Cannabinoid Receptor
Cannabinoid receptors are GPCRs that mediate the effects of endogenous cannabinoids (endocannabinoids) and phytocannabinoids, such as those found in cannabis. The two main types of cannabinoid receptors, CB1 and CB2, are involved in regulating a wide range of physiological processes, including pain perception, appetite, mood, and immune function. Cannabinoid receptor modulators have therapeutic potential in treating conditions such as chronic pain, epilepsy, and multiple sclerosis. At CymitQuimica, we offer a wide range of high-quality cannabinoid receptor modulators to support your research in neuropharmacology, pain management, and immunology.
Found 223 products for "Cannabinoid Receptor".
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SCH-336
CAS:SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.Formula:C23H25NO8S3Purity:97.00%Color and Shape:SolidMolecular weight:539.64Ref: TM-T24771
5mg49.00€1mL*10mM (DMSO)60.00€10mg73.00€25mg152.00€50mg213.00€100mg309.00€200mg444.00€Nonabine
CAS:Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.Formula:C25H33NO2Purity:99.82% - 99.94%Color and Shape:White SolidMolecular weight:379.54AM-1235
CAS:AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.Formula:C24H21FN2O3Purity:99.92%Color and Shape:Yellow SolidMolecular weight:404.43CB1 agonist 1
CAS:CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.Formula:C24H24N2O5SPurity:98.89%Color and Shape:Yellow SolidMolecular weight:452.52JTE-907
CAS:JTE-907 是一种具有高度选择性和口服活性的 CB2 受体反向激动剂。JTE-907在体内展现出抗炎活性。Formula:C24H26N2O6Purity:99.93%Color and Shape:SolidMolecular weight:438.47Ref: TM-T19705
1mg52.00€5mg119.00€1mL*10mM (DMSO)142.00€10mg177.00€25mg313.00€50mg465.00€100mg662.00€MCHB-1
CAS:MCHB-1, a potent agonist of the human cannabinoid 2 (CB2) receptor (EC50= 0.52 nM), demonstrates high selectivity for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively), distinguishing itself from similar benzimidazole compounds that significantly alleviate peripheral pain while minimizing central nervous system side effects in mice.Formula:C28H37N3O2Color and Shape:SolidMolecular weight:447.623CB-52
CAS:CB-52 acts as a neutral antagonist and ligand for the CB2 cannabinoid receptor [1].Formula:C26H43NO3Color and Shape:SolidMolecular weight:417.62(R)-Monlunabant
CAS:(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].Formula:C26H22ClF3N6O3SPurity:98%Color and Shape:SolidMolecular weight:591CB1 inverse agonist 1
CAS:MRL-650 is an oral, selective CB1 agonist; IC50: CB1=7.5 nM, CB2=4100 nM; anorexigenic effects noted.Formula:C25H18Cl3N3O3Purity:99.92%Color and Shape:SolidMolecular weight:514.79Ref: TM-T10694
1mg50.00€5mg105.00€1mL*10mM (DMSO)129.00€10mg155.00€25mg224.00€50mg314.00€100mg427.00€200mg577.00€Tricosanoyl Ethanolamide
CAS:Tricosanoyl ethanolamide, a fatty N-acyl ethanolamine within the endocannabinoid family, has an ethanolamine metabolite whose significance remains to be established.Formula:C25H51NO2Color and Shape:SolidMolecular weight:397.688AM841
CAS:AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.Formula:C26H39NO3SPurity:98%Color and Shape:SolidMolecular weight:445.66O-2545 hydrochloride
CAS:O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.Formula:C26H36N2O2HClColor and Shape:SolidMolecular weight:445SAD-448
CAS:SAD-448 is a cannabinoid receptor type 1 (CB1) agonist. SAD-448 controls spasticity via action on the peripheral nerve CB1 receptor.Formula:C24H28N4O8SColor and Shape:SolidMolecular weight:532.57URB447
CAS:URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent responses, making it a potential research tool for obesity studies [1].Formula:C25H21ClN2OColor and Shape:SolidMolecular weight:400.9Isopropyl dodec-11-enylfluorophosphonate
CAS:Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibitsFormula:C15H30FO2PPurity:98%Color and Shape:SolidMolecular weight:292.37PSB-SB1202
CAS:PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].Formula:C23H26O4Color and Shape:SolidMolecular weight:366.4511(Z),14(Z)-Eicosadienoic Acid Ethanolamide
CAS:11(Z),14(Z)-Eicosadienoic acid ethanolamide is an ethanolamide derivative of 11(Z),14(Z)-eicosadienoic acid.Formula:C22H41NO2Color and Shape:SolidMolecular weight:351.57Prostaglandin E2-1-glyceryl ester
CAS:Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].Formula:C23H38O7Color and Shape:SolidMolecular weight:426.55PSNCBAM-1
CAS:PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo.Formula:C22H21ClN4OPurity:99.86%Color and Shape:SolidMolecular weight:392.88CB-25
CAS:CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cellsFormula:C25H41NO3Purity:98%Color and Shape:SolidMolecular weight:403.6
