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HIV Protease

HIV Protease

HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.

Found 447 products of "HIV Protease"

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  • Methyl piperazine-2-carboxylate

    CAS:
    <p>Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.</p>
    Formula:C6H12N2O2
    Color and Shape:Solid
    Molecular weight:144.172
  • BI-2540

    CAS:
    <p>BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .</p>
    Formula:C24H15ClF5NO5
    Color and Shape:Solid
    Molecular weight:527.83
  • Desthiazolylmethyl ritonavir

    CAS:
    <p>Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.</p>
    Formula:C33H43N5O4S
    Color and Shape:Solid
    Molecular weight:605.791
  • HIV-1 protease-IN-6


    <p>HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.</p>
    Formula:C27H31FN2O6S
    Color and Shape:Solid
    Molecular weight:530.61
  • NBD-14189

    CAS:
    <p>NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 &lt;200 nM).</p>
    Formula:C18H16F4N4O2S
    Color and Shape:Solid
    Molecular weight:428.40
  • BI 224436

    CAS:
    <p>BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.</p>
    Formula:C27H26N2O4
    Color and Shape:Solid
    Molecular weight:442.51
  • BRD-K98645985

    CAS:
    <p>BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.</p>
    Formula:C33H43N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:573.73
  • PD 134922

    CAS:
    <p>PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.</p>
    Formula:C37H61N5O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:719.97
  • MIV-150

    CAS:
    <p>MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50&lt;1 nM against HIV-1/HIV-2MN).</p>
    Formula:C19H17FN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.36
  • ZK-316

    CAS:
    <p>ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.</p>
    Formula:C27H22D6N6O3S2
    Color and Shape:Solid
    Molecular weight:554.72
  • BMIM-TFSI

    CAS:
    <p>BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.</p>
    Formula:C10H15F6N3O4S2
    Color and Shape:Solid
    Molecular weight:419.364
  • HIV-1 inhibitor-44


    <p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>
    Formula:C23H26N2O4S
    Color and Shape:Solid
    Molecular weight:426.53
  • A 76889

    CAS:
    <p>A 76889 is an inhibitor of HIV-1 protease.</p>
    Formula:C44H58N8O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:794.98
  • BRN3OMe

    CAS:
    <p>BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.</p>
    Formula:C7H13N3O4
    Color and Shape:Solid
    Molecular weight:203.196
  • Telinavir

    CAS:
    <p>Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.</p>
    Formula:C33H44N6O5
    Color and Shape:Solid
    Molecular weight:604.74
  • GSK3739936

    CAS:
    <p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 &gt;24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>
    Formula:C34H43FN2O4
    Color and Shape:Solid
    Molecular weight:562.71
  • HIV-1 inhibitor-40


    <p>HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.</p>
    Formula:C25H18N6O2
    Color and Shape:Solid
    Molecular weight:434.45
  • Lentiginosine

    CAS:
    <p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>
    Formula:C8H15NO2
    Color and Shape:Solid
    Molecular weight:157.21
  • L-697639

    CAS:
    <p>L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.</p>
    Formula:C18H21N3O2
    Color and Shape:Solid
    Molecular weight:311.38
  • GS-9822

    CAS:
    <p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>
    Formula:C36H39ClN4O4S
    Color and Shape:Solid
    Molecular weight:659.24