CymitQuimica logo
Dopamine Receptor

Dopamine Receptor

Dopamine receptors are a group of GPCRs that respond to the neurotransmitter dopamine, playing a key role in the regulation of movement, motivation, reward, and several cognitive functions. These receptors are divided into D1-like and D2-like families, each with distinct functions and pharmacological profiles. Dopamine receptor modulators are widely studied for their applications in treating Parkinson's disease, schizophrenia, addiction, and other neuropsychiatric disorders. At CymitQuimica, we offer a wide range of high-quality dopamine receptor modulators to support your research in neuroscience, mental health, and GPCR signaling.

Found 433 products of "Dopamine Receptor"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Timiperone
    Targetmol
    + Info

    Timiperone

    CAS:
    Timiperone exhibits a high affinity for cerebral dopamine D2 receptors, demonstrating antipsychotic activity as it mitigates stereotyped behavior.
    Formula:C22H24FN3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:397.51

    Ref: TM-T78514

  • SKF 81297
    Targetmol
    + Info

    SKF 81297

    CAS:
    <p>SKF 81297 is a selective and potent agonist for the dopamine D1 receptor [1].</p>
    Formula:C16H16ClNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:289.76

    Ref: TM-T81152

  • Quinpirole dihydrochloride
    Targetmol
    + Info

    Quinpirole dihydrochloride

    CAS:
    <p>Quinpirole dihydrochloride is an agonist of the D2-like dopamine receptor.</p>
    Formula:C13H23Cl2N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:292.25

    Ref: TM-T24696

  • Dihydrexidine
    Targetmol
    + Info

    Dihydrexidine

    CAS:
    <p>Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.</p>
    Formula:C17H17NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:267.32

    Ref: TM-T13463L

  • Sonepiprazole
    Targetmol
    + Info

    Sonepiprazole

    CAS:
    Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation
    Formula:C21H27N3O3S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:401.52

    Ref: TM-T23380

  • SKF 81297 hydrobromide
    Targetmol
    + Info

    SKF 81297 hydrobromide

    CAS:
    SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.
    Formula:C16H17BrClNO2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:370.67

    Ref: TM-T23361

  • PAOPA
    Targetmol
    + Info

    PAOPA

    CAS:
    dopamine D2 receptor modulator
    Formula:C11H18N4O3
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:254.29

    Ref: TM-T23121

  • NMI 8739
    Targetmol
    + Info

    NMI 8739

    CAS:
    <p>NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor.</p>
    Formula:C30H41NO3
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:463.65

    Ref: TM-T11079

  • Lumateperone
    Targetmol
    + Info

    Lumateperone

    CAS:
    <p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>
    Formula:C24H28FN3O
    Purity:99.68% - 99.91%
    Color and Shape:Solid
    Molecular weight:393.5

    Ref: TM-T21069

  • Disulergine
    Targetmol
    + Info

    Disulergine

    CAS:
    Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.
    Formula:C17H24N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.46

    Ref: TM-T24003

  • D1R antagonist 1
    Targetmol
    + Info

    D1R antagonist 1

    CAS:
    <p>Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].</p>
    Formula:C22H26BrNO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:448.35

    Ref: TM-T78735

  • Dopamine D4 receptor ligand 3
    Targetmol
    + Info

    Dopamine D4 receptor ligand 3

    CAS:
    Dopamine D4 receptor ligand 3 (Compound 16) functions as a dopamine D4 receptor (D4R) antagonist with a pKi of 8.86. In HEK-293T cells, it shows pIC50 values of 5.78, 5.55, and 6.17 for Go, Gi, and βArr2 sensors, respectively. This compound inhibits the activity of human glioma cell lines U87 MG, T98G, and U251 MG, and it induces ROS production and mitochondrial dysfunction in these glioma cells.
    Formula:C28H31N3O5
    Color and Shape:Solid
    Molecular weight:489.56

    Ref: TM-T207369

  • U91356
    Targetmol
    + Info

    U91356

    CAS:
    U91356 is an agonist of the dopamine receptors.
    Formula:C13H17N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:231.29

    Ref: TM-T13240

  • Neflumozide
    Targetmol
    + Info

    Neflumozide

    CAS:
    Neflumozide (HRP 913) is an orally effective derivative of benzisoxazole, characterized by its potent dopamine antagonist properties and antipsychotic activity. It is utilized in research related to psychiatric disorders.
    Formula:C22H23FN4O2
    Color and Shape:Solid
    Molecular weight:394.44

    Ref: TM-T201050

  • CymitQuimica logo
    Targetmol
    + Info

    Dopamine D3 receptor antagonist-1

    <p>Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic</p>
    Formula:C31H35Cl2N3O3
    Color and Shape:Solid
    Molecular weight:568.53

    Ref: TM-T64024

  • LY3154207
    Targetmol
    + Info

    LY3154207

    CAS:
    LY3154207: selective, potent oral human dopamine D1 receptor PAM, low agonist activity, EC50=3 nM.
    Formula:C24H29Cl2NO3
    Color and Shape:Solid
    Molecular weight:450.4

    Ref: TM-T11912

  • RS 12254
    Targetmol
    + Info

    RS 12254

    CAS:
    RS 12254 is a dopamine agonist and antihypertensive agent.
    Formula:C28H40N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.63

