DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 730 products for "DNA/RNA Synthesis".
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Dasabuvir sodium
CAS:Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).Formula:C26H26N3NaO5SColor and Shape:SolidMolecular weight:515.56PCNA-I1
CAS:PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.Formula:C17H14N2O2SPurity:97.64%Color and Shape:SolidMolecular weight:310.37Quarfloxin
CAS:Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.Formula:C35H33FN6O3Purity:99.77%Color and Shape:SolidMolecular weight:604.67Ref: TM-T16703
1mg71.00€2mg92.00€5mg152.00€1mL*10mM (DMSO)212.00€10mg236.00€25mg380.00€50mg530.00€100mg708.00€SR18662
CAS:SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.Formula:C16H19Cl2N3O4SPurity:98.97% - 99.38%Color and Shape:White SolidMolecular weight:420.31Ref: TM-T22429
200mgTo inquire2mg39.00€5mg60.00€1mL*10mM (DMSO)60.00€10mg92.00€25mg177.00€50mg285.00€100mg408.00€Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:Yellow SolidMolecular weight:938.71CB-6644
CAS:CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.Formula:C29H34ClFN4O5Purity:96.33% - 99.78%Color and Shape:SolidMolecular weight:573.06Ref: TM-T10693
1mg205.00€5mg416.00€1mL*10mM (DMSO)525.00€10mg533.00€25mg748.00€50mg973.00€100mg1,260.00€5-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Formula:C9H11BrN2O6Purity:99.89%Color and Shape:White PowderMolecular weight:323.1PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurity:99.19%Color and Shape:White SolidMolecular weight:453.9Ref: TM-T84770
1mg84.00€5mg170.00€1mL*10mM (DMSO)195.00€10mg281.00€25mg542.00€50mg757.00€100mg1,044.00€GSK4418959
CAS:GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.Formula:C31H30F4N4O5SPurity:99.14%Color and Shape:White SolidMolecular weight:646.65DHX9-IN-8
CAS:DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].Formula:C18H16N2O3S2Color and Shape:SolidMolecular weight:372.46VVD-214
CAS:VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Formula:C20H21F2N3O4SPurity:99.24% - 99.93%Color and Shape:White SolidMolecular weight:437.46Ref: TM-T85309
1mg69.00€5mg147.00€1mL*10mM (DMSO)164.00€10mg224.00€25mg358.00€50mg512.00€100mg707.00€Metribuzin
CAS:Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.Formula:C8H14N4OSPurity:99.07%Color and Shape:SolidMolecular weight:214.29Cytarabine 5′-monophosphate
CAS:Cytarabine 5′-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase α, significantly slowing DNA synthesis. It inhibits nuclear and mitochondrial DNA replication in S. cerevisiae at 15 mM and improves survival in an L1210 murine leukemia model at 3.5-75.1 mg/kg.Formula:C9H14N3O8PColor and Shape:SolidMolecular weight:323.198Cytidine 3'-monophosphate
CAS:Cytidine 3'-monophosphate, a ribonucleotide, results from the hydrolysis of cytidine 2',3'-cyclic monophosphate via RNase—a process that cytidine 3'-monophosphate itself inhibits. Additionally, it can be dephosphorylated to cytidine by 3'-nucleotidase.Formula:C9H14N3O8PColor and Shape:SolidMolecular weight:323.2AB25583
CAS:AB25583 is a Polθ helicase inhibitor; blocks MMEJ repair; shows synthetic lethality in BRCA-deficient cells; DNA repair research.Formula:C22H17ClN4O3SPurity:99.21%Color and Shape:White SolidMolecular weight:452.91RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formula:C19H17N3Color and Shape:SolidMolecular weight:287.36E-982
CAS:E-982 is derived from the reference compound.Formula:C25H31NO6SPurity:98%Color and Shape:SolidMolecular weight:473.58Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formula:C16H17BrClN3O3Purity:99.53%Color and Shape:Yellow SolidMolecular weight:414.68Ref: TM-T6856
1mg34.00€5mg82.00€1mL*10mM (DMSO)92.00€10mg116.00€25mg227.00€50mg344.00€100mg517.00€500mg1,134.00€3,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formula:C7H10BrNO2Purity:98.49%Color and Shape:SolidMolecular weight:220.06E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46
