GTPase
GTPases are a family of enzymes that hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP), playing a crucial role in signal transduction pathways, including those mediated by GPCRs. GTPases act as molecular switches in various cellular processes, such as cell division, growth, and differentiation. Dysregulation of GTPase activity is implicated in numerous diseases, including cancer and genetic disorders. At CymitQuimica, we offer a selection of high-quality GTPase modulators to support your research in cell signaling, cancer biology, and GPCR-related pathways.
Found 23 products of "GTPase"
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PT-129
PT-129 is a PROTAC degrader targeting the NTF2 domain of G3BP1/2, degrading stress granules in stressed cells, suppressing proliferation.Formula:C46H48N8O12SColor and Shape:SolidMolecular weight:936.98RGS2-Galpha-q interaction-IN-1
RGS2–Galpha-q interaction-IN-1 (Compound AJ-3) is an inhibitor of the RGS2-Galpha-q interaction. It inhibits the growth of cancer cell lines that express RGS2 and has anti-cell migration properties.Formula:C30H30ClN7O3Color and Shape:SolidMolecular weight:572.06Myristoylated ARF6 (2-13)
Myristoylated ARF6 (2-13) inhibits the MyD88–ARNO–ARF6 signaling axis by inactivating ARF6.Formula:C74H128N16O18Molecular weight:1528.95925CID-1067700
CAS:CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).Formula:C18H18N2O4S2Purity:99.46%Color and Shape:SolidMolecular weight:390.48Ref: TM-T7558
1mg34.00€2mg49.00€5mg71.00€10mg105.00€25mg178.00€50mg234.00€100mg303.00€1mL*10mM (DMSO)78.00€Exo-1
CAS:Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, asFormula:C15H12FNO3Purity:99.45%Color and Shape:SolidMolecular weight:273.26Ref: TM-T9200
5mg52.00€10mg78.00€25mg119.00€50mg172.00€100mg259.00€200mg388.00€500mg642.00€1mL*10mM (DMSO)65.00€BQU57
CAS:BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.Formula:C16H13F3N4OPurity:97.45% - 98.72%Color and Shape:SolidMolecular weight:334.3CCG-50014
CAS:CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.Formula:C16H13FN2O2SPurity:98.53%Color and Shape:SolidMolecular weight:316.35Exo1
CAS:Exo1 is an inhibitor of the exocytic pathwayFormula:C15H12FNO3Purity:98.75%Color and Shape:SolidMolecular weight:273.26MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg34.00€5mg50.00€10mg86.00€25mg161.00€50mg245.00€100mg363.00€200mg515.00€1mL*10mM (DMSO)55.00€NAV-2729
CAS:NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.Formula:C25H17ClN4O3Purity:98.83% - 98.91%Color and Shape:SolidMolecular weight:456.88Ref: TM-T5142
2mg43.00€5mg63.00€10mg90.00€25mg193.00€50mg286.00€100mg429.00€500mg888.00€1mL*10mM (DMSO)71.00€RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Formula:C25H20N4O3Purity:98.44% - 99.81%Color and Shape:SolidMolecular weight:424.45Ref: TM-T6634
1mg48.00€5mg92.00€10mg156.00€25mg298.00€50mg472.00€100mg687.00€200mg938.00€1mL*10mM (DMSO)97.00€ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139Ref: TM-T21970
5mg62.00€10mg90.00€25mg133.00€50mg192.00€100mg286.00€500mg687.00€1mL*10mM (DMSO)67.00€Dynamin inhibitory peptide Acetate
Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.Formula:C49H84N18O16Purity:97.28%Color and Shape:SolidMolecular weight:1181.3Ref: TM-T21798L
1mg73.00€5mg198.00€10mg294.00€25mg467.00€50mg642.00€100mg853.00€1mL*10mM (DMSO)474.00€QS11
CAS:QS11, a GTPase ARFGAP1, modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation.Formula:C36H33N5O2Purity:98.59%Color and Shape:SolidMolecular weight:567.68Ref: TM-T4022
2mg34.00€5mg50.00€10mg80.00€25mg147.00€50mg215.00€100mg323.00€200mg442.00€1mL*10mM (DMSO)62.00€Bragsin1
CAS:Bragsin1 is a potent and selective and noncompetitive ArfGEF BRAG2 inhibitor, inhibits Arf GTPase activation(IC50 : 3 μM),and with anti-cancer activity.Formula:C11H6F3NO4Color and Shape:SolidMolecular weight:273.16CCG-4986
CAS:CCG-4986 is the first small molecule RGS inhibitor reported that directly bound to an RGS protein.Formula:C13H11ClN2O5S2Color and Shape:SolidMolecular weight:374.82CCG-2046
CAS:CCG-2046 is a chemical inhibitor targeting RGS4, demonstrating an inhibition concentration (IC50) of 4.3 μM for the interaction between RGS4 and Gαo signal.Formula:C11H10N4Color and Shape:SolidMolecular weight:198.22Compound C108
CAS:Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).
Formula:C15H14N2O3Purity:99.77%Color and Shape:SolidMolecular weight:270.28CCG-63802
CAS:CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.Formula:C26H18N4O2SPurity:90%Color and Shape:SolidMolecular weight:450.51RBC10
CAS:RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-Formula:C24H25ClN2O2Purity:99.71%Color and Shape:SolidMolecular weight:408.92Ref: TM-T24706
1mg33.00€2mg49.00€5mg75.00€10mg110.00€25mg245.00€50mg354.00€100mg515.00€200mg700.00€1mL*10mM (DMSO)81.00€
