GPCR19
GPCR19, also known as GPR19, is a member of the G protein-coupled receptor family with roles that are still being elucidated in various physiological processes. Although less characterized than other GPCRs, GPCR19 is of interest in research focused on discovering new therapeutic targets for metabolic diseases, cancer, and neurological disorders. At CymitQuimica, we offer a selection of research tools and reagents to support your investigations into the functions and potential therapeutic applications of GPCR19.
Found 36 products of "GPCR19"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BAR501
CAS:BAR501是高效选择性的 GPBAR1激动剂(EC50:1 μM)。Formula:C26H46O3Purity:99.29% - 99.68%Color and Shape:SolidMolecular weight:406.64SBI-115
CAS:SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5Formula:C14H13ClN2O4SPurity:99.53% - 99.78%Color and Shape:SolidMolecular weight:340.78PEN (human) aceate
PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.Formula:C99H163N27O34Purity:99.25%Color and Shape:SolidMolecular weight:2275.51Deoxycholic acid sodium salt
CAS:Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates BAT thermogenic activity.Formula:C24H39NaO4Purity:97.88% - 99.84%Color and Shape:Cream Crystalline PowderMolecular weight:414.56CAY10789
CAS:CAY10789: potent CysLT1R antagonist (IC50 2.8 µM), GPBAR1 agonist (EC50 3 µM), reduces U937 cell adhesion, TNF-α, stable with promising pharmacokinetics.Formula:C17H15NO2Color and Shape:SolidMolecular weight:265.31WB403
CAS:WB403 activates TGR5, lowers fasting/postprandial glucose and HbA1c, enhances glucose tolerance, and normalizes pancreatic α/β-cells in diabetic mice.Formula:C19H19BrN2OSPurity:98%Color and Shape:SolidMolecular weight:403.34TGR5 Receptor Agonist 4
CAS:TGR5 Receptor Agonist 4, a selective agonist for the Bile Acid Receptor (TGR5), exhibits potent activity with an EC50 of 2 nM for human TGR5 (hTGR5) and 3 nMFormula:C25H27ClN2O5Color and Shape:SolidMolecular weight:470.95INT-777 R-enantiomer
CAS:INT-777 is the R-enantiomer of INT-777, less potent than INT-777,EC50 of 4.79 μM for TGR5.Formula:C27H46O5Purity:98%Color and Shape:SolidMolecular weight:450.65RO5527239
CAS:RO5527239 is a potent, orally available GPBAR1 agonist agent.Formula:C28H31N3O3Purity:98%Color and Shape:SolidMolecular weight:457.56TGR5 agonist 3
CAS:Compound 8, a cholic acid derivative, functions as a selective TGR5 agonist and exhibits an EC50 value of 5 μM [1].Formula:C28H48O5Color and Shape:SolidMolecular weight:464.68INT-777
CAS:INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM.Formula:C27H46O5Purity:99.78%Color and Shape:SolidMolecular weight:450.65Ref: TM-T11662L
1mg130.00€5mg313.00€1mL*10mM (DMSO)343.00€10mg447.00€25mg715.00€50mg999.00€100mg1,395.00€5-HT7R antagonist 1
5-HT7R antagonist 1 is a G protein-biased antagonist with Ki of 6.5 nM for 5-HT 7R.Formula:C14H18Cl2N4Color and Shape:SolidMolecular weight:313.23GPBAR1-IN-3
CAS:GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].Formula:C21H23NO2Color and Shape:SolidMolecular weight:321.41LT-188A
CAS:LT-188A is a potent TGR5 agonist with an EC50 value of 23 μM. It effectively reduces levels of inflammatory mediators in macrophages.Formula:C28H36O7Color and Shape:SolidMolecular weight:484.585β-Cholestane-3α,7α,12α,25-tetrol
CAS:5β-Cholestane-3α,7α,12α,25-tetrol is a type of bile acid alcohol that activates the G protein-coupled bile acid receptor 1 (GPBAR1), also known as TGR5, in HEK293 cells that express the human receptor, at concentrations between 0.1 to 10 µM. In individuals with cerebrotendinous xanthomatosis (CTX), a progressive metabolic leukodystrophy, levels of this compound are elevated in the blood, feces, and bile.Formula:C27H48O4Color and Shape:SolidMolecular weight:436.67TGR5 Receptor Agonist 3
CAS:TGR5 Receptor Agonist 3 is a GPBAR1 agonist with EC50 of 16.4 nM (hTGR5) & 209 nM (mTGR5), ensures gallbladder safety and reduces filling.Formula:C29H27N3O6Color and Shape:SolidMolecular weight:513.54
