Antibacterial

Antimycobacterial agent-6 (compound 25) effectively inhibits Mycobacterium tuberculosis, including wild-type and fluoroquinolone-resistant strains, by targeting

Dihydrotetrodecamycin, a fungal metabolite extracted from S. nashvillensis, exhibits antibacterial properties. It demonstrates activity against the fish-pathogenic bacterium P. piscicida.

Dodicin hydrochloride, an effective disinfectant, demonstrates broad antimicrobial activity [1].

PF 5081090 has a wide range of applications in life science related research.

Julifloricine is an alkaloid isolated from Prosopis juliflora that has antimicrobial activity.

Monocerin, from F. larvarum, combats E. coli, B. megaterium, M. violaceum, C. fusca; kills C. erythrocephala; hinders S. halepense root growth.

Altromycin D is a new pluramycin-like antibiotic.

Cefpirome: fourth-gen cephalosporin, broad-spectrum, inactivates penicillin-binding proteins in bacteria.

Brilacidin is a nonpeptidic anti-infective in a new class of defensin mimetics used for the research of eye infections.

8-Methylsulfinyloctyl isothiocyanate: antimicrobial, inhibits plant growth, impairs COX-2 inflammation in macrophages.

Alliacol B is an antibiotic with mild antibacterial and antifungal properties. It can inhibit DNA synthesis in Ehrlich ascites carcinoma cells.

Cephalexin: potent oral antibiotic, broad-spectrum against gram-positive/negative bacteria; treats pneumonia, strep throat, endocarditis.

Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.

Voxvoganan (LTX-109) trihydrochloride, a topical antimicrobial, demonstrates a high efficacy against S.

Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, potently inhibits methicillin-resistant Staphylococcus aureus (MRSA) [1].

Arylomycin A4 is a lipopeptide antibiotic (antibiotic) effective against Gram-positive bacteria.

"Benanomicin A, from Actinomycetes, is antifungal and antiviral, effective against pathogens like C. albicans and HIV-1 (MICs 3.13-50 μg/ml)."

Amustaline (S-303) dihydrochloride is a nucleic acid alkylator useful for inactivating pathogens in blood with red cells.

Antibacterial agent 136, an oxadiazolone antibiotic, highly potent against MRSA with MIC 50 at 0.8 μM.

Maximin 5, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal

Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins

Renierone is an antimicrobial metabolite isolated from the marine sponge, Reniera sp.

Betonicine, an l-alpha-amino acid, is in herbs, spices, pulses, and mainly urine.

Doxycycline hydrochloride (Hyclate) is a synthetic tetracycline derivative with similar antimicrobial activity.

Tetrahydrorhombifoline, a quinolizidine alkaloid found in the aerial parts of Genista vuralii A.

Hikizimycin is a potent anthelmintic and antibacterial natural product.

Linopristin is a streptogramin B class antibiotic. It is one of the components of the antibiotic combination NXL103.

A-54556B: Natural ADEP antibiotic from S. hawaiiensis, combats Gram-positive and anaerobic bacteria, including penicillin-resistant S. aureus.

Angustifoline HCl, from Lupinus angustifolius, has antimicrobial effects on S. aureus, B. subtilis, E. coli, P. aeruginosa, B. thuringiensis.

Vineomycin A1 (OS-4742 A1) is an antibiotic effective against Gram-positive bacteria, identified in *Streptomyces matensis* subsp. vineus. It has also demonstrated antitumor activity in mice and holds potential for research in skin fibrosis.

RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase [1] .

Murrayanol is a useful organic compound for research related to life sciences and the catalog number is T125851.

MRV03-070, acting as a biosynthetic precursor akin to precolibactin [1], is a colibactin-activating peptidase ClbP inhibitor with an inhibitory concentration (

(±)-Heraclenol, a coumarin derivative isolated from the fruits of Angelica lucida, exhibits antibacterial properties [1].

