HIV Protease
HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.
Found 473 products for "HIV Protease".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
ICeD-2
ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.Formula:C20H29N3OColor and Shape:SolidMolecular weight:327.46Pol (476-484), HIV-1 RT Epitope
CAS:Pol (476-484), HIV-1 RT Epitope is a biologically active peptide and represents the dominant HLA A*0201-restricted epitope within HIV-1 reverse transcriptase (Formula:C46H78N12O12Color and Shape:SolidMolecular weight:991.18HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.Formula:C42H36ClF10N7O5S2Color and Shape:SolidMolecular weight:1008.35Peptide T TFA
CAS:Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.Formula:C37H56F3N9O18Purity:98%Color and Shape:SolidMolecular weight:971.89BMS-955176 TFA
CAS:GSK3532795: Oral HIV-1 maturation inhibitor, broad virus coverage, EC50: 15 nM, good preclinical pharmacokinetics.Formula:C44H64N2O8SPurity:98%Color and Shape:SolidMolecular weight:781.06Peptide T
CAS:Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.Formula:C35H55N9O16Purity:98%Color and Shape:SolidMolecular weight:857.86SPD-756
CAS:SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C12H16N6O3Purity:98%Color and Shape:SolidMolecular weight:292.29NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Formula:C32H31N9O3SColor and Shape:SolidMolecular weight:621.71HIV-1 protease-IN-4
HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC & 67x C24 compared to atazanavir.Formula:C48H69N7O11Color and Shape:SolidMolecular weight:920.1Lopinavir Metabolite M-1
CAS:Lopinavir Metabolite M-1, derived from Lopinavir, inhibits HIV protease (Ki=0.7 pM) and shows antiviral activity in vitro.Formula:C37H46N4O6Color and Shape:SolidMolecular weight:642.78Tipranavir
CAS:Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzymeFormula:C31H33F3N2O5SPurity:99.85%Color and Shape:White SolidMolecular weight:602.66Ref: TM-T4578
1mg69.00€5mg147.00€1mL*10mM (DMSO)192.00€10mg260.00€25mg580.00€50mg888.00€100mg1,485.00€200mg2,008.00€(+)-Carbovir triphosphate
CAS:(+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.Formula:C11H16N5O11P3Color and Shape:SolidMolecular weight:487.19PROTAC Vif degrader-1
PROTACVif degrader-1 (Compound L15) is a Vif-targeted PROTAC degrader exhibiting anti-HIV-1 virucidal activity, with an EC50 of 33.35 μM against HIV-1IIIB.Color and Shape:Odour SolidGLR-19
CAS:GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Formula:C102H194N40O20Purity:98%Color and Shape:SolidMolecular weight:2300.89UK-88947 HCl
CAS:UK 88947 is a protease inhibitor.Formula:C41H63ClN6O6Purity:98%Color and Shape:SolidMolecular weight:771.44HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Color and Shape:Odour SolidN36Mut(e,g)
N36Mut(e,g) is an HIV fusion peptide inhibitor targeting gp41. It functions by disrupting the formation of the homotrimeric coiled coil of the N-terminal helix in the pre-hairpin intermediate, leading to the creation of a heterotrimer.Formula:C189H317N55O56Color and Shape:SolidMolecular weight:4255.87Decanoyl-RVKR-CMK
CAS:Inhibits all seven proprotein convertases; stops proET-1 processing; hinders VGF secretion in PC12 cells.Formula:C34H66ClN11O5Purity:98%Color and Shape:SolidMolecular weight:744.42HIV Protease Substrate 1 TFA
HIV Protease Substrate 1 TFA, a fluorogenic substrate for HIV protease, facilitates the investigation of the enzyme's activity [1].Formula:C94H134F3N27O25SColor and Shape:SolidMolecular weight:2131.29AL-470
CAS:AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFormula:C67H57N7O23Color and Shape:SolidMolecular weight:1328.2L 754394
CAS:L 754394 is an effective and specific inhibitor of the HIV-1 protease.Formula:C38H47N5O5Color and Shape:SolidMolecular weight:653.81HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFormula:C23H40O5Purity:98%Color and Shape:SolidMolecular weight:396.56Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Color and Shape:Odour SolidRef: TM-L1100
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireTAT peptide
TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.Formula:C65H124N34O15Purity:98%Color and Shape:SolidMolecular weight:1621.91Antitumor agent-191
Antitumor agent-191 (Compound 7) exhibits antiviral activity against HSV-1 and HIV, with EC50 values of 0.03 μM and 0.81 μM, respectively. It also demonstrates potential antitumor properties by inhibiting cancer cell lines HepG2, WI-38, Vero, and MCF-7, with IC50 values of 19.6, 39.3, 18.3, and 28 μM, respectively.Formula:C22H14N12S2Color and Shape:SolidMolecular weight:510.557VRC01LS
VRC01LS is a humanized monoclonal antibody inhibitor that targets the CD4 binding site of the HIV-1 envelope glycoprotein (Env). By blocking the interaction between HIV-1 and the host cell's CD4 receptor, VRC01LS inhibits viral entry. It holds potential for research in HIV-1 infection.Color and Shape:Odour LiquidDecanoyl-RVKR-CMK TFA
