Antibacterial

Citromycetin, a fungal metabolite, has antibiotic effects on V. cholerae, S. flexneri, and S. aureus.

MF 961 is a quinolone bactericide. It exhibits MIC50 values in the range of 0-25 mg/L against E. coli, Klebsiella sp., Enterobacter sp., Citrobacter sp., and Shigella sp.

Impurity B in Cefpodoxime Proxetil, a broad-spectrum oral antibiotic, is a third-generation cephalosporin.

Orazamide may be useful to treat chronic hepatitis and various skin diseases.

Cellocidin inhibits gammaherpesvirus-related B-lymphoma growth via NF-κB and c-Myc pathways.

Desferriferribactin is a biogenetic precursor of pyoverdin.

Tibezonium iodide, an oropharyngeal disinfectant, possesses antibacterial properties that aid in preventing mouth infections [1].

Compound 5a: MICs of 25, 25, 50, 50 μg/mL vs. B. subtilis, S. aureus, P. aeruginosa, E. coli.

Antimycobacterial agent-10 (compound 5) is an inhibitor of DNA gyrase with an IC50 of 96 nM against Mycobacterium tuberculosis gyrase, demonstrating antibacterial properties.

Sperabillin C is a potent antibacterial antibiotic in vivo isolated from Pseudomonas fluorescens YK-437.

"Antibacterial Synergist 2 inhibits biofilms of S. enterica, S. aureus, P. aeruginosa, and C. albicans."

LtaS-IN-2 (compound 13), a derivative of LtaS-IN-1 [1], is an LTA synthesis inhibitor with antibacterial properties against S.

Hexylene glycol (Diolane), colorless liquid, is a chiral diol. It is an industrial compound produced from diacetone alcohol by hydrogenation.

Flambalactone is a degradation product formed by methanolysis of the antibiotic flambamycin.

VEGFR-2/InhA-IN-1, a dual inhibitor based on pyrazole, targets InhA and VEGFR, exhibiting both anti-tuberculosis and anti-angiogenic properties. It demonstrates effective antibacterial activity against the Mycobacterium tuberculosis H37Rv strain (MIC = 6.25 μg/mL) and significantly suppresses VEGFR-2 activity (IC 50 = 15.27 nM).

Flambamycin is an antibiotic isolated from Streptomyces hygroscopicus.

Janthinocin B is a novel macrocyclic peptide lactone antibiotic.

ω-azido-C6 Ceramide reduces membrane potential and exhibits antibacterial activity against Neisseria, with a minimum inhibitory concentration (MIC) of 2 µg/mL for N. meningitidis MC58 and N. gonorrhoeae FA1090.

Antibacterial agent 246 (compound A33) demonstrates a minimum inhibitory concentration (MIC) ranging from 0.5 to 4 μg/mL against 23 species of Gram-positive bacteria. When used in combination with Polymyxin E, it inhibits the growth of various Gram-negative bacteria, showing a partial inhibitory concentration index of 0.066.

Protactin, a new antibiotic metabolite, is a possible precursor of the actinomycins.

Chitinase, found in bacteria, fungi, animals, plants, is a glycosyl hydrolase that hydrolyzes chito-oligosaccharides.

Monensin sodium salt (Standard) is the standard substance of Monensin sodium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretion

Triclosan-methyl, derived from bactericidal triclosan, is used in toothpaste, shampoos, soaps, detergents, and cosmetics.

Kasugamycin hydrochloride (Standard) is the standard substance of Kasugamycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydrochloride was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.

Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.

Troleandomycin is a macrolide antibiotic and is similar to Erythromycin.

Acyclovir (Aciclovir) hydrochloride is an effective oral antiviral agent with potent anti-herpetic activity. It exhibits IC50 values of 0.85 μM for HSV-1 and 0.86 μM for HSV-2, indicating strong inhibitory effects against these strains. Additionally, Acyclovir hydrochloride induces cell cycle disturbances and apoptosis. This compound also prevents bacterial infections during induction therapy for acute leukemia.

Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.

Cefalexin hydrochloride is a cephalosporin antibiotic.

Sulfisoxazole (Standard) is the standard substance of Sulfisoxazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfisoxazole (Sulfafurazole) is a short-acting sulfonamide antibacterial with activity against a wide range of gram-negative and gram-positive organisms.Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A.

Avibactam free acid is a potent β-lactamase inhibitor exhibiting covalent and reversible properties, capable of inhibiting TEM-1, P99, and CTX-M-15.

Dibenzylideneacetone is a synthetic curcumin analog. It leads to apoptotic cell death in Leishmania donovani.

Sulfaclozine sodium: antibacterial, anticoccidial sulphonamide for poultry disease treatment.

G907 is an antagonist of the ATP-binding cassette (ABC) transporter protein MsbA with bactericidal activity. G907 inhibits MsbA in E. coli.

Quaternium 12, a bactericidal, virucidal, and fungicidal compound used in many products.

Metronidazole-d4 is a deuterium labeled compound isotopic tracing.Metronidazole is an antibiotic and antiprotozoal oral and BBB penetration anaerobic bacteria.

Iron (III) hexacyanoferrate (II) is a useful organic compound for research related to life sciences.

Deshydroxyethoxy ticagrelor (AR-C124910) is a metabolite of Ticagrelor that exhibits antibacterial activity against MRSA and possesses antiplatelet effects.

IMB-808 is an LXRα/β dual agonist that promotes ABCA1 expression and cholesterol efflux, used in atherosclerosis research.

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity and can be used to study urinary tract infections.

2-Cyclopentenone can inhibit the activity of HepG2 cells and has inhibitory activity against urease in Sporosarcina pasteurii.

OES2-0017 exhibits strong synergistic effects and growth inhibition in collaboration with polyamines within a low micromolar range. At low concentrations, OES2-0017 inhibits spermidine/spermine N1-acetyltransferase (SpeG) (IC50: 34.82 μM) and other polyamine detoxifying enzymes, while at higher concentrations, it disrupts bacterial membranes.

Pivampicillin, a pivalate ester analog of Ampicillin, is used to treat chronic obstructive pulmonary disease (COPD) in children and young adults.

EDTA disodium dihydrate chelates metals, inhibits proteases, and aids in protein purification; doesn't affect cellulase.

Oxacillin sodium monohydrate (Stapenor monohydrate) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.

N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL), a quorum-sensing signaling molecule synthesized by P. aeruginosa and specific B. cepacia complex strains [1][2], facilitates bacterial gene expression modulation in response to cell density escalation and triggers IL-8 production in 16HBE human bronchial epithelial cells [3].

Deuterium-labeled Sulfamethazine, an antimicrobial for treating animal diseases.

Tacrolimus-13C-d2 is the 13C and deuterated compound of Tacrolimus.