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Glucagon Receptor

Glucagon Receptor

Glucagon receptors are GPCRs that mediate the effects of glucagon, a hormone involved in regulating glucose homeostasis by promoting glycogen breakdown and glucose release from the liver. These receptors are critical in the management of blood sugar levels and are of particular interest in the study of diabetes and metabolic disorders. Glucagon receptor antagonists are being explored as potential treatments for hyperglycemia in type 2 diabetes. At CymitQuimica, we offer a variety of high-quality glucagon receptor modulators to support your research in endocrinology, diabetes, and metabolic regulation.

Found 164 products of "Glucagon Receptor"

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  • TT-OAD2

    CAS:
    <p>TT-OAD2 is a non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (EC50: 5 nM), with the potential for diabetes treatment.</p>
    Formula:C50H49Cl4N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:929.75
  • GLP-2(1-33)(human)

    CAS:
    <p>GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.</p>
    Formula:C165H254N44O55S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3766.19
  • HAEGTFT

    CAS:
    <p>HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide.</p>
    Formula:C33H47N9O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:761.78
  • GLP-1(7-36), amide acetate

    CAS:
    <p>GLP-1(7-36), amide acetate is a derivative of GLP-1 peptide , activate the GLP-1 receptor, promote insulin secretion,Type 2 diabetes mellitus and obesity.</p>
    Formula:C151H230N40O47
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:3357.68
  • Apraglutide

    CAS:
    <p>Apraglutide (FE 203799 is a synthetic 33-amino acid peptide and long-acting glp-2 analogue.</p>
    Formula:C172H263N43O52
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3765.25
  • Dulaglutide

    CAS:
    <p>Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).</p>
    Color and Shape:Solid
  • Taspoglutide

    CAS:
    <p>Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes</p>
    Formula:C152H232N40O45
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3339.763
  • LSN3160440

    CAS:
    <p>LSN3160440 is a GLP-1R allosteric modulator and PPI stabilizer aiding inactive GLP-1 attachment.</p>
    Formula:C27H27Cl2N3O
    Color and Shape:Solid
    Molecular weight:480.43
  • Des His1, Glu8 Exendin-4


    <p>Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP1R) antagonist that regulates blood glucose and is used in the study of diabetes and obesity.</p>
    Formula:C179H277N47O59S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:4063.46
  • Secretin, porcine

    CAS:
    <p>Porcine secretin: 27-amino acid peptide for diagnosing pancreatic dysfunction and gastrinoma, stimulates bicarbonate fluid.</p>
    Formula:C130H220N44O41·xC2H4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A
  • TT-OAD2 free base

    CAS:
    <p>TT-OAD2 free base, a non-peptide GLP-1 receptor agonist, can treat diabetes; has an EC50 of 5 nM.</p>
    Formula:C50H47Cl2N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:856.83
  • {Val1}-Exendin-3/4


    <p>{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide.</p>
    Formula:NA
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3241.7
  • GLP-1R agonist 14

    CAS:
    <p>GLP-1R agonist 14, also known as Compound 14, is a potent agonist of the GLP-1 receptor, demonstrating an EC50 range of 0-20 nM against human GLP-1 [1].</p>
    Formula:C45H42F2N10O5
    Color and Shape:Solid
    Molecular weight:840.88
  • GIP/GLP-1 dual receptor agonist-1

    CAS:
    <p>Compound 4: GIP/GLP-1 agonist for metabolic/fatty liver disease research.</p>
    Color and Shape:Solid
  • HAEGTFTSDVS acetate


    <p>HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells.</p>
    Formula:C50H75N13O22
    Purity:97.47%
    Color and Shape:Solid
    Molecular weight:1210.2
  • GLP-1R agonist 29


    <p>GLP-1R agonist 29 (Compound 20) is a GLP-1R agonist that induces hGLP-1R-mediated cAMP stimulation with an EC50 of 0.018 nM. It exhibits favorable pharmacokinetic properties and shows good in vivo exposure, with an AUC0-∞,sc of 77688 ng·h/mL.</p>
    Color and Shape:Odour Solid
  • Exendin-3/4 (59-86)


    <p>Exendin-3/4 (59-86) is a Exendin-4 peptide derivative.</p>
    Formula:NA
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3055.49
  • GLP-1(7-37)

