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HIV Protease

HIV Protease

HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.

Found 477 products of "HIV Protease"

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  • NBD-10007

    CAS:
    NBD-10007 is an inhibitor of HIV-1 entry.
    Formula:C20H25ClN4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.96
  • Integrase-LEDGF/p75 allosteric inhibitor 1

    CAS:
    Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).
    Formula:C33H41NO6S
    Color and Shape:Solid
    Molecular weight:579.75
  • L-697639

    CAS:
    L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.
    Formula:C18H21N3O2
    Color and Shape:Solid
    Molecular weight:311.38
  • HIV-1 inhibitor-18


    <p>HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50&gt;9.51).</p>
    Formula:C27H31N3O6S
    Color and Shape:Solid
    Molecular weight:525.62
  • (S)-Batylalcohol

    CAS:
    <p>(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.</p>
    Formula:C21H44O3
    Color and Shape:Solid
    Molecular weight:344.572
  • NBD-14189

    CAS:
    NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).
    Formula:C18H16F4N4O2S
    Color and Shape:Solid
    Molecular weight:428.40
  • Fipravirimat

    CAS:
    Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.
    Formula:C43H67FN2O4S
    Color and Shape:Solid
    Molecular weight:727.07
  • BI-2540

    CAS:
    <p>BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .</p>
    Formula:C24H15ClF5NO5
    Color and Shape:Solid
    Molecular weight:527.83
  • BRD-K98645985

    CAS:
    BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.
    Formula:C33H43N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:573.73
  • ZK-316

    CAS:
    ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.
    Formula:C27H22D6N6O3S2
    Color and Shape:Solid
    Molecular weight:554.72
  • BMIM-TFSI

    CAS:
    <p>BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.</p>
    Formula:C10H15F6N3O4S2
    Color and Shape:Solid
    Molecular weight:419.364
  • HIV-1 inhibitor-40


    HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.
    Formula:C25H18N6O2
    Color and Shape:Solid
    Molecular weight:434.45
  • 4'-Ethynyl-2'-deoxyadenosine

    CAS:
    4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).
    Formula:C12H13N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:275.26
  • Gardiquimod hydrochloride

    CAS:
    Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.
    Formula:C17H24ClN5O
    Color and Shape:Solid
    Molecular weight:349.858
  • DPC 684

    CAS:
    DPC 684 is a potent and selective HIV-1 protease inhibitor with an IC90 of 5.7-40 nM and a Ki of 0.021 nM. It competitively inhibits HIV-1 protease, preventing viral polyprotein cleavage. Compared to cellular proteases, DPC 684 shows high selectivity for retroviral proteases. The compound exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant HIV-1 proteases, with an IC90 of 1.9-6.3 nM. DPC 684 is significant for HIV research.
    Formula:C35H48FN5O5S
    Color and Shape:Solid
    Molecular weight:669.85
  • Desthiazolylmethyl ritonavir

    CAS:
    <p>Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.</p>
    Formula:C33H43N5O4S
    Color and Shape:Solid
    Molecular weight:605.791
  • HIV-1-IN-86

    CAS:
    HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.
    Formula:C20H17N3O7S
    Color and Shape:Solid
    Molecular weight:443.43
  • HIV-IN-3


    <p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>
    Formula:C21H32ClN7O3
    Color and Shape:Solid
    Molecular weight:465.98
  • ATPase-IN-6

    CAS:
    ATPase-IN-6 is an inhibitor of H+/K+-ATPase (ATPase) and a derivative of imidazopyridine. It exhibits significant antiviral activity against various viruses, such as HIV-1 and SARS-CoV-2. ATPase-IN-6 is applicable in antiviral infection research.
    Formula:C29H25N3O4S
    Color and Shape:Solid
    Molecular weight:511.59
  • A 76889

    CAS:
    A 76889 is an inhibitor of HIV-1 protease.
    Formula:C44H58N8O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:794.98
  • L 702007

    CAS:
    <p>L 702007 is an inhibitor of HIV-1 reverse transcriptase.</p>
    Formula:C18H25N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:315.41
  • BI 224436

    CAS:
    BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.
    Formula:C27H26N2O4
    Color and Shape:Solid
    Molecular weight:442.51
  • BMS-378806


    <p>BMS-378806 is an HIV inhibitor with EC50: 0.85-26.5nM for various strains.</p>
    Formula:C22H22N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.43

    Ref: TM-T22609

    1mg
    Discontinued
    2mg
    Discontinued
    Discontinued product
  • Aurothioglucose

    CAS:
    Aurothioglucose is a active-site TrxR1 inhibitor.
    Formula:C6H11AuO5S
    Purity:98%
    Color and Shape:Yellow Crystals Solid
    Molecular weight:392.18

    Ref: TM-T14351

    100mg
    Discontinued
    Discontinued product
  • 3-Deazaadenosine

    CAS:
    3-Deazaadenosine, an inhibitor of S-adenosylhomocysteine hydrolase with a Ki of 3.9 μM, exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.
    Formula:C11H14N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:266.25

    Ref: TM-T10111L

    5mg
    Discontinued
    Discontinued product
  • Oxindole

    CAS:
    <p>Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.</p>
    Formula:C8H7NO
    Purity:99.34%
    Color and Shape:Off-White Crystalline Powder
    Molecular weight:133.15

    Ref: TM-FR16741

    1g
    Discontinued
    5g
    Discontinued
    10g
    Discontinued
    Discontinued product
  • HIV-1 integrase inhibitor

    CAS:
    Hiv-1 integrase inhibitor is an effective anti-HIV drug.
    Formula:C11H9N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:247.21

    Ref: TM-T11566

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product