Antibacterial
Antibacterial inhibitors are compounds that target bacterial cells, inhibiting their growth or killing them outright. These inhibitors are essential in the development of treatments for bacterial infections and are widely used in research to study bacterial physiology, resistance mechanisms, and the efficacy of new antibacterial agents. At CymitQuimica, we offer a range of antibacterial inhibitors to support your research in microbiology, infectious diseases, and drug development.
Found 2949 products of "Antibacterial"
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844-TFM
<p>844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.</p>Formula:C24H25F3N4O2Color and Shape:SolidMolecular weight:458.48Antitubercular agent-29
<p>Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.</p>Formula:C20H12ClN3O5Color and Shape:SolidMolecular weight:409.78OPC-167832
CAS:<p>OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.</p>Formula:C21H20ClF3N2O4Color and Shape:SolidMolecular weight:456.847-Hydroxytropolone
CAS:<p>7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.</p>Formula:C7H6O3Color and Shape:SolidMolecular weight:138.12(4-Aminobenzoyl)-D-glutamic acid
CAS:<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Formula:C12H14N2O5Color and Shape:SolidMolecular weight:266.25Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Formula:C7H14N3NaO8SColor and Shape:SolidMolecular weight:323.26Antibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Formula:C16H23N3S2Color and Shape:SolidMolecular weight:321.5Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Formula:C18H23N5OSColor and Shape:SolidMolecular weight:357.47PF 03709270
CAS:<p>PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.</p>Formula:C19H27NO7S3Purity:98%Color and Shape:SolidMolecular weight:477.61Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formula:C31H44N2O6SColor and Shape:SolidMolecular weight:572.76Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Formula:C21H27N3SColor and Shape:SolidMolecular weight:353.52VEGFR-2/DHFR-IN-1
<p>Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.</p>Formula:C20H18ClNO4Color and Shape:SolidMolecular weight:371.81Elongation factor P-IN-2
<p>Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.</p>Formula:C16H35N3O2Color and Shape:SolidMolecular weight:301.47N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:<p>N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.</p>Formula:C17H19N5O5Color and Shape:SolidMolecular weight:373.363VEGFR-2/DHFR-IN-2
<p>VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.</p>Formula:C21H21NO4Color and Shape:SolidMolecular weight:351.4Rubropunctatin
CAS:<p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>Formula:C21H23NO4Color and Shape:SolidMolecular weight:353.41BM635 mesylate
<p>BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.</p>Formula:C26H33FN2O4SColor and Shape:SolidMolecular weight:488.61(E)-Cefodizime
CAS:<p>(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.</p>Formula:C20H20N6O7S4Color and Shape:SolidMolecular weight:584.669RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Formula:C22H26BrN5O4SColor and Shape:SolidMolecular weight:536.44Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Formula:C19H21N5O2SColor and Shape:SolidMolecular weight:383.47LpxC-IN-10
CAS:<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Formula:C30H31N5O3Color and Shape:SolidMolecular weight:509.6LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Formula:C22H19N3O2Color and Shape:SolidMolecular weight:357.41PqsR-IN-2
<p>PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.</p>Formula:C18H20ClN3OSColor and Shape:SolidMolecular weight:361.89MtMetAP1-IN-1
<p>MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.</p>Formula:C15H10BrN5O2SColor and Shape:SolidMolecular weight:404.24MtTMPK-IN-3
CAS:<p>MtTMPK-IN-3 inhibits Mycobacterium tuberculosis kinase with IC50 0.12μM, MIC 12.5μM on Mtb, cytotoxic EC50 12.5μM on MRC-5 cells.</p>Formula:C23H23Cl2N3O3Color and Shape:SolidMolecular weight:460.35FG-2101
CAS:<p>FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.</p>Formula:C30H32N5O6PColor and Shape:SolidMolecular weight:589.579Antibacterial agent 77
<p>Antibacterial agent 77 (compound 12) is an antibacterial agent [1].</p>Formula:C22H27N3OSColor and Shape:SolidMolecular weight:381.53GSK-3036656 free base
CAS:<p>GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.</p>Formula:C10H13BClNO4Color and Shape:SolidMolecular weight:257.48PptT-IN-3
<p>PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.</p>Formula:C16H27N5O3SColor and Shape:SolidMolecular weight:369.48Cefoxazole
CAS:<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formula:C21H18ClN3O7SColor and Shape:SolidMolecular weight:491.902RhlR antagonist 1
<p>RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.</p>Formula:C12H10F2OColor and Shape:SolidMolecular weight:208.2MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Formula:C26H35FN16O2Purity:98%Color and Shape:SolidMolecular weight:622.66MtTMPK-IN-7
<p>MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.</p>Formula:C27H29ClN6O3Color and Shape:SolidMolecular weight:521.01Antitubercular agent-11
<p>Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].</p>Formula:C16H15N3O4Color and Shape:SolidMolecular weight:313.31Antibacterial agent 279
CAS:<p>Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.</p>Formula:C9H11NO2SColor and Shape:SolidMolecular weight:197.25MtTMPK-IN-2
CAS:<p>MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).</p>Formula:C23H24ClN3O3Color and Shape:SolidMolecular weight:425.91Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Formula:C25H18N2O2SColor and Shape:SolidMolecular weight:410.49NFC nitro probe 1
CAS:<p>NFC nitro probe 1 (compound 18) is a chemical probe designed for the detection of Mtb, exhibiting high potency against both R-Mtb and NR-Mtb.</p>Formula:C19H19NO6Color and Shape:SolidMolecular weight:357.357Probenecid sodium
CAS:<p>Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.</p>Formula:C13H18NNaO4SColor and Shape:SolidMolecular weight:307.341Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formula:C25H24O9Color and Shape:SolidMolecular weight:468.453Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Formula:C24H33BrN2O2Color and Shape:SolidMolecular weight:461.44Antibacterial agent 262
CAS:<p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>Formula:C17H18F2N6O4S3Color and Shape:SolidMolecular weight:504.554Cephalosporin C
CAS:<p>Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.</p>Formula:C16H21N3O8SColor and Shape:SolidMolecular weight:415.418Colistin adjuvant-2
<p>Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].</p>Formula:C14H7Cl2F3N2OColor and Shape:SolidMolecular weight:347.12MurA-IN-6
CAS:<p>MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 of 26.63 μM. It exhibits antibacterial activity by inhibiting the function of MurA, a key protein essential for bacterial cell wall synthesis.</p>Formula:C22H17N3O3SColor and Shape:SolidMolecular weight:403.4544-Bromo A23187
CAS:<p>4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.</p>Formula:C29H36BrN3O6Purity:98%Color and Shape:SolidMolecular weight:602.52NBTIs-IN-5
CAS:<p>NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.</p>Formula:C24H25F3N4O2Color and Shape:SolidMolecular weight:458.48Deprodone
CAS:<p>Deprodone is an active compound that inhibits key processes such as bacterial cell wall synthesis by interacting with hydrolase and transferase proteins of methicillin-resistant Staphylococcus aureus (MRSA). It is applied in the research of MRSA infections, inflammatory skin diseases, intestinal disorders, and fatty acid metabolism disorders.</p>Formula:C21H28O4Color and Shape:SolidMolecular weight:344.44Diclosulam
CAS:<p>Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.</p>Formula:C13H10Cl2FN5O3SColor and Shape:SolidMolecular weight:406.22Anthelvencin A
CAS:<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formula:C19H25N9O3Color and Shape:SolidMolecular weight:427.46
