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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 711 products of "DNA/RNA Synthesis"

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  • TH588 hydrochloride
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    TH588 hydrochloride

    CAS:
    <p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>
    Formula:C13H13Cl3N4
    Color and Shape:Solid
    Molecular weight:331.63

    Ref: TM-T60984

  • SCR7 pyrazine
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    SCR7 pyrazine

    CAS:
    <p>SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).</p>
    Formula:C18H12N4OS
    Purity:98.72% - 99.85%
    Color and Shape:Solid
    Molecular weight:332.38

    Ref: TM-T1724

  • Triazavirin
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    Triazavirin

    CAS:
    <p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>
    Formula:C5H7N6NaO5S
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:286.2

    Ref: TM-T8354

  • CymitQuimica logo
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    CX-5461 dihydrochloride

    <p>CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).</p>
    Formula:C27H29Cl2N7O2S
    Color and Shape:Solid
    Molecular weight:586.54

    Ref: TM-T64150

  • Simeprevir
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    Simeprevir

    CAS:
    <p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>
    Formula:C38H47N5O7S2
    Purity:99.45% - 99.92%
    Color and Shape:Solid
    Molecular weight:749.94

    Ref: TM-T4686

  • Simeprevir sodium
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    Simeprevir sodium

    CAS:
    <p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>
    Formula:C38H46N5NaO7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:771.92

    Ref: TM-T21341

  • Pyridostatin hydrochloride
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    Pyridostatin hydrochloride

    CAS:
    <p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>
    Formula:C31H37Cl5N8O5
    Color and Shape:Solid
    Molecular weight:778.94

    Ref: TM-T72201

  • 1-Hydroxyanthraquinone
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    1-Hydroxyanthraquinone

    CAS:
    <p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>
    Formula:C14H8O3
    Purity:99.56%
    Color and Shape:Orange Red Needles Red-Orange To Fine Yellow Crystals
    Molecular weight:224.21

    Ref: TM-T37101

  • Dasabuvir sodium
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    Dasabuvir sodium

    CAS:
    <p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>
    Formula:C26H26N3NaO5S
    Color and Shape:Solid
    Molecular weight:515.56

    Ref: TM-T63593

  • Idarubicin hydrochloride
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    Idarubicin hydrochloride

    CAS:
    Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).
    Formula:C26H27NO9·HCl
    Purity:98.91% - 99.96%
    Color and Shape:Solid
    Molecular weight:533.95

    Ref: TM-T6010

  • BRD32048
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    BRD32048

    CAS:
    <p>BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.</p>
    Formula:C16H22N6O
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:314.39

    Ref: TM-T23820

  • RI-1
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    RI-1

    CAS:
    RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).
    Formula:C14H11Cl3N2O3
    Purity:99.3% - 99.62%
    Color and Shape:Solid
    Molecular weight:361.61

    Ref: TM-T2276

  • Risdiplam
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    Risdiplam

    CAS:
    <p>Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.</p>
    Formula:C22H23N7O
    Purity:98.68% - 99.64%
    Color and Shape:Solid
    Molecular weight:401.46

    Ref: TM-T16757

  • TH5487
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    TH5487

    CAS:
    <p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>
    Formula:C19H18BrIN4O2
    Purity:98.38% - 98.73%
    Color and Shape:Solid
    Molecular weight:541.18

    Ref: TM-T8119

  • HAMNO
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    HAMNO

    CAS:
    <p>HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).</p>
    Formula:C17H13NO2
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:263.29

    Ref: TM-T4311

  • BMH-21
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    BMH-21

    CAS:
    BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
    Formula:C21H20N4O2
    Purity:99.47% - 99.84%
    Color and Shape:Solid
    Molecular weight:360.41

    Ref: TM-T1767

  • TH287
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    TH287

    CAS:
    <p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>
    Formula:C11H10Cl2N4
    Purity:97.73% - 99%
    Color and Shape:Solid
    Molecular weight:269.13

    Ref: TM-T2069

  • Adenine hydrochloride
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    Adenine hydrochloride

    CAS:
    <p>Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.</p>
    Formula:C5H5N5·HCl
    Purity:98.86%
    Color and Shape:White To Light Yellow Crystal Powder
    Molecular weight:171.59

    Ref: TM-T6225

  • Lurbinectedin
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    Lurbinectedin

    CAS:
    <p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>
    Formula:C41H44N4O10S
    Purity:98.11%
    Color and Shape:Solid
    Molecular weight:784.87

    Ref: TM-T15793

  • FIT-039
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    FIT-039

    CAS:
    <p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>
    Formula:C17H18FN3S
    Purity:98.61%
    Color and Shape:Solid
    Molecular weight:315.41

    Ref: TM-T8972