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GTPase

GTPase

GTPases are a family of enzymes that hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP), playing a crucial role in signal transduction pathways, including those mediated by GPCRs. GTPases act as molecular switches in various cellular processes, such as cell division, growth, and differentiation. Dysregulation of GTPase activity is implicated in numerous diseases, including cancer and genetic disorders. At CymitQuimica, we offer a selection of high-quality GTPase modulators to support your research in cell signaling, cancer biology, and GPCR-related pathways.

Found 21 products of "GTPase"

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  • CymitQuimica logo
    Targetmol
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    Myristoylated ARF6 (2-13)

    <p>Myristoylated ARF6 (2-13) inhibits the MyD88–ARNO–ARF6 signaling axis by inactivating ARF6.</p>
    Formula:C74H128N16O18
    Molecular weight:1528.95925

    Ref: TM-TP3490

  • CymitQuimica logo
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    RGS2-Galpha-q interaction-IN-1

    <p>RGS2–Galpha-q interaction-IN-1 (Compound AJ-3) is an inhibitor of the RGS2-Galpha-q interaction. It inhibits the growth of cancer cell lines that express RGS2 and has anti-cell migration properties.</p>
    Formula:C30H30ClN7O3
    Color and Shape:Solid
    Molecular weight:572.06

    Ref: TM-T200859

  • RBC8
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    RBC8

    CAS:
    <p>RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.</p>
    Formula:C25H20N4O3
    Purity:98.44% - 99.81%
    Color and Shape:Solid
    Molecular weight:424.45

    Ref: TM-T6634

  • NAV-2729
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    NAV-2729

    CAS:
    <p>NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.</p>
    Formula:C25H17ClN4O3
    Purity:98.83% - 98.91%
    Color and Shape:Solid
    Molecular weight:456.88

    Ref: TM-T5142

  • Exo-1
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    Exo-1

    CAS:
    <p>Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, as</p>
    Formula:C15H12FNO3
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:273.26

    Ref: TM-T9200

  • BQU57
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    BQU57

    CAS:
    <p>BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.</p>
    Formula:C16H13F3N4O
    Purity:97.45% - 98.72%
    Color and Shape:Solid
    Molecular weight:334.3

    Ref: TM-T2267

  • ML-097
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    ML-097

    CAS:
    <p>ML-097 (CID-2160985) is a pan activator of Ras-related GTPases</p>
    Formula:C14H11BrO3
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:307.139

    Ref: TM-T21970

  • Dynamin inhibitory peptide Acetate
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    Dynamin inhibitory peptide Acetate

    <p>Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.</p>
    Formula:C49H84N18O16
    Purity:97.28%
    Color and Shape:Solid
    Molecular weight:1181.3

    Ref: TM-T21798L

  • CCG-50014
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    CCG-50014

    CAS:
    <p>CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.</p>
    Formula:C16H13FN2O2S
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:316.35

    Ref: TM-T6434

  • CID-1067700
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    CID-1067700

    CAS:
    <p>CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).</p>
    Formula:C18H18N2O4S2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:390.48

    Ref: TM-T7558

  • MLS-573151
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    MLS-573151

    CAS:
    <p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>
    Formula:C21H19N3O2S
    Purity:98.80%
    Color and Shape:Solid
    Molecular weight:377.46

    Ref: TM-T22106

  • Bragsin1
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    Bragsin1

    CAS:
    <p>Bragsin1 is a potent and selective and noncompetitive ArfGEF BRAG2 inhibitor, inhibits Arf GTPase activation(IC50 : 3 μM),and with anti-cancer activity.</p>
    Formula:C11H6F3NO4
    Color and Shape:Solid
    Molecular weight:273.16

    Ref: TM-T14774

  • CCG-4986
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    CCG-4986

    CAS:
    <p>CCG-4986 is the first small molecule RGS inhibitor reported that directly bound to an RGS protein.</p>
    Formula:C13H11ClN2O5S2
    Color and Shape:Solid
    Molecular weight:374.82

    Ref: TM-T68820

  • QS11
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    QS11

    CAS:
    <p>QS11, a GTPase ARFGAP1, modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation.</p>
    Formula:C36H33N5O2
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:567.68

    Ref: TM-T4022

  • CCG-2046
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    CCG-2046

    CAS:
    <p>CCG-2046 is a chemical inhibitor targeting RGS4, demonstrating an inhibition concentration (IC50) of 4.3 μM for the interaction between RGS4 and Gαo signal.</p>
    Formula:C11H10N4
    Color and Shape:Solid
    Molecular weight:198.22

    Ref: TM-T73348

  • Compound C108
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    Compound C108

    CAS:
    <p>Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).</p>
    Formula:C15H14N2O3
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:270.28

    Ref: TM-T38387

  • RBC10
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    RBC10

    CAS:
    <p>RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-</p>
    Formula:C24H25ClN2O2
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:408.92

    Ref: TM-T24706

  • CCG-63808
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    CCG-63808

    CAS:
    <p>CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.</p>
    Formula:C25H15FN4O2S
    Purity:90%
    Color and Shape:Solid
    Molecular weight:454.48

    Ref: TM-T14898

  • CCG-63802
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    CCG-63802

    CAS:
    <p>CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.</p>
    Formula:C26H18N4O2S
    Purity:90%
    Color and Shape:Solid
    Molecular weight:450.51

    Ref: TM-T14897

  • Anti-inflammatory agent 49
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    Anti-inflammatory agent 49

    CAS:
    <p>Compound SC9, an anti-inflammatory agent, serves as a potent and selective inhibitor of the Drp1-Fis1 interaction, mitigating FIS1-mediated mitochondrial</p>
    Formula:C21H22N8O3S
    Purity:99.56% - 99.74%
    Color and Shape:Solid
    Molecular weight:466.52

    Ref: TM-T83057