HIV Protease
HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.
Found 475 products for "HIV Protease".
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Aureothin
CAS:Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).Formula:C22H23NO6Color and Shape:SolidMolecular weight:397.42(-)-Rabdosiin
CAS:(-)-Rabdosiin, identified as a novel phenolic marker in Symphytum officinale L., exhibits antioxidant, neuroprotective, and anti-HIV activities [1].Formula:C36H30O16Color and Shape:SolidMolecular weight:718.61HIV protease-IN-1
CAS:HIV protease-IN-1 (compound 1·succinate), a potent non-peptidic inhibitor of HIV protease, is utilized for AIDS research [1].Formula:C39H40ClF7N10O7Color and Shape:SolidMolecular weight:929.24NNRT-IN-9
NNRT-IN-9 (Compound EG28) is a non-nucleoside reverse transcriptase inhibitor (NNRT). It demonstrates strong antiviral and resistance-fighting activity against wild-type (WT) and various clinically relevant mutant strains (E138K and K103N + Y181C) of HIV-1, with EC50 values of 55 nM, 67 nM, and 3910 nM, respectively. NNRT-IN-9 is applicable in acquired immunodeficiency syndrome (AIDS) research.Color and Shape:Odour SolidCys-TAT(47-57)
CAS:Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Formula:C67H124N34O14SPurity:98%Color and Shape:SolidMolecular weight:1661.99HIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Color and Shape:Odour SolidHIV gp120 (254-274)
CAS:HIV gp120 254-274, a conserved fragment of the envelope glycoprotein gp120 from the human immunodeficiency virus (HIV), displays immunosilent activity [1].Formula:C95H162N28O30SColor and Shape:SolidMolecular weight:2208.54FITC-LC-TAT (47-57)
FITC-labeled TAT (47-57) peptide enhances protein yields & solubility; TAT is a CPP.Formula:C91H141N35O19SColor and Shape:SolidMolecular weight:2061.38TAT-GluR23A Fusion Peptide
TAT-GluR23A Fusion Peptide is a bioactive peptide comprising the GluR23A sequence—residues 869 to 877 of GluR23Y with alanine replacing tyrosine—and an 11 aminoFormula:C97H173N43O26Color and Shape:SolidMolecular weight:2357.68HIV-1 protease-IN-13
HIV-1protease-IN-13 (compound 18d) is a potent inhibitor of HIV-1 protease (HIV-1protease) with an IC50 value of 0.54 nM. Additionally, HIV-1protease-IN-13 demonstrates effective activity against both HIV-1DRVRS (DRV resistant mutation) and HIV-1NL4_3 variants (wild-type).Formula:C29H36N2O7SColor and Shape:SolidMolecular weight:556.22432VIRIP
CAS:VIRIP (human α1-AT(353-372)) serves as an inhibitor of HIV-1. It impedes HIV-1 entry by binding to the gp41 fusion peptide, making it useful in virus research.Formula:C112H171N23O27SColor and Shape:SolidMolecular weight:2303.76mC46 peptide
mC46 (C46) peptide is a membrane-associated fusion peptide inhibitor that effectively impedes the replication and entry of HIV-1. Additionally, mC46 peptide can inhibit CCR5-tropic, CXCR4-tropic, and dual-tropic HIVs, as well as SIV and SHIV.Formula:C263H381N67O82SColor and Shape:SolidMolecular weight:5825.3Peptide T TFA
CAS:Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.Formula:C37H56F3N9O18Purity:98%Color and Shape:SolidMolecular weight:971.89Indoline
CAS:Indoline ,with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Indoline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C8H9NColor and Shape:Clear To Yellow LiquidMolecular weight:119.16IC-1k
IC-1k is an effective inhibitor of HIV-1, exhibiting anti-viral activity with EC50 values of 2.69 nM against HIV-1IIIB and 97.97 nM against HIV-2 ROD. Additionally, IC-1k has been noted to possess cytotoxic properties.Formula:C27H22F2N4O3SColor and Shape:SolidMolecular weight:520.55NF279
CAS:P2X1 antagonistFormula:C49H36N6Na6O23S6Purity:98%Color and Shape:SolidMolecular weight:1407.17Abacavir Carboxylate
CAS:Abacavir carboxylate, an inactive abacavir metabolite, forms via aldehyde intermediates bonding to valine in proteins.Formula:C14H16N6O2Color and Shape:SolidMolecular weight:300.322ELDKWA
CAS:ELDKWA, a highly conserved sequence of amino acids located on the ecto-domain of gp41, serves as the epitope for mAb 2F5, a neutralizing monoclonal antibodyFormula:C35H52N8O11Color and Shape:SolidMolecular weight:760.83Peptide T
CAS:Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.Formula:C35H55N9O16Purity:98%Color and Shape:SolidMolecular weight:857.86BNM-III-170
CAS:BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.Formula:C25H26ClF7N6O6Color and Shape:SolidMolecular weight:674.96MPG, HIV related
CAS:MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Formula:C126H201N35O33SPurity:98%Color and Shape:SolidMolecular weight:2766.22NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Formula:C32H31N9O3SColor and Shape:SolidMolecular weight:621.71Globotriaosylceramides (porcine)
CAS:Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.Formula:C60H113NO18Color and Shape:SolidMolecular weight:1136.553HIV-1 inhibitor-74