CAS:Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.Formula:C36H67ClF3N11O7Color and Shape:SolidMolecular weight:858.45GRL-07524
GRL-07524 (Compound 4e) is a potent HIV-1 protease inhibitor with a Ki of 0.22 nM. It contains an oxaspirocarbamate as the P2 ligand and demonstrates strong antiviral activity, with an EC50 of 210 nM. GRL-07524 can bind to the active site of HIV-1PR and crucial catalytic residues, interacting with one of four symmetric-independent molecules.Color and Shape:Odour SolidVIR-165
VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.Formula:C109H158N22O25S2Purity:98%Color and Shape:SolidMolecular weight:2240.7Bictegravir Sodium
CAS:Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Formula:C21H17F3N3NaO5Purity:99.97%Color and Shape:SolidMolecular weight:471.36MPG, HIV related
CAS:MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Formula:C126H201N35O33SPurity:98%Color and Shape:SolidMolecular weight:2766.22HIV-1 inhibitor-59
HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.Formula:C28H28FN5O3SColor and Shape:SolidMolecular weight:533.62HIV-1-IN-83
HIV-1-IN-83 (Compound 18E) is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1. It demonstrates an IC50 of 0.45 μM against wild-type HIV-1 reverse transcriptase. HIV-1-IN-83 exhibits potent antiviral activity against both wild-type and mutant HIV-1 strains and enhances drug resistance in Y188L and RES056 mutants. The compound is non-toxic up to a concentration of 11.088 μM.Color and Shape:Odour SolidHIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Color and Shape:Odour SolidAureothin
CAS:Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).Formula:C22H23NO6Color and Shape:SolidMolecular weight:397.42HIV-1 inhibitor-79
HIV-1inhibitor-79 (Compound 3k) is an HIV inhibitor that demonstrates significant inhibitory activity against HIV-1 and its common mutants, with IC50 values of 1.9 nM for HIV-1, K103, 8.7 nM for L100I, and 11 nM for E138K. It exhibits low cytotoxicity and a high selectivity index (CC50 = 21.95 μM, SI = 11478). Additionally, HIV-1inhibitor-79 shows antiviral activity against HIV-2, with an EC50 value of 6.14 μM, and effectively inhibits HIV-1 reverse transcriptase with an IC50 of 25 nM.Formula:C21H17N7OMolecular weight:383.41NF279
CAS:P2X1 antagonistFormula:C49H36N6Na6O23S6Purity:98%Color and Shape:SolidMolecular weight:1407.17Carbovir triphosphate
CAS:Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].Formula:C11H16N5O11P3Color and Shape:SolidMolecular weight:487.1912-Oxocalanolide A
12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.Formula:C22H24O5Color and Shape:SolidMolecular weight:368.429(2S,5S)-Censavudine
(2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.Formula:C12H12N2O4Color and Shape:SolidMolecular weight:248.23HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFormula:C26H24N6O2Color and Shape:SolidMolecular weight:452.51HIV gag peptide (197-205)
CAS:HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETIFormula:C45H81N11O14S2Purity:98%Color and Shape:SolidMolecular weight:1064.32[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92)
CAS:[(Cys(Bzl)84, Glu(OBzl)85)]CD4 (81-92) is a selective HIV-1 inhibitor that blocks the interaction between HIV-1 and CD4 molecules, thereby inhibiting viral infection and cell fusion. At a concentration of 25 μM, it can completely prevent fusion formation [1].Formula:C76H108N14O26SColor and Shape:SolidMolecular weight:1665.81JE-2178
CAS:JE-2178 is compound with high bioavailability .Formula:C35H51N5O6SColor and Shape:SolidMolecular weight:669.87HIV-1 inhibitor-81
HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.Formula:C32H44N2O8SColor and Shape:SolidMolecular weight:616.77F9170 TFA
F9170, an antiviral peptide derived from the HIV-1 envelope glycoprotein (amino acids 789-803), targets the LLP1 domain in the virus's envelope proteinFormula:C100H135N21O22·XCF3COOHMolecular weight:1983.30HIV p17 Gag (77-85)
CAS:Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.Formula:C44H72N10O15Purity:98%Color and Shape:SolidMolecular weight:981.1NNRT-IN-11
NNRT-IN-11 (14l) is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor, exhibiting EC50 values ranging from 6.50 to 52.9 nM against both wild-type (WT) and a range of HIV-1 mutant strains. NNRT-IN-11 demonstrates antiviral properties.Color and Shape:Odour SolidEnfuvirtide
CAS:Enfuvirtide is an anti-HIV-1 fusion peptide that inhibits HIV p24 antigen and Gag gene expression in macrophages.Formula:C204H301N51O64Purity:98%Color and Shape:White To Off-White Amorphous SolidMolecular weight:4491.95
![[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP2519.webp&w=3840&q=75)
