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S6 Kinase

S6 Kinase

S6 Kinase inhibitors are compounds that inhibit Ribosomal S6 Kinase (S6K), a downstream target of the mTOR signaling pathway. S6K plays a pivotal role in protein synthesis, cell growth, and cell cycle progression by phosphorylating the ribosomal protein S6. Inhibiting S6K is significant for studying its role in cellular growth, metabolism, and cancer. These inhibitors are also valuable in research on diseases linked to dysregulated mTOR signaling. At CymitQuimica, we offer S6 Kinase inhibitors to aid your research in cell growth, metabolism, and cancer biology.

Found 9 products of "S6 Kinase"

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  • SL 0101-1
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    SL 0101-1

    CAS:
    <p>SL0101: selective, reversible ATP-competitive RSK inhibitor, membrane-permeable, IC50=89nM, potent RSK1/2 inhibitor, Ki=1μM.</p>
    Formula:C25H24O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:516.45

    Ref: TM-T16896

  • S6K-18
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    S6K-18

    CAS:
    <p>S6K-18, a highly selective S6K1 inhibitor, inhibits S6K1 with IC50 of 52nM.</p>
    Formula:C17H18N4O3S
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:358.41

    Ref: TM-T22422

  • BI-D1870
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    BI-D1870

    CAS:
    <p>BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.</p>
    Formula:C19H23F2N5O2
    Purity:98.51% - 99.43%
    Color and Shape:Solid
    Molecular weight:391.42

    Ref: TM-T6171

  • LY-2584702 tosylate salt
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    LY-2584702 tosylate salt

    CAS:
    <p>LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment of cancer.</p>
    Formula:C28H27F4N7O3S
    Purity:98.5% - 98.51%
    Color and Shape:Solid
    Molecular weight:617.62

    Ref: TM-T1746

  • PF-4708671
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    PF-4708671

    CAS:
    <p>PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).</p>
    Formula:C19H21F3N6
    Purity:99.48% - 99.67%
    Color and Shape:Solid
    Molecular weight:390.41

    Ref: TM-T2002

  • LY-2584702 free base
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    LY-2584702 free base

    CAS:
    <p>LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).</p>
    Formula:C21H19F4N7
    Purity:98.72% - 99.51%
    Color and Shape:Solid
    Molecular weight:445.42

    Ref: TM-T6159

  • LJI308
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    LJI308

    CAS:
    LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
    Formula:C21H18F2N2O2
    Purity:99.73% - 99.87%
    Color and Shape:Solid
    Molecular weight:368.38

    Ref: TM-T6878

  • FMK
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    FMK

    CAS:
    <p>FMK 是一种不可逆的 RSK2 抑制剂，能够共价修饰 RSK 的 C 末端区域。</p>
    Formula:C18H19FN4O2
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:342.37

    Ref: TM-TQ0310

  • LY-2584702 hydrochloride
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    LY-2584702 hydrochloride

    CAS:
    <p>Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.</p>
    Formula:C21H20ClF4N7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:481.88

    Ref: TM-T11900