    CAS:
    <p>GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon processing in intestinal endocrine L cells.</p>
    Formula:C151H228N40O47
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3355.67
  • Mazdutide acetate(2259884-03-0 free base)


    <p>Mazdutide acetate is a potent (GLP-1R and GCGR agonist that stimulates insulin secretion from mouse pancreatic islets , which can be used to study obesity.</p>
    Purity:98.41%
    Color and Shape:Odour Solid
  • Bay 55-9837

    CAS:
    <p>Selective VPAC2 agonist; EC50: 0.4 nM (VPAC2), 100 nM (VPAC1), &gt;1000 nM (PAC1). Enhances insulin secretion, reduces HIV-1 replication.</p>
    Formula:C167H270N52O46
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3742.29
  • Semaglutide TFA


    <p>Semaglutide TFA is a glucagon-like peptide-1 congener that induces weight loss, lowers blood glucose levels and reduces cardiovascular risk in diabetic patients</p>
    Formula:C189H290F3N45O61
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:4225.6482
  • Survodutide

    CAS:
    <p>Survodutide (BI 456906) is a dual agonist of glucagon and glucagon-like peptide 1 (GLP-1) receptor (GLP Receptor) that reduces body weight in HbA1c16 diabetes.</p>
    Formula:C192H289N47O61
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:4229.0957
  • VU0453379 hydrochloride


    <p>VU0453379 hydrochloride: selective CNS-penetrant GLP-1R PAM, EC50 1.3 μM.</p>
    Formula:C26H35ClN4O2
    Color and Shape:Solid
    Molecular weight:471.03
  • 3-Deoxyglucosone

    CAS:
    <p>3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein</p>
    Formula:C6H10O5
    Purity:95%
    Color and Shape:Solid
    Molecular weight:162.14
  • Sorbinicate

    CAS:
    <p>Sorbinicate is an antihypercholesterolaemic and vasodilating nicotinic acid ester.</p>
    Formula:C42H32N6O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:812.74
  • Albiglutide fragment TFA


    <p>Albiglutide fragment (GLP-1 (7-36) analog) TFA represents a biologically active segment of Albiglutide, resistant to DPP-4 degradation due to its structure as a</p>
    Formula:C148H224N40O45·xC2HF3O2
    Color and Shape:Solid
  • (R)-V-0219 hydrochloride


    <p>(R)-V-0219 hydrochloride: Oral GLP-1R PAM, enantiomer of V-0219, triggers Ca2+ flux in hGLP-1R HEK cells.</p>
    Formula:C20H26ClF3N4O2
    Color and Shape:Solid
    Molecular weight:446.89
  • Maridebart

    CAS:
    <p>Maridebart is a humanized IgG1-kappa monoclonal antibody that targets the GIPR (gastric inhibitory polypeptide receptor) [1].</p>
    Color and Shape:Liquid
  • Oxyntomodulin

    CAS:
    <p>GLP-1 analog modulates appetite, boosts metabolism, and curbs gastric acid. Increases cAMP, mildly stimulates glucagon receptor.</p>
    Formula:C192H295N59O60S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4421.86
  • GLP-1 receptor agonist 8

    CAS:
    <p>GLP-1 receptor agonist 8, potent for diabetes and obesity research, may also study NAFLD.</p>
    Formula:C34H36ClFN6O4
    Color and Shape:Solid
    Molecular weight:647.14
  • [Des-His1,Glu9]-Glucagon amide

    CAS:
    <p>Glucagon blocker with pA2 of 7.2; no agonist effect. Boosts insulin; prevents glucagon-driven hyperglycemia in rabbits and diabetic rats.</p>
    Formula:C148H221N41O47S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3358.68
  • GLP-1R agonist 27


    <p>GLP-1R agonist 27 (compound 21) is a potent and orally active GLP-1R agonist. It enhances the accumulation of cyclic adenosine monophosphate (cAMP), reduces blood glucose levels, and decreases food intake. GLP-1R agonist 27 shows potential for research in obesity and type 2 diabetes mellitus (T2DM).</p>
    Formula:C32H33N5O4Se
    Color and Shape:Solid
    Molecular weight:630.6
  • (S)-V-0219 hydrochloride