Lysobactin (katanosin B) is an antibiotic effective against S. aureus, S. pneumoniae, and blocks PG biosynthesis.

Antimicrobial agent-40 exhibits antibacterial activity against fungi, Gram-negative, and Gram-positive bacteria. It also shows anticancer properties, displaying significant cytotoxicity towards MCF-7 cells with an IC50 of 33.52 μM.

XMP-629, an endotoxin inhibitor, is used potentially for the treatment of impetigo and acne rosacea.

Aurein 5.2 is an antibiotic antimicrobial peptide [1].

Maximin H2, an antimicrobial peptide originating from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits inhibitory effects on a range

Cefazolin sodium pentahydrate: first-gen cephalosporin, treats bacterial infections, has anti-inflammatory properties, may reduce POCD.

Chlortetracycline, a broad-spectrum antibiotic, halts protein synthesis in Gram-positive/negative bacteria.

Cefotetan Sodium: a 2nd-gen cephamycin antibiotic effective against various aerobic/anaerobic, gram+/- bacteria, inhibits cell wall synthesis.

Cefozopran is a fourth-generation cephalosporin.

Sulfamerazine sodium salt is a sulfonamide antibacterial.

Vinclozolin (Ornalin) is a fungicide with anti-androgenic activity, commonly used in agriculture.

Erythromycin, a macrolide antibiotic, inhibits bacterial protein synthesis, effective against Streptococcus and Staphylococcus, and affects CYP3A4 metabolism.

Narasin inhibits dengue virus, treats coccidiosis without harm to cells, and induces cancer cell apoptosis.

Tylosin lactate: a vet macrolide antibiotic; broad vs. Gram-positive, limited on Gram-negative; from Streptomyces fradiae.

(R)-Eucomol, a flavonoid derivative, exhibits slight antibacterial properties and demonstrates cytotoxic activity against KB and P-388 cells [1].

Streptolydigin inhibits RNA synthesis by binding to RNA polymerase and does not inhibit eukaryotic RNA polymerases.

Faropenem daloxate (Faropenem medoxil) is useful for penem and antibiotics.

DS86760016 inhibits LeuRS; potent against MDR Gram-negative bacteria; IC50: E. coli 0.38μM, P. aeruginosa 0.62μM, A. baumannii 0.16μM.

Reveromycin D, from Streptomyces, blocks EGF in Balb/MK, halts KB/K562 growth, and shows pH-sensitive antifungal traits.

Antibacterialagent 271 is an antimicrobial compound that significantly inhibits Escherichia coli, with a minimum inhibitory concentration (MIC) of 2.2 μM. It disrupts bacterial membrane integrity, reducing metabolic activity. By binding to DNA grooves, it inhibits replication and induces reactive oxygen species (ROS) accumulation, leading to bacterial death. Antibacterialagent 271 shows considerable potential in combating bacterial infections.

Arylomycin A1 is a lipopeptide antibiotic (antibiotic) effective against Gram-positive bacteria.

17-hydroxy Venturicidin A: Streptomyces-derived macrolide with antibiotic and antifungal properties.

LBM-415 is a peptide deformylase (PDF) inhibitor.

Contezolid acefosamil sodium (MRX-4) is an oral antibiotic for drug-resistant Gram-positive cSSTIs, with low myelosuppression and MAOI risks.

Pazufloxacin (T-3761) is a broad-spectrum fluoroquinolone antibiotic effective against various infections, including strains resistant to other quinolones.

Arylomycin B6 is a lipoglycopeptide antibiotic (antibiotic) effective against Gram-positive bacteria.

Altromycin E is a new pluramycin-like antibiotic.

Terephthalonitrile exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa and can be used in related research in the field of life sciences.

Pyrocoll, from Streptomyces, stops various bacteria and cancer cells; active against P. falciparum, T. rhodesiense.

