DHFR
Dihydrofolate reductase (DHFR) is an enzyme that plays a crucial role in the folate cycle, which is essential for DNA synthesis, repair, and methylation. DHFR inhibitors are widely used as chemotherapeutic agents in the treatment of cancer and autoimmune diseases due to their ability to inhibit cell proliferation. At CymitQuimica, we provide a variety of DHFR inhibitors to support your research in cancer therapy, immunology, and molecular biology.
Found 34 products for "DHFR".
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Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
Key enzyme in folate metabolism.Color and Shape:Lyophilized PowderMolecular weight:22.0 kDa (predicted)Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
Key enzyme in folate metabolism.Color and Shape:Lyophilized PowderMolecular weight:25.6 kDa (predicted)Dihydrofolate reductase Protein, Human, Recombinant (His)
Key enzyme in folate metabolism.Color and Shape:Lyophilized PowderMolecular weight:25.5 kDa (predicted)QDPR-IN-1
CAS:QDPR-IN-1 (Compound 9b) is an effective inhibitor of QDPR, exhibiting an IC50 value of 0.72 μM.Formula:C12H15N3O2Color and Shape:SolidMolecular weight:233.2664Piritrexim
CAS:Piritrexim (BW 301U) is an orally available fat-soluble dihydrofolate reductase inhibitor with pulmonary toxicity used in the study of uroepithelial carcinomaFormula:C17H19N5O2Purity:99.29% - >99.99%Color and Shape:SolidMolecular weight:325.3651(Rac)-Managlinat dialanetil
CAS:Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.Formula:C21H33N4O6PSPurity:98.52%Color and Shape:SolidMolecular weight:500.55Aditoprime
CAS:Aditoprime (Aditoprim) is a selective bacterial DHFR inhibitor with strong nanomolar potency and broad-spectrum antibacterial activity.Formula:C15H21N5O2Purity:99.89%Color and Shape:White SolidMolecular weight:303.36Clociguanil
CAS:Clociguanil has antimalarial activity.Formula:C12H15Cl2N5OColor and Shape:SolidMolecular weight:316.1910-Deazaaminopterin
CAS:10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.Formula:C20H21N7O5Color and Shape:SolidMolecular weight:439.42DHFR-IN-5
CAS:DHFR-IN-5: potent, oral DHFR inhibitor, Ki 0.54 nM against mutant P. falciparum, anti-malarial.Formula:C18H24N4O4Color and Shape:SolidMolecular weight:360.41Phototrexate
CAS:Phototrexate, a photochromic Methotrexate analog, is a UVA-activated, reversible DHFR inhibitor with antifolate properties (IC50: 6 nM cis vs. 34 μM trans).Formula:C20H19N7O5Color and Shape:SolidMolecular weight:437.41TH9028
CAS:TH9028 inhibits MTHFD1/2/2L, induces replication stress & apoptosis, and shows anti-AML activity.Formula:C16H18N12O5Purity:97.57%Molecular weight:458.39Methotrexate-γ-aspartate
CAS:Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.Formula:C24H27N9O8Purity:98%Color and Shape:SolidMolecular weight:569.53DHFR-IN-4
CAS:DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.Formula:C18H21N5O2SPurity:99.41%Color and Shape:White SolidMolecular weight:371.46
