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HIV Protease

HIV Protease

HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.

Found 447 products of "HIV Protease"

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  • SPD-756

    CAS:
    <p>SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>
    Formula:C12H16N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:292.29
  • NNRT-IN-6


    <p>NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.</p>
    Formula:C32H31N9O3S
    Color and Shape:Solid
    Molecular weight:621.71
  • Aureothin

    CAS:
    <p>Aureothin: a nitroaryl polyketide with antitumor, antifungal &amp; insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).</p>
    Formula:C22H23NO6
    Color and Shape:Solid
    Molecular weight:397.42
  • HIV-1 inhibitor-80


    <p>HIV-1inhibitor-80 (compound M44) is an HIV-1 inhibitor with an EC50 of 5-148 nM. It demonstrates excellent metabolic stability and low cytotoxicity in human plasma and liver microsomes.</p>
    Formula:C26H19N7O
    Color and Shape:Solid
    Molecular weight:445.475
  • Bictegravir Sodium

    CAS:
    <p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>
    Formula:C21H17F3N3NaO5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:471.36
  • CI-39

    CAS:
    <p>CI-39, an NNRTI with EC50 of 3.40 µM, inhibits HIV-1 reverse transcriptase and RNase H, with CC50 &gt;30 µM.</p>
    Formula:C19H18N2O4
    Color and Shape:Solid
    Molecular weight:338.36
  • Indoline

    CAS:
    <p>Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C8H9N
    Color and Shape:Clear To Yellow Liquid
    Molecular weight:119.16
  • (-)-Rabdosiin

    CAS:
    <p>(-)-Rabdosiin, identified as a novel phenolic marker in Symphytum officinale L., exhibits antioxidant, neuroprotective, and anti-HIV activities [1].</p>
    Formula:C36H30O16
    Color and Shape:Solid
    Molecular weight:718.61
  • HIV-1 protease-IN-14


    <p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>
    Color and Shape:Odour Solid
  • HIV-IN-2

    CAS:
    <p>HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1].</p>
    Formula:C34H27ClF7N9O3S
    Color and Shape:Solid
    Molecular weight:810.14
  • 4-Deoxy-4α-phorbol

    CAS:
    <p>4-Deoxy-4α-phorbol, a tetracyclic diterpene identified in E.</p>
    Formula:C20H28O5
    Color and Shape:Solid
    Molecular weight:348.43
  • JE-2178

    CAS:
    <p>JE-2178 is compound with high bioavailability .</p>
    Formula:C35H51N5O6S
    Color and Shape:Solid
    Molecular weight:669.87
  • Hinnuliquinone

    CAS:
    <p>Hinnuliquinone is an anti-HIV agent.</p>
    Formula:C32H30N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.59
  • ICeD-2


    <p>ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.</p>
    Formula:C20H29N3O
    Color and Shape:Solid
    Molecular weight:327.46
  • Elvucitabine

    CAS:
    <p>Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.</p>
    Formula:C9H10FN3O3
    Color and Shape:Solid
    Molecular weight:227.19
  • Clavirolide L


    <p>Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without</p>
    Formula:C20H28O3
    Color and Shape:Solid
    Molecular weight:316.43
  • RPR103611

    CAS:
    <p>RPR103611, a betulinic acid derivative, inhibits HIV-1; IC50s: CCR5 (YU2) 80, CXCR4 (NL4-3) 0.27, dual-tropic (89.6) 0.17.</p>
    Formula:C46H78N2O6
    Color and Shape:Solid
    Molecular weight:755.12
  • Decanoyl-RVKR-CMK TFA

    CAS:
    <p>Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.</p>
    Formula:C36H67ClF3N11O7
    Color and Shape:Solid
    Molecular weight:858.45
  • Emtricitabine S-oxide

    CAS:
    <p>Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.</p>
    Formula:C8H10FN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:263.25
  • (+)-Carbovir triphosphate

    CAS:
    <p>(+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.</p>
    Formula:C11H16N5O11P3
    Color and Shape:Solid
    Molecular weight:487.19
  • TAT peptide


    <p>TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.</p>
    Formula:C65H124N34O15
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1621.91
  • HIV-1 protease-IN-4


    <p>HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC &amp; 67x C24 compared to atazanavir.</p>
    Formula:C48H69N7O11
    Color and Shape:Solid
    Molecular weight:920.1
  • JE-2147

    CAS:
    <p>JE-2147: a hybrid peptide with multiple amino acid types linked by peptide bonds.</p>
    Formula:C32H37N3O5S
    Color and Shape:Solid
    Molecular weight:575.72
  • GLR-19

    CAS:
    <p>GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].</p>
    Formula:C102H194N40O20
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2300.89
  • HIV-1 protease-IN-10