C8-HSL modulates Yersinia pestis virulence, gene expression, metabolism, and is used in cystic fibrosis research.

Tuberculosis inhibitor 9 (compound 3d), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against Mycobacterium tuberculosis and

Cis-β-Terpineol, a monoterpene derived from the aerial parts of Anthemis turcomanica, exhibits antibacterial activity as evidenced by studies on the stems,

Dicloxacillin, a β-Lactam antibiotic, targets beta-lactamase bacteria like Staphylococcus aureus, defeating penicillin resistance.

Ro 09-1428, a parenteral cephalosporin, has high antipseudomonal activity.

Maximin 15, an antimicrobial peptide originating from toad brain, exhibits activity against Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, with

Sirpefenicol (ZTS-00007928), a phenicol antibacterial for treating animal bacterial infections.

XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.

Flucloxacillin, an antibiotic, effectively combats both gram-positive and gram-negative bacteria [1] [2].

Gramicidin S (Gramicidin Soviet), a cationic cyclic peptide antibiotic, disrupts the membrane integrity of both Gram-positive and Gram-negative bacteria and

Tigecycline hydrate: broad-spectrum, glycylcycline antibiotic, bacteriostatic, inhibits protein synthesis, effective against resistant bacteria.

Polymyxin B2 is an antibiotic primarily utilized for resistant Gram-negative infections. It is derived from the bacterium Bacillus polymyxa.

Melimine, a hybrid antimicrobial peptide derived from Melittin and Protamine, exhibits broad-spectrum activity against various microorganisms, including

Agent 38 from patent WO2015063714A1 (C) serves as an antibacterial for scientific study.

SCH 38519, a fungal metabolite, inhibits thrombin, serotonin in platelets, and bacteria growth.

Compd 3j (Antibacterial agent 149) is a laccase inhibitor that exhibits potent fungicidal activity, particularly useful in researching rice sheath blight [1].

Bryostatin 1, a marine macrolide, permeates CNS and modulates PKC, with strong affinity for Munc13-1 (Ki: 8.07 nM and 0.45 nM).

Quinaldopeptin: a quinomycin antibiotic, combats various bacteria, cytotoxic to cells, aids in P388 leukemia mouse survival, intercalates DNA.

Aurein 3.1 is an antibiotic antimicrobial peptide, whereas Aurein 2.6 demonstrates activity against Gram-positive bacteria, exhibiting minimum inhibitory

Ledaborbactam etzadroxil (VNRX-7145) is an orally active inhibitor of Ambler class A, C, and D β-lactamase enzymes.

Samandarone is a major alkaloid from the European fire salamander (Salamandra salamandra terrestris).

Spectinamide-1599 is a combination partner for anti-tuberculosis therapy.

GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.

Deacetylnomilin is a useful organic compound for research related to life sciences. The catalog number is T125039 and the CAS number is 3264-90-2.

Talaromycesone A, from Talaromyces, fights S. epidermidis & MRSA (IC50: 3.7 & 5.48 μM), inhibits AChE (IC50: 7.49 μM).

Chartreusin is an antibiotic. It also has anticancer activity.

Desacetylcefotaxime, a Cefotaxime metabolite, has strong antimicrobial effects against various bacteria.

Clostomycin B2 is a bioactive chemical.

TP0586352 is a potent inhibitor of LpxC, exhibiting efficacy against carbapenem-resistant strains of Klebsiella pneumoniae without inducing cardiovascular risks

Oligomycin B is an antibiotic isolated from marine Streptomyces, is an eukaryotic ATP synthase inhibitor, induces apoptosis.

Azidocillin, a semi-synthetic oral β-lactam antibiotic, treats various bacterial infections including osteitis and septicemia.

Pseudomonic acid D is a topical antibiotic agent used against superficial skin infections such as impetigo or folliculitis.

Aurein 3.2 is an antimicrobial peptide with antibiotic properties and exhibits anticancer activity [1].