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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 707 products of "DNA/RNA Synthesis"

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  • EFdA-TP
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    EFdA-TP

    CAS:
    <p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>
    Formula:C12H15FN5O12P3
    Color and Shape:Solid
    Molecular weight:533.195

    Ref: TM-T41110

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    Ribonuclease T1

    CAS:
    <p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>
    Color and Shape:Solid

    Ref: TM-T73609

  • FF-10502
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    FF-10502

    CAS:
    <p>FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.</p>
    Formula:C9H12FN3O3S
    Color and Shape:Solid
    Molecular weight:261.27

    Ref: TM-T39290

  • 5'-O-TBDMS-dU
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    5'-O-TBDMS-dU

    CAS:
    <p>5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.</p>
    Formula:C15H26N2O5Si
    Color and Shape:Solid
    Molecular weight:342.467

    Ref: TM-T40877

  • RNA splicing modulator 1
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    RNA splicing modulator 1

    CAS:
    <p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>
    Formula:C19H20N6OS
    Color and Shape:Solid
    Molecular weight:380.47

    Ref: TM-T74884

  • EFdA-TP tetraammonium
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    EFdA-TP tetraammonium

    <p>EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.</p>
    Formula:C12H27N9O12P3
    Color and Shape:Solid
    Molecular weight:601.31

    Ref: TM-T35649

  • Clofarabine-5'-diphosphate
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    Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H13ClFN5O9P2
    Color and Shape:Solid
    Molecular weight:463.64

    Ref: TM-T203181

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    13-TP

    <p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>
    Formula:C12H19F2N6O12P3
    Color and Shape:Solid
    Molecular weight:570.23

    Ref: TM-T205409

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    Brr2-IN-2

    <p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>
    Formula:C21H25FN4O2
    Color and Shape:Solid
    Molecular weight:384.45

    Ref: TM-T205260

  • Thailanstatin C
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    Thailanstatin C

    CAS:
    <p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>
    Formula:C30H46ClNO9
    Color and Shape:Solid
    Molecular weight:600.15

    Ref: TM-T38890

  • Ac-rC Phosphoramidite
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    Ac-rC Phosphoramidite

    CAS:
    <p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>
    Formula:C47H64N5O9PSi
    Purity:98.29%
    Color and Shape:Solid
    Molecular weight:902.1

    Ref: TM-T36687

  • 5'-O-DMT-2'-O-TBDMS-Ac-rC
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    5'-O-DMT-2'-O-TBDMS-Ac-rC

    CAS:
    <p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C38H47N3O8Si
    Color and Shape:Solid
    Molecular weight:701.892

    Ref: TM-T37132

  • Garenoxacin
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    Garenoxacin

    CAS:
    <p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>
    Formula:C23H20F2N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.41

    Ref: TM-T7179

  • N2-Acetylguanine
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    N2-Acetylguanine

    CAS:
    <p>Compound 19962-37-9, with CAS No. 19962-37-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 19962-37-9 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C7H7N5O2
    Purity:99.90%
    Color and Shape:White Solid
    Molecular weight:193.166

    Ref: TM-TPL0270

  • Bromochloroacetonitrile
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    Bromochloroacetonitrile

    CAS:
    <p>Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.</p>
    Formula:C2HBrClN
    Color and Shape:Solid
    Molecular weight:154.39

    Ref: TM-T40933

  • 7-TFA-ap-7-Deaza-ddG
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    7-TFA-ap-7-Deaza-ddG

    CAS:
    <p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>
    Formula:C16H16F3N5O4
    Color and Shape:Solid
    Molecular weight:399.33

    Ref: TM-T38531

  • 5'-O-TBDMS-dA
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    5'-O-TBDMS-dA

    CAS:
    <p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C16H27N5O3Si
    Color and Shape:Solid
    Molecular weight:365.509

    Ref: TM-T37143

  • 5'-O-DMT-ibu-dC
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    5'-O-DMT-ibu-dC

    CAS:
    <p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>
    Formula:C34H37N3O7
    Color and Shape:Solid
    Molecular weight:599.67

    Ref: TM-T38405

  • Nusinersen
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    Nusinersen

    CAS:
    <p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>
    Purity:98.62%
    Color and Shape:Solid

    Ref: TM-T38656

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    DG1

    <p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>
    Formula:C19H17N5O5S
    Color and Shape:Solid
    Molecular weight:427.43

    Ref: TM-T78751