DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 802 products of "DNA/RNA Synthesis"
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5'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.Formula:C38H47N3O8SiColor and Shape:SolidMolecular weight:701.892EFdA-TP
CAS:EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.Formula:C12H15FN5O12P3Color and Shape:SolidMolecular weight:533.195MRK-952
MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.Formula:C20H20ClF3N6Color and Shape:SolidMolecular weight:436.861Phen-DC3 Trifluoromethanesulfonate
CAS:Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Formula:C36H26F6N6O8S2Purity:98%Color and Shape:SolidMolecular weight:848.75Xanthosine-5'-Triphosphate
CAS:Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.Formula:C10H15N4O15P3Color and Shape:SolidMolecular weight:524.164Guanosine triphosphate
CAS:Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].Formula:C10H16N5O14P3Color and Shape:SolidMolecular weight:523.18Garenoxacin
CAS:Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.Formula:C23H20F2N2O4Purity:98%Color and Shape:SolidMolecular weight:426.415-BrdUTP sodium salt
CAS:5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.Formula:C9H10BrN2Na4O14P3Purity:98%Color and Shape:SolidMolecular weight:634.972'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.Formula:C10H14N5Na2O8PColor and Shape:SolidMolecular weight:409.202Mulnitorsen
CAS:Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].Formula:C172H217N74O82P17S17Color and Shape:SolidMolecular weight:5704.665'-O-DMT-Bz-rC
CAS:5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.Formula:C37H35N3O8Color and Shape:SolidMolecular weight:649.69(+)-Glaucarubinone
(+)-Glaucarubinone is a natural product that can be used as a reference standard.Formula:C25H34O10Color and Shape:SolidMolecular weight:494.537CW-2
CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).Formula:C43H42Cl2FN11O10PtColor and Shape:SolidMolecular weight:1156.21251R-1479
CAS:R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.Formula:C9H12N6O5Purity:98.11% - 99.95%Color and Shape:SolidMolecular weight:284.23Ref: TM-TQ0162
1mg104.00€5mg258.00€10mg358.00€25mg595.00€50mg842.00€100mg1,134.00€200mg1,521.00€1mL*10mM (DMSO)318.00€Bz-rC Phosphoramidite
CAS:Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.Formula:C52H66N5O9PSiColor and Shape:SolidMolecular weight:964.185RNA polymerase II-IN-2
RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.Formula:C41H58N10O12SColor and Shape:SolidMolecular weight:915.025-Methylcytidine 5′-triphosphate
CAS:5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innateFormula:C10H18N3O14P3Color and Shape:SolidMolecular weight:497.18Carbazole
CAS:Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.Formula:C12H9NPurity:99.82%Color and Shape:SolidMolecular weight:167.211KWR137
KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.Formula:C33H31ClF3N9O4Color and Shape:SolidMolecular weight:710.105Cy5-dATP
Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .
Formula:C47H58N7O19P3S2Color and Shape:SolidMolecular weight:1182.05
