Cannabinoid Receptor
Cannabinoid receptors are GPCRs that mediate the effects of endogenous cannabinoids (endocannabinoids) and phytocannabinoids, such as those found in cannabis. The two main types of cannabinoid receptors, CB1 and CB2, are involved in regulating a wide range of physiological processes, including pain perception, appetite, mood, and immune function. Cannabinoid receptor modulators have therapeutic potential in treating conditions such as chronic pain, epilepsy, and multiple sclerosis. At CymitQuimica, we offer a wide range of high-quality cannabinoid receptor modulators to support your research in neuropharmacology, pain management, and immunology.
Found 220 products for "Cannabinoid Receptor".
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SCH-336
CAS:SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.Formula:C23H25NO8S3Purity:97.00%Color and Shape:SolidMolecular weight:539.64Ref: TM-T24771
5mg49.00€1mL*10mM (DMSO)60.00€10mg73.00€25mg152.00€50mg213.00€100mg309.00€200mg444.00€Nonabine
CAS:Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.Formula:C25H33NO2Purity:99.82% - 99.94%Color and Shape:SolidMolecular weight:379.54CB1 agonist 1
CAS:CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.Formula:C24H24N2O5SPurity:98.89%Color and Shape:Yellow SolidMolecular weight:452.52CB2R PAM
CAS:CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.Formula:C21H24BrFN2O2Purity:99.09%Color and Shape:Green SolidMolecular weight:435.33Olorinab
CAS:Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.Formula:C18H23N5O3Purity:97.67% - 98.47%Color and Shape:White SolidMolecular weight:357.412-Linoleoyl Glycerol
CAS:2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.Formula:C21H38O4Color and Shape:SolidMolecular weight:354.531COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Formula:C16H16ClNO3SPurity:99.75%Color and Shape:SolidMolecular weight:337.82Ref: TM-T36520
1mg38.00€5mg86.00€1mL*10mM (DMSO)94.00€10mg123.00€25mg215.00€50mg299.00€100mg411.00€200mg560.00€PF-03550096
CAS:PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1].Formula:C19H28N4O4Color and Shape:SolidMolecular weight:376.45Tedalinab
CAS:Tedalinab is an effective and selective cannabinoid receptor 2 agonist.Formula:C19H21F2N3OPurity:98%Color and Shape:SolidMolecular weight:345.39GSK494581A
CAS:GSK494581A is a GPR55 agonist and glycine transporter subtype 1 inhibitor.Formula:C27H28F2N2O4SPurity:98%Color and Shape:SolidMolecular weight:514.58PF 514273
CAS:PF 514273 is a CB1 receptor antagonist.Formula:C21H17Cl2F2N3O2Purity:98%Color and Shape:SolidMolecular weight:452.28PSNCBAM-1
CAS:PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo.Formula:C22H21ClN4OPurity:99.86%Color and Shape:SolidMolecular weight:392.8811(Z),14(Z)-Eicosadienoic Acid Ethanolamide
CAS:11(Z),14(Z)-Eicosadienoic acid ethanolamide is an ethanolamide derivative of 11(Z),14(Z)-eicosadienoic acid.Formula:C22H41NO2Color and Shape:SolidMolecular weight:351.57SAD-448
CAS:SAD-448 is a cannabinoid receptor type 1 (CB1) agonist. SAD-448 controls spasticity via action on the peripheral nerve CB1 receptor.Formula:C24H28N4O8SColor and Shape:SolidMolecular weight:532.57Prostaglandin E2-1-glyceryl ester
CAS:Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].Formula:C23H38O7Color and Shape:SolidMolecular weight:426.55O-2545 hydrochloride
CAS:O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.Formula:C26H36N2O2HClColor and Shape:SolidMolecular weight:445Tricosanoyl Ethanolamide
CAS:Tricosanoyl ethanolamide, a fatty N-acyl ethanolamine within the endocannabinoid family, has an ethanolamine metabolite whose significance remains to be established.Formula:C25H51NO2Color and Shape:SolidMolecular weight:397.688MCHB-1
CAS:MCHB-1, a potent agonist of the human cannabinoid 2 (CB2) receptor (EC50= 0.52 nM), demonstrates high selectivity for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively), distinguishing itself from similar benzimidazole compounds that significantly alleviate peripheral pain while minimizing central nervous system side effects in mice.Formula:C28H37N3O2Color and Shape:SolidMolecular weight:447.623PSB-SB1202
CAS:PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].Formula:C23H26O4Color and Shape:SolidMolecular weight:366.45CB1 antagonist 1
CAS:CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, andFormula:C26H22Cl2N4Purity:98%Color and Shape:SolidMolecular weight:461.39
