Cannabinoid Receptor
Cannabinoid receptors are GPCRs that mediate the effects of endogenous cannabinoids (endocannabinoids) and phytocannabinoids, such as those found in cannabis. The two main types of cannabinoid receptors, CB1 and CB2, are involved in regulating a wide range of physiological processes, including pain perception, appetite, mood, and immune function. Cannabinoid receptor modulators have therapeutic potential in treating conditions such as chronic pain, epilepsy, and multiple sclerosis. At CymitQuimica, we offer a wide range of high-quality cannabinoid receptor modulators to support your research in neuropharmacology, pain management, and immunology.
Found 217 products of "Cannabinoid Receptor"
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AM841
CAS:AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.Formula:C26H39NO3SPurity:98%Color and Shape:SolidMolecular weight:445.66Prostaglandin E2-1-glyceryl ester
CAS:Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].Formula:C23H38O7Color and Shape:SolidMolecular weight:426.55PSB-SB1202
CAS:PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].Formula:C23H26O4Color and Shape:SolidMolecular weight:366.45CB2R-IN-1
CAS:CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).Formula:C23H27F3N4O6S3Purity:98%Color and Shape:SolidMolecular weight:608.67CB-25
CAS:CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cellsFormula:C25H41NO3Purity:98%Color and Shape:SolidMolecular weight:403.6CB-52
CAS:CB-52 acts as a neutral antagonist and ligand for the CB2 cannabinoid receptor [1].Formula:C26H43NO3Color and Shape:SolidMolecular weight:417.62OMDM-5
CAS:OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).Formula:C26H44N2O3Purity:99.73%Color and Shape:SolidMolecular weight:432.64Ref: TM-T12306
1mg93.00€5mg177.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,071.00€1mL*10mM (DMSO)210.00€O-Arachidonoyl glycidol
CAS:O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].Formula:C23H36O3Color and Shape:SolidMolecular weight:360.53GSK-554418A
CAS:GSK-554418A, a novel azaindole CB(2) agonists, is used for the treatment of chronic pain. It is efficacious in the acute model and the chronic joint pain model.Formula:C19H19ClN4O2Color and Shape:SolidMolecular weight:370.83CAY10508
CAS:CAY10508 is a potent and selective inverse agonist for the central cannabinoid (CB1) receptor with therapeutic potential for treating obesity and drug dependence, lacking psychotropic effects. It exhibits a Ki value of 243 nM and an EC50 of 195 nM. At a concentration of 10 µM, CAY10508 displaces [3H]-CP-55,940 with 100% efficacy at the CB1 receptor and 35% at the peripheral cannabinoid (CB2) receptor. Its inverse agonist activity at the CB1 receptor was confirmed through a [35S]-GTPγS binding assay.Formula:C21H14Br2N2O2Color and Shape:SolidMolecular weight:486.2GP 1a
CAS:GP 1a: potent CB2 receptor agonist (EC50=7.1), 30x CB2 over CB1 preference, boosts P-ERK1/2, aids skin healing, anti-inflammatory.
Formula:C23H22Cl2N4OPurity:99.79%Color and Shape:SolidMolecular weight:441.35GW 833972A
CAS:GW 833972A: selective CB2 agonist; reduces neural depolarization and citric acid cough in animals.
Formula:C18H14Cl2F3N5OPurity:99.93%Color and Shape:SoildMolecular weight:444.24Bzo-poxizid
CAS:Bzo-poxizid is a synthetic cannabinoid and a psychoactive substance.Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.40BAY 38-7271
CAS:BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).Formula:C20H21F3O5SPurity:98%Color and Shape:SolidMolecular weight:430.44AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Formula:C25H33NO3Color and Shape:SolidMolecular weight:395.53CBR Agonist-2
CBR Agonist-2: CB1 receptor agonist, EC50 - 960 nM, Ki - 970 nM, useful for hCB1R-related disease research.Formula:C27H27FN4OColor and Shape:SolidMolecular weight:442.53PSB-KK1415
CAS:PSB-KK1415 is a selective agonist for the human orphan G protein-coupled receptor GPR18, with an EC50 of 19.1 nM.Formula:C24H23ClN6O2Molecular weight:462.93Cannabigerovarin
CAS:Cannabigerovarin (CBGV) is a compound categorized as a phytocannabinoid.Formula:C19H28O2Molecular weight:288.42Ac-Atovaquone
CAS:Ac-Atovaquone, an ester-acetylated derivative of atovaquone, acts as a potent inhibitor of cytochrome bc1 (cytochrome bc1). This compound shows potential for use in malaria research.Formula:C24H21ClO4Color and Shape:SolidMolecular weight:408.87CBR Agonist-1
CBR Agonist-1 targets CB1R and CB2R with Ki of 0.18 μM and 1.22 μM, useful for studying cannabinoid-related diseases.Formula:C27H27FN4OColor and Shape:SolidMolecular weight:442.53