    Ref: TM-T26131

  • UNC10099984A
    Targetmol
    + Info

    UNC10099984A

    CAS:
    UNC10099984A (Compound 6) is a functionally selective ligand for the dopamine D2 receptor, exhibiting a Ki value of 4.6 nM and an EC50 of 6.2 nM for β-arrestin. This compound is useful for research into central nervous system diseases related to the D2 receptor.
    Formula:C24H29Cl2N3O2
    Color and Shape:Solid
    Molecular weight:462.41

    Ref: TM-T201623

  • 9-Methyl-β-carboline
    Targetmol
    + Info

    9-Methyl-β-carboline

    CAS:
    9-Methyl-β-carboline is a cognitive enhancer with neuroprotective, neurorestorative, and anti-inflammatory properties. Its behavioral effects may be linked to hippocampal dopamine levels and the stimulation of dendritic and synaptic proliferation.
    Formula:C12H10N2
    Color and Shape:Solid
    Molecular weight:182.221

    Ref: TM-T204669

  • Dinoxyline
    Targetmol
    + Info

    Dinoxyline

    CAS:
    <p>Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.</p>
    Formula:C15H13NO3
    Color and Shape:Solid
    Molecular weight:255.27

    Ref: TM-T201856

  • CM699
    Targetmol
    + Info

    CM699

    CAS:
    <p>CM699 is an effective dual inhibitor of the dopamine transporter (DAT) and Sigma receptor (σR), with IC50 values of 311 nM and 14.1 nM, respectively.</p>
    Formula:C24H29N3O2
    Color and Shape:Solid
    Molecular weight:391.51

    Ref: TM-T207261

  • CymitQuimica logo
    Targetmol
    + Info

    Dopamine D3 receptor ligand-1

    Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:
    Formula:C27H29N5O
    Color and Shape:Solid
    Molecular weight:439.55

    Ref: TM-T62528

  • CymitQuimica logo
    Targetmol
    + Info

    Dopamine D3 receptor antagonist-2

    Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.
    Formula:C23H27Cl2N3O3
    Color and Shape:Solid
    Molecular weight:464.38

    Ref: TM-T62946

  • RG-15
    Targetmol
    + Info

    RG-15

    CAS:
    RG-15 is an orally active dopamine receptor antagonist with high affinity for the human D2 receptor (pKi of 8.23) and human D3 receptor (pKi of 10.49). It inhibits dopamine-stimulated [35S]GTPγS binding with IC50 values of 21.2 nM in rat striatal membranes, 36.7 nM in mouse A9 cells expressing human D2L receptors, and 7.2 nM in CHO cells expressing human D3 receptors. RG-15 enhances dopamine turnover and synthesis in the striatum and olfactory bulb of mice, exhibiting antipsychotic activity.
    Formula:C25H32Cl2F3N5O2S
    Color and Shape:Solid
    Molecular weight:594.52

    Ref: TM-T206486

  • CymitQuimica logo
    Targetmol
    + Info

    D4R antagonist-1

    <p>Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.</p>
    Formula:C21H25F2NO2
    Color and Shape:Solid
    Molecular weight:361.43

    Ref: TM-T61347

  • NMDAR antagonist 5
    Targetmol
    + Info

    NMDAR antagonist 5

    CAS:
    NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.
    Formula:C17H21N3
    Color and Shape:Solid
    Molecular weight:267.369

    Ref: TM-T206943

  • Quinagolide Free Base
    Targetmol
    + Info

    Quinagolide Free Base

    CAS:
    Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.
    Formula:C20H33N3O3S
    Color and Shape:Solid
    Molecular weight:395.56

    Ref: TM-T68483

  • CymitQuimica logo
    Targetmol
    + Info

    D4R antagonis-2

    Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.
    Formula:C21H23ClF2N2O2
    Color and Shape:Solid
    Molecular weight:408.87

    Ref: TM-T62054

  • Lisuride
    Targetmol
    + Info

    Lisuride

    CAS:
    Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.
    Formula:C20H26N4O
    Color and Shape:Solid
    Molecular weight:338.45

    Ref: TM-T61065

  • Cendifensine
    Targetmol
    + Info

    Cendifensine

    CAS:
    <p>Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).</p>
    Formula:C14H17Cl2NO
    Color and Shape:Solid
    Molecular weight:286.197

    Ref: TM-T206480

  • 3-Hydroxybenzylamine
    Targetmol
    + Info

    3-Hydroxybenzylamine

    CAS:
    <p>3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.</p>
    Formula:C7H9NO
    Color and Shape:Solid
    Molecular weight:123.155

    Ref: TM-T124305

    ne
    Discontinued
    Discontinued product
  • 6-Chloro-5-(2-chloroethyl)indolin-2-one
    Targetmol
    + Info

    6-Chloro-5-(2-chloroethyl)indolin-2-one

    CAS:
    6-Chloro-5-(2-chloroethyl)indolin-2-one is a useful organic compound for research related to life sciences. The catalog number is T64862 and the CAS number is 118289-55-7.
    Formula:C10H9Cl2NO
    Color and Shape:Solid
    Molecular weight:230.09

    Ref: TM-T64862

    ne
    Discontinued
    Discontinued product
  • GR 218,231
    Targetmol
    + Info

    GR 218,231

    CAS:
    GR 218,231 is a selective antagonist of D3 dopamine receptor.
    Formula:C24H33NO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:415.59

    Ref: TM-T27431

    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product