HIV-1inhibitor-74 (compound 10c) is a potent inhibitor of HIV-1, displaying an EC50 of 0.0047 µM against HIV-1IIIB. It exhibits cytotoxic properties and effectively inhibits the activity of WTHIV-1RT with an IC50 of 0.134 µM. Additionally, HIV-1inhibitor-74 demonstrates broad-spectrum anti-HIV-1 activity.Formula:C28H31N9O2SColor and Shape:SolidMolecular weight:557.67HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFormula:C23H40O5Purity:98%Color and Shape:SolidMolecular weight:396.56BMS-955176 TFA
CAS:GSK3532795: Oral HIV-1 maturation inhibitor, broad virus coverage, EC50: 15 nM, good preclinical pharmacokinetics.Formula:C44H64N2O8SPurity:98%Color and Shape:SolidMolecular weight:781.06Decanoyl-RVKR-CMK
CAS:Inhibits all seven proprotein convertases; stops proET-1 processing; hinders VGF secretion in PC12 cells.Formula:C34H66ClN11O5Purity:98%Color and Shape:SolidMolecular weight:744.42HIV-1 inhibitor-12
HIV-1 inhibitor-12: potent at inhibiting HIV-1 capsid protein polymerization with 9 nM IC50.Formula:C42H36ClF10N7O5S2Color and Shape:SolidMolecular weight:1008.35L 754394
CAS:L 754394 is an effective and specific inhibitor of the HIV-1 protease.Formula:C38H47N5O5Color and Shape:SolidMolecular weight:653.81Enfuvirtide
CAS:Enfuvirtide is an anti-HIV-1 fusion peptide that inhibits HIV p24 antigen and Gag gene expression in macrophages.Formula:C204H301N51O64Purity:98%Color and Shape:White SolidMolecular weight:4491.95Tipranavir
CAS:Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzymeFormula:C31H33F3N2O5SPurity:99.85%Color and Shape:White SolidMolecular weight:602.66Ref: TM-T4578
1mg69.00€5mg147.00€1mL*10mM (DMSO)192.00€10mg260.00€25mg580.00€50mg888.00€100mg1,485.00€200mg2,008.00€Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
CAS:Tenofovir-C3-O-C12 has a longer half-life, potent anti-HIV effects, and better pharmacokinetics than tenofovir.Formula:C29H55N6O5PSiColor and Shape:SolidMolecular weight:626.855HIV-1 inhibitor-80
HIV-1inhibitor-80 (compound M44) is an HIV-1 inhibitor with an EC50 of 5-148 nM. It demonstrates excellent metabolic stability and low cytotoxicity in human plasma and liver microsomes.Formula:C26H19N7OColor and Shape:SolidMolecular weight:445.475FITC-LC-TAT (47-57) acetate
FITC-LC-TAT (47-57) acetate is an FITC-labeled TAT peptide known as a cell-penetrating peptide (CPP). It enhances the yield and solubility of heterologous proteins.Color and Shape:Odour SolidTAT peptide
TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.Formula:C65H124N34O15Purity:98%Color and Shape:SolidMolecular weight:1621.91HIV-1 inhibitor-6
CAS:HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFormula:C14H10N4O4SPurity:99.33%Color and Shape:SolidMolecular weight:330.32Epicoccone B
CAS:Epicoccone B from C. globosum has DPPH scavenging (IC50=10.8μM) and α-glucosidase inhibition (IC50=27.3μM), also anti-HIV.Formula:C9H8O5Color and Shape:SolidMolecular weight:196.16PNU-142721
CAS:PNU-142721, reverse transcriptase inhibitor, is used to treat human immunodeficiency virus (HIV) infection.Formula:C13H11ClN4OSColor and Shape:SolidMolecular weight:306.77Lopinavir Metabolite M-1
CAS:Lopinavir Metabolite M-1, derived from Lopinavir, inhibits HIV protease (Ki=0.7 pM) and shows antiviral activity in vitro.Formula:C37H46N4O6Color and Shape:SolidMolecular weight:642.78Morin 3-O-β-D-glucopyranoside
CAS:Morin 3-O-β-D-glucopyranoside, natural flavonoid, antioxidant, anticancer. Inhibits reverse transcriptase and XO; exhibits anti-HIV activity.Formula:C21H20O12Color and Shape:Yellow SolidMolecular weight:464.38HIV-1 protease-IN-4
HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC & 67x C24 compared to atazanavir.Formula:C48H69N7O11Color and Shape:SolidMolecular weight:920.1(+)-Carbovir triphosphate
CAS:(+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.Formula:C11H16N5O11P3Color and Shape:SolidMolecular weight:487.19AL-470
CAS:AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFormula:C67H57N7O23Color and Shape:SolidMolecular weight:1328.2SDZ 283-910
CAS:SDZ 283-910 is used as a statine-derived inhibitor.Formula:C46H59N5O9Purity:98%Color and Shape:SolidMolecular weight:826.004Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Color and Shape:Odour SolidRef: TM-L1100
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireCTP518
CAS:CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.Formula:C38H52N6O7Purity:98%Color and Shape:SolidMolecular weight:719.95Elvucitabine
CAS:Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.Formula:C9H10FN3O3Color and Shape:SolidMolecular weight:227.19Pirmitegravir
CAS:Pirmitegravir (STP0404) is a potent ALLINI, blocks LEDGF/p75 site, shows antiviral action against HIV.Formula:C27H31ClN4O3Purity:99.79% - 99.79%Color and Shape:SolidMolecular weight:495.01HIV-1 inhibitor-65
HIV-1inhibitor-65 (compound 3c) is an inhibitor of HIV-1 with an EC50 of 2.9 nM and serves as an activator of protein kinase C (PKC). It effectively hinders syncytium formation with an EC50 of 7.0 nM, and prevents HIV-1 entry as well as the action of HIV-1 reverse transcriptase.Formula:C40H53FO6Color and Shape:SolidMolecular weight:648.38262