    <p>HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) and</p>
    Formula:C23H40O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:396.56
  • Alvircept sudotox

    CAS:
    <p>Alvircept sudotox, a recombinant CD4 fused with exotoxin A from Pneumonas aeruginosa, is utilized in HIV infection research [1].</p>
    Color and Shape:Liquid
  • Carbovir triphosphate

    CAS:
    <p>Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].</p>
    Formula:C11H16N5O11P3
    Color and Shape:Solid
    Molecular weight:487.19
  • Kni 102

    CAS:
    <p>Kni 102 is a biochemical.</p>
    Formula:C31H41N5O7
    Color and Shape:Solid
    Molecular weight:595.69
  • Lopinavir Metabolite M-1

    CAS:
    <p>Lopinavir Metabolite M-1, derived from Lopinavir, inhibits HIV protease (Ki=0.7 pM) and shows antiviral activity in vitro.</p>
    Formula:C37H46N4O6
    Color and Shape:Solid
    Molecular weight:642.78
  • Scirpusin A

    CAS:
    <p>Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.</p>
    Formula:C28H22O7
    Color and Shape:Solid
    Molecular weight:470.47
  • NF279

    CAS:
    <p>P2X1 antagonist</p>
    Formula:C49H36N6Na6O23S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1407.17
  • HIV-1 inhibitor-59


    <p>HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.</p>
    Formula:C28H28FN5O3S
    Color and Shape:Solid
    Molecular weight:533.62
  • QYL-685

    CAS:
    <p>QYL-685 is a methylenecyclopropane nucleoside analog.</p>
    Formula:C20H24N7O5P
    Color and Shape:Solid
    Molecular weight:473.42
  • Delavirdine

    CAS:
    <p>Delavirdine, an NNRTI for HIV-1, is used in HAART.</p>
    Formula:C22H28N6O3S
    Color and Shape:Solid
    Molecular weight:456.56
  • Hypoglaunine D

    CAS:
    <p>Hypoglaunine D, an anti-HIV analogue of Triptonine B, inhibits HIV in H9 cells with an EC50 of 22 μg/ml.</p>
    Formula:C41H47NO19
    Color and Shape:Solid
    Molecular weight:857.81
  • HIV-IN-9


    <p>HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.</p>
    Color and Shape:Odour Solid
  • Kadsuralignan A

    CAS:
    <p>Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an</p>
    Formula:C22H26O7
    Color and Shape:Solid
    Molecular weight:402.44
  • MB-66


    <p>MB-66 (MAPP-66) is a fully human IgG1 antibody targeting HSV and HIV. It is a monoclonal antibody membrane intended for vaginal application. The isotype control for MB-66 can be referred to as HumanIgG1kappa, Isotype Control.</p>
    Color and Shape:Odour Liquid
  • Cys-TAT(47-57)

    CAS:
    <p>Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.</p>
    Formula:C67H124N34O14S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1661.99
  • HIV-1 inhibitor-58


    <p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>
    Formula:C26H24N6O2
    Color and Shape:Solid
    Molecular weight:452.51
  • 12-Oxocalanolide A


    <p>12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.</p>
    Formula:C22H24O5
    Color and Shape:Solid
    Molecular weight:368.429
  • Salvianan A

    CAS:
    <p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>
    Formula:C20H17NO2
    Color and Shape:Solid
    Molecular weight:303.35
  • Amdoxovir

    CAS:
    <p>Amdoxovir is a reverse transcriptase inhibitor.</p>
    Formula:C9H12N6O3
    Color and Shape:Solid
    Molecular weight:252.23
  • HIV gag peptide (197-205)

    CAS:
    <p>HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI</p>
    Formula:C45H81N11O14S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1064.32
  • MPG, HIV related

    CAS:
    <p>MPG: 27-amino acid peptide from HIV-1 gp41 &amp; SV40 T antigen, delivers nucleic acids into cells efficiently.</p>
    Formula:C126H201N35O33S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2766.22
  • Kuguacin N


    <p>Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.</p>
    Formula:C30H46O4
    Color and Shape:Solid
    Molecular weight:470.694
  • Peptide T TFA

    CAS:
    <p>Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.</p>
    Formula:C37H56F3N9O18
    Purity:98%
    Color and Shape:Solid
    Molecular weight:971.89
  • Peptide T

    CAS:
    <p>Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.</p>
    Formula:C35H55N9O16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:857.86
  • HIV-1 inhibitor-81


    <p>HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.</p>
    Formula:C32H44N2O8S
    Color and Shape:Solid
    Molecular weight:616.77
  • Globotriaosylceramides (porcine)

    CAS:
    <p>Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.</p>
    Formula:C60H113NO18
    Color and Shape:Solid
    Molecular weight:1136.553