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Dopamine Receptor

Dopamine Receptor

Dopamine receptors are a group of GPCRs that respond to the neurotransmitter dopamine, playing a key role in the regulation of movement, motivation, reward, and several cognitive functions. These receptors are divided into D1-like and D2-like families, each with distinct functions and pharmacological profiles. Dopamine receptor modulators are widely studied for their applications in treating Parkinson's disease, schizophrenia, addiction, and other neuropsychiatric disorders. At CymitQuimica, we offer a wide range of high-quality dopamine receptor modulators to support your research in neuroscience, mental health, and GPCR signaling.

Found 407 products of "Dopamine Receptor"

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  • SKF 81297 hydrobromide

    CAS:
    <p>SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor,exhibits central activity and is widely used to study the neuromodulatory effects.</p>
    Formula:C16H17BrClNO2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:370.67
  • CP-293019

    CAS:
    <p>CP-293019 is a potent, selective antagonist of dopamine D4 receptor.</p>
    Formula:C19H22F2N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.4
  • 4-Amino-PPHT Hydrobromide

    CAS:
    <p>4-Amino-PPHT Hydrobromide is a precursor for fluorescent labeled Dopamine D2 receptors agonist.</p>
    Formula:C21H28N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.46
  • PAOPA

    CAS:
    <p>dopamine D2 receptor modulator</p>
    Formula:C11H18N4O3
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:254.29
  • NMI 8739

    CAS:
    <p>NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor.</p>
    Formula:C30H41NO3
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:463.65
  • Lumateperone

    CAS:
    <p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>
    Formula:C24H28FN3O
    Purity:99.68% - 99.91%
    Color and Shape:Solid
    Molecular weight:393.5
  • Dopamine D3 receptor antagonist-1


    <p>Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic</p>
    Formula:C31H35Cl2N3O3
    Color and Shape:Solid
    Molecular weight:568.53
  • D4R antagonist-1


    <p>Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.</p>
    Formula:C21H25F2NO2
    Color and Shape:Solid
    Molecular weight:361.43
  • CM699

    CAS:
    <p>CM699 is an effective dual inhibitor of the dopamine transporter (DAT) and Sigma receptor (σR), with IC50 values of 311 nM and 14.1 nM, respectively.</p>
    Formula:C24H29N3O2
    Color and Shape:Solid
    Molecular weight:391.51
  • Dopamine D3 receptor ligand-1


    <p>Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:</p>
    Formula:C27H29N5O
    Color and Shape:Solid
    Molecular weight:439.55
  • D1R antagonist 1

    CAS:
    <p>Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].</p>
    Formula:C22H26BrNO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:448.35
  • Dopamine D3 receptor antagonist-2


    <p>Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.</p>
    Formula:C23H27Cl2N3O3
    Color and Shape:Solid
    Molecular weight:464.38
  • UNC10099984A

    CAS:
    <p>UNC10099984A (Compound 6) is a functionally selective ligand for the dopamine D2 receptor, exhibiting a Ki value of 4.6 nM and an EC50 of 6.2 nM for β-arrestin. This compound is useful for research into central nervous system diseases related to the D2 receptor.</p>
    Formula:C24H29Cl2N3O2
    Color and Shape:Solid
    Molecular weight:462.41
  • Neflumozide

    CAS:
    <p>Neflumozide (HRP 913) is an orally effective derivative of benzisoxazole, characterized by its potent dopamine antagonist properties and antipsychotic activity. It is utilized in research related to psychiatric disorders.</p>
    Formula:C22H23FN4O2
    Color and Shape:Solid
    Molecular weight:394.44
  • NMDAR antagonist 5

    CAS:
    <p>NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50&gt; 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.</p>
    Formula:C17H21N3
    Color and Shape:Solid
    Molecular weight:267.369
  • D4R antagonis-2


    <p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>
    Formula:C21H23ClF2N2O2
    Color and Shape:Solid
    Molecular weight:408.87
  • Lisuride

    CAS:
    <p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>
    Formula:C20H26N4O
    Color and Shape:Solid
    Molecular weight:338.45
  • Cendifensine

    CAS:
    <p>Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).</p>
    Formula:C14H17Cl2NO
    Color and Shape:Solid
    Molecular weight:286.197
  • Disulergine

    CAS:
    <p>Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.</p>
    Formula:C17H24N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.46
  • Dinoxyline

    CAS:
    <p>Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.</p>
    Formula:C15H13NO3
    Color and Shape:Solid
    Molecular weight:255.27