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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 706 products of "DNA/RNA Synthesis"

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  • CB 30900
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    CB 30900

    CAS:
    <p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>
    Formula:C31H32FN5O9
    Color and Shape:Solid
    Molecular weight:637.61

    Ref: TM-T30760

  • DENV-IN-6
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    DENV-IN-6

    CAS:
    <p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>
    Formula:C23H26ClFN4OS
    Color and Shape:Solid
    Molecular weight:461

    Ref: TM-T62908

  • APE1-IN-3
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    APE1-IN-3

    CAS:
    <p>APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.</p>
    Formula:C17H16O4
    Color and Shape:Solid
    Molecular weight:284.31

    Ref: TM-T89919

  • GTSE1-IN-1
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    GTSE1-IN-1

    CAS:
    <p>GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.</p>
    Formula:C21H24FN7
    Color and Shape:Solid
    Molecular weight:393.46

    Ref: TM-T200127

  • WRN inhibitor 11
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    WRN inhibitor 11

    CAS:
    <p>WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.</p>
    Formula:C34H35ClF3N9O5
    Color and Shape:Solid
    Molecular weight:742.15

    Ref: TM-T201262

  • 2-CEES
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    2-CEES

    CAS:
    <p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>
    Formula:C4H9ClS
    Color and Shape:Solid
    Molecular weight:124.632

    Ref: TM-T204286

  • D-G23
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    D-G23

    CAS:
    <p>D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.</p>
    Formula:C19H22N4O3
    Color and Shape:Solid
    Molecular weight:354.403

    Ref: TM-T206763

  • MTH1 activator-1
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    MTH1 activator-1

    CAS:
    <p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>
    Formula:C29H23F3N4O2
    Color and Shape:Solid
    Molecular weight:516.514

    Ref: TM-T204503

  • NRTT-IN-1
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    NRTT-IN-1

    CAS:
    <p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>
    Formula:C28H24FN5O5
    Color and Shape:Solid
    Molecular weight:529.519

    Ref: TM-T205482

  • 12(S)-HETE
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    12(S)-HETE

    CAS:
    <p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>
    Formula:C20H32O3
    Color and Shape:Solid
    Molecular weight:320.47

    Ref: TM-T37047

  • Polθ-IN-5
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    Polθ-IN-5

    CAS:
    <p>Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.</p>
    Formula:C23H18ClF2N7O3S
    Color and Shape:Solid
    Molecular weight:545.95

    Ref: TM-T200913

  • Werner syndrome RecQ helicase-IN-2
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    Werner syndrome RecQ helicase-IN-2

    CAS:
    <p>Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.</p>
    Formula:C32H34F3N9O5
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:681.67

    Ref: TM-T72108

  • WRN inhibitor 12
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    WRN inhibitor 12

    CAS:
    <p>WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.</p>
    Formula:C33H33ClF3N9O5
    Color and Shape:Solid
    Molecular weight:728.12

    Ref: TM-T201316

  • Uridine 3',5'-diphosphate
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    Uridine 3',5'-diphosphate

    CAS:
    <p>Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].</p>
    Formula:C9H14N2O12P2
    Color and Shape:Solid
    Molecular weight:404.16

    Ref: TM-T87599

  • Bersiporocin
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    Bersiporocin

    CAS:
    <p>Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.</p>
    Formula:C15H19Cl2N3O
    Purity:98.88% - 99.79%
    Color and Shape:Solid
    Molecular weight:328.24

    Ref: TM-T39739

  • ATIC-IN-2
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    ATIC-IN-2

    CAS:
    <p>ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), binding to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM.</p>
    Formula:C4H4N4O3S
    Color and Shape:Solid
    Molecular weight:188.165

    Ref: TM-T204433

  • Polθ-IN-6
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    Polθ-IN-6

    CAS:
    <p>Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.</p>
    Formula:C25H23N3O3S
    Color and Shape:Solid
    Molecular weight:445.53

    Ref: TM-T200918

  • GSK_WRN4
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    GSK_WRN4

    CAS:
    <p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>
    Formula:C16H20N2O4S
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:336.41

    Ref: TM-T200332

  • AB25583
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    AB25583

    CAS:
    <p>AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.</p>
    Formula:C22H17ClN4O3S
    Color and Shape:Solid
    Molecular weight:452.91

    Ref: TM-T200101

  • 2'-(2-Nitrobenzyl)-ATP
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    2'-(2-Nitrobenzyl)-ATP

    CAS:
    <p>2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.</p>
    Formula:C17H21N6O15P3
    Color and Shape:Solid
    Molecular weight:642.30

    Ref: TM-T207643