049
CAS:L-168049: Human glucagon receptor antagonist, IC50 - 3.7 nM human, 63 nM murine, 60 nM canine.Formula:C24H20BrClN2OPurity:>99.99%Color and Shape:SolidMolecular weight:467.79Ref: TM-T22893
1mg50.00€5mg105.00€10mg170.00€25mg358.00€50mg530.00€100mg758.00€500mg1,558.00€1mL*10mM (DMSO)116.00€GLP-1R agonist 3
CAS:GLP-1R agonist 3 is a GLP-1R agonist, an imidazole derivative.GLP-1R agonist 3 can be used to study diabetes and obesity.Formula:C31H28FN5O4Purity:97.19%Color and Shape:SolidMolecular weight:553.58Glucagon receptor antagonists-3
CAS:Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.Formula:C22H30FNO2Purity:98%Color and Shape:SolidMolecular weight:359.48GLP-1 receptor agonist 3
CAS:GLP-1 receptor agonist 3 is a GLP-1 receptor agonist,Example 4A-1, has EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively.Formula:C31H30FN5O4Purity:98%Color and Shape:SolidMolecular weight:555.6MK 0893
CAS:MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist competitive, reversible cAMP activity, which attenuates blood glucose elevation.Formula:C32H27Cl2N3O4Purity:98.79%Color and Shape:SolidMolecular weight:588.48GLP-1R agonist 17
CAS:GLP-1R agonist 17 excels in stimulating GLP-1 receptors, useful for cardiovascular metabolic disease research.Formula:C28H26ClFN4O4SColor and Shape:SolidMolecular weight:569.05LGD-6972 sodium
CAS:LGD-6972 sodium is a glucagon receptor antagonist.Formula:C43H46N2NaO5SPurity:98%Color and Shape:SolidMolecular weight:725.9GLP-1R agonist 9
CAS:GLP-1R agonist 9 acts as a GLP-1R agonist, demonstrating efficacy with EC50 values of 1.1 nM and 11 nM against CHO GLP-1R Clone H6 and Clone C6, respectively.Formula:C32H30ClF2N3O5Color and Shape:SolidMolecular weight:610.05GLP-1R agonist 10
CAS:GLP-1R agonist 10 is a GLP-1 agonist (EC50: 0.051 nM).Formula:C29H29ClFN5O4Color and Shape:SolidMolecular weight:566.02MK3577
CAS:MK3577 is a glucagon receptor antagonist.Formula:C30H30ClFN2O3Color and Shape:SolidMolecular weight:521.02GLP-1R agonist 12
CAS:GLP-1R agonist 12 (Compound 123) 是一种 GLP-1R 激动剂，能够用于研究糖尿病。Formula:C34H36N6O4Color and Shape:SolidMolecular weight:592.69Antitumor agent-101
CAS:Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM forFormula:C26H38N6O3Purity:98%Color and Shape:SolidMolecular weight:482.62Lotiglipron
CAS:Lotiglipron (PF-07081532) is a GLP-1R agonist that lowers blood glucose and may be used in the study of type 2 diabetes mellitus (T2DM) and excess obesity.
Formula:C31H31ClN4O5Purity:98.3%Color and Shape:SolidMolecular weight:575.05Adomeglivant
CAS:Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.Formula:C32H36F3NO4Purity:99.91%Color and Shape:SolidMolecular weight:555.63LGD-6972
CAS:LGD-6972 is an antagonist of glucagon receptor.
Formula:C43H46N2O5SPurity:98.8% - 99.62%Color and Shape:SolidMolecular weight:702.9GLP-1 receptor agonist 16
CAS:GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.Formula:C33H31ClFN3O4Color and Shape:SolidMolecular weight:588.068DA-302168S
CAS:DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.Formula:C33H24ClF2N3O5Color and Shape:SolidMolecular weight:616.011GLP-1 receptor agonist 12
CAS:Compound 20A, known as GLP-1 receptor agonist 12, acts as an agonist of the GLP receptor. It is utilized in researching diseases like diabetes [1].Formula:C31H31FN6O4Molecular weight:570.61GLP-1R agonist 32
CAS:GLP-1R agonist 32 (Compound 111) is an orally active and potent GLP-1R agonist with an EC50 value of 0.017 nM. It stimulates the production of cyclic adenosine monophosphate (cAMP) by activating GLP-1R, which enhances insulin secretion, suppresses glucagon release, and delays gastric emptying to regulate blood glucose levels. GLP-1R agonist 32 shows potential for research in type 2 diabetes, obesity, and related metabolic disorders.Formula:C32H31ClFN3O5Color and Shape:SolidMolecular weight:592.06GLP-1 receptor agonist 11
CAS:GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].Formula:C31H31ClFN3O4Color and Shape:SolidMolecular weight:564.05GLP-1 receptor agonist 15
CAS:GLP-1 receptor agonist 15 (Example 4) is a GLP receptor agonist with an EC50 of 0.74 nM. It exhibits an IC50 of 10.1 μM against the hERG potassium ion channel. This compound is applicable for research in the diabetes field.Formula:C32H31ClFN3O5Color and Shape:SolidMolecular weight:592.057GLP-1R agonist 33
CAS:GLP-1R agonist 33 (Compound 224) is a GLP-1 receptor agonist with potential applications in research related to diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).Formula:C30H27FN6O4Color and Shape:SolidMolecular weight:554.57PF-06372222
CAS:PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.Formula:C26H28F3N5O3Purity:98%Color and Shape:SolidMolecular weight:515.53GLP-1R modulator-1
CAS:GLP-1R modulator-1 (Compound 384) is a potent and orally active selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). It activates G protein-coupled signaling, leading to increased intracellular cAMP levels, enhanced insulin secretion, delayed gastric emptying, and reduced appetite. GLP-1R modulator-1 holds potential for research in type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).Formula:C41H38ClFN6O4Color and Shape:SolidMolecular weight:733.23LXT34
CAS:LXT34 (Example 2) is a GPR120 agonist with anti-inflammatory properties. This compound enhances GLP-1 formation in the gastrointestinal tract and improves insulin resistance in macrophages and pancreatic cells. LXT34 is applicable in studies related to inflammatory conditions, such as type 2 diabetes, obesity, and non-alcoholic fatty liver disease.Formula:C18H21NO3SColor and Shape:SolidMolecular weight:331.43GLP-1 receptor agonist 10
CAS:GLP-1 Receptor Agonist 10 (Compound 42), an agonist of the GLP receptor, reduces glucose excursions and inhibits food intake in mice. It is useful for research into type 2 diabetes (T2DM) and obesity [1].Formula:C30H28F4N6O5Color and Shape:SolidMolecular weight:628.57SCH-900822
CAS:SCH-900822 is a potent and selective glucagon receptor antagonist.Formula:C34H43Cl2N7O2Color and Shape:SolidMolecular weight:652.66GLP-1R agonist 8
CAS:GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).Formula:C33H32N4O5Color and Shape:SolidMolecular weight:564.63DS79932728
CAS:DS79932728 is an orally active inhibitor of G9a and GLP, with IC50 values of 12.6 nM and 75.7 nM, respectively. It induces the production of γ-globin, thereby increasing fetal hemoglobin (HbF) levels. In cynomolgus monkey models, DS79932728 enhances the proportion of F-reticulocytes (F-rets) and shows good oral absorption characteristics.Formula:C19H25N3OColor and Shape:SolidMolecular weight:311.421LSN3318839
CAS:LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can
Formula:C26H23Cl2N3O2Purity:99.21%Color and Shape:SolidMolecular weight:480.39Anti-GLP1R Antibody
Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.
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