    <p>(S)-V-0219 hydrochloride, a GLP-1R PAM, triggers calcium in hGLP-1R HEK cells, lowers glucose in mice, and reduces fasting hunger.</p>
    Formula:C20H26ClF3N4O2
    Color and Shape:Solid
    Molecular weight:446.89
  • GLP-1R agonist 15

    CAS:
    <p>GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .</p>
    Formula:C46H47FN8O7S
    Color and Shape:Solid
    Molecular weight:874.98
  • Gulgafafusp alfa

    CAS:
    <p>Gulgafafusp alfa is a human IgG2κ monoclonal antibody that selectively binds to the glucagon-like peptide 1 receptor (GLP1R) [1].</p>
    Color and Shape:Liquid
  • Anti-GLP-1R Antibody


    <p>Anti-GLP-1R Antibody is an anti-GLP-1R antibody that can be used for immunohistochemistry of paraffin sections.</p>
    Purity:98.3% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.3% (SDS-PAGE); 97.2% (SEC-HPLC)
    Color and Shape:Odour Liquid
  • SPN009


    <p>SPN009 (Sequence 3) is a GLP-1 receptor (GLP-1 Receptor) agonist, with an EC50 of 2.84 nM, and improves type 2 diabetes in DB/DB mouse models.</p>
    Formula:C191H299N45O59
    Molecular weight:4167.17798
  • Glucagon-like peptide 1 (1-37), human TFA


    <p>Human Glucagon-like peptide 1 (1-37) TFA is a potent GLP-1 receptor agonist derived from proglucagon.</p>
    Formula:C188H276N51F3O61
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4283.5
  • GLP-1R agonist 20


    <p>GLP-1R agonist 20 (Compound I-132) is an agonist of the glucagon-like peptide-1 receptor (GLP-1 receptor), with an EC50 value of 0.0162 nM.</p>
    Formula:C31H30Cl2F2N4O5
    Molecular weight:646.15613
  • GLP-1R agonist 16

    CAS:
    <p>Compound 115a, a GLP-1R agonist, effectively activates the GLP-1 receptor with an EC50 of 0.15 nM [1].</p>
    Formula:C50H58FN10O6P
    Color and Shape:Solid
    Molecular weight:945.03
  • GLP-1R agonist 4

    CAS:
    <p>GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.</p>
    Formula:C32H30ClF2N3O5
    Color and Shape:Solid
    Molecular weight:610.05
  • SAR441255


    <p>SAR441255 is a potent unimolecular peptide that acts as a GLP-1/GIP/GCG receptor triagonist, demonstrating balanced activation across all three target receptors</p>
    Color and Shape:Odour Solid
  • FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS


    <p>FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.</p>
    Color and Shape:Solid
    Molecular weight:3692.15
  • Dapiglutide

    CAS:
    <p>Dapiglutide (ZP7570) is a long-acting GLP-1R &amp; GLP-2R dual agonist for SBS research.</p>
    Color and Shape:Solid
  • GRPP (human)

    CAS:
    <p>GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations.</p>
    Formula:C136H215N41O58S
    Color and Shape:Solid
    Molecular weight:3384.47
  • Glucagon (1-29), bovine, human, porcine

    CAS:
    <p>Corynoxine B (Cory B) is a naturally occurring alkaloid isolated from Uncaria rhynchophylla (Miq. ) and is an autophagy inducer.</p>
    Formula:C153H225N43O49S
    Purity:99.56% - 99.56%
    Color and Shape:Solid
    Molecular weight:3482.75
  • GLP-1 receptor agonist 7

    CAS:
    <p>GLP-1 receptor agonist 7, potential for diabetes research, from patent WO2021219019A1.</p>
    Formula:C31H30ClFN4O5
    Color and Shape:Solid
    Molecular weight:593.05
  • GLP-1 receptor agonist 2

    CAS:
    <p>GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>
    Formula:C30H31ClFN5O4
    Color and Shape:Solid
    Molecular weight:580.05
  • V-0219

    CAS:
    <p>V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.</p>
    Formula:C20H25F3N4O2
    Purity:99.91%
    Color and Shape:Soild
    Molecular weight:410.43
  • GLP-1R modulator C16

    CAS:
    <p>GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.</p>
    Formula:C21H26ClFN2O3
    Purity:99.6% - >99.99%
    Color and Shape:Solid
    Molecular weight:408.89