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PAFR

PAFR

The platelet-activating factor receptor (PAFR) is a GPCR that binds to platelet-activating factor (PAF), a potent phospholipid mediator involved in inflammation, thrombosis, and allergic responses. PAFR signaling plays a critical role in immune responses, cardiovascular health, and the pathogenesis of inflammatory diseases. Modulation of PAFR activity is of interest in the development of anti-inflammatory and antithrombotic therapies. At CymitQuimica, we offer a variety of high-quality PAFR modulators to support your research in immunology, cardiovascular biology, and inflammation.

Found 11 products of "PAFR"

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  • PAF C-18
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    PAF C-18

    CAS:
    <p>PAF C-18 is a natural phospholipid molecule belonging to the platelet-activating factor (PAF) family,, involved in hemostasis and thrombosis by binding to PAFR.</p>
    Formula:C28H58NO7P
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:551.74

    Ref: TM-T36763

  • α-Bulnesene
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    α-Bulnesene

    CAS:
    <p>α-Bulnesene, a novel PAF (platelet-activating factor) receptor antagonist, exhibits an IC50 of 17.62 μM. It can be isolated from patchouli. α-Bulnesene inhibits both PAF and arachidonic acid-induced aggregation of rabbit platelets.</p>
    Formula:C15H24
    Color and Shape:Solid
    Molecular weight:204.35

    Ref: TM-TN8025

  • Tulopafant
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    Tulopafant

    CAS:
    <p>Tulopafant (RP 59227) is a potent platelet-activating factor (PAF) antagonist that increases capillary patency and prolongs allograft heart survival.</p>
    Formula:C25H19N3O2S
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:425.5

    Ref: TM-T17178

  • PAF-AN-1
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    PAF-AN-1

    CAS:
    <p>PAF-AN-1 is a novel potent platelet-activating factor receptor (PAF) antagonist involved in the study of anaphylactic death.</p>
    Formula:C28H28N2O3
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:440.53

    Ref: TM-T14007

  • Methylcarbamyl PAF C-16
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    Methylcarbamyl PAF C-16

    CAS:
    <p>Methylcarbamyl PAF C-16 (Carbamyl-PAF) is a PAF analog with PAF agonistic properties, activating inflammation in pregnancy tissues and promoting preterm birth.</p>
    Formula:C26H55N2O7P
    Color and Shape:Solid
    Molecular weight:538.7

    Ref: TM-T36205

  • 2-Acetylbenzoic acid
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    2-Acetylbenzoic acid

    CAS:
    <p>2-Acetylbenzoic acid outperforms 2-propionyloxybenzoic in hindering platelet function and PG synthesis; both similar in blocking PGI2 creation.</p>
    Formula:C9H8O3
    Purity:99.62%
    Color and Shape:Off-White Solid
    Molecular weight:164.16

    Ref: TM-TMA0536

  • Rocepafant
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    Rocepafant

    CAS:
    <p>Rocepafant (LAU8080), a PAF antagonist, reduces neonatal rat brain damage and inhibits TNF-α toxicity in L929 cells.</p>
    Formula:C26H23ClN6OS2
    Purity:97.31% - 98.95%
    Color and Shape:Solid
    Molecular weight:535.08

    Ref: TM-T28607

  • SDZ-62-434
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    SDZ-62-434

    CAS:
    <p>SDZ-62-434 is a platelet-activating factor inhibitor with antitumor activity and may be used in the study of leukemia.</p>
    Formula:C23H27Cl2N3
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:416.39

    Ref: TM-T28740

  • 48740 RP
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    48740 RP

    CAS:
    <p>48740 RP (RP 55779) is an antagonist of platelet-activating factor.</p>
    Formula:C12H11N3OS
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:245.3

    Ref: TM-T10159

  • Foropafant
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    Foropafant

    CAS:
    <p>Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM).</p>
    Formula:C28H40N4S
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:464.71

    Ref: TM-T15338

  • Apafant
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    Apafant

    CAS:
    <p>Apafant (WEB 2086) is a PAF antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.</p>
    Formula:C22H22ClN5O2S
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:455.96

    Ref: TM-T14300