Organometallic Ligands
In this category, you will be able to find a large number of organometallic molecules used as ligands in biomolecules. These organometallic ligands can be used in organic chemistry and synthesis in the laboratory. They play a critical role in forming coordination complexes and catalyzing various chemical reactions. At CymitQuimica, we offer a diverse selection of high-quality organometallic ligands to support your research and industrial needs.
Subcategories of "Organometallic Ligands"
- Buchwald Ligands(22 products)
- DPEN(4 products)
- DPHEN(4 products)
- JOSIPHOS(4 products)
- Phosphine(497 products)
- Porphirines(75 products)
Found 2889 products of "Organometallic Ligands"
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Valiglurax
CAS:Potent and selective positive allosteric modulator (PAM) of metabotropic glutamate receptor mGlu4. Valiglurax is orally bioavailable and CNS-penetrant mGlu4 PAM in preclinical development for the Parkinson’s disease therapy and alleviation of the motor symptoms.Formula:C16H10F3N5Purity:Min. 95%Color and Shape:SolidMolecular weight:329.28 g/molMCC 950 sodium
CAS:Inhibitor of NLRP3 inflammasome and suppressor of the inflammatory cytokine IL-1β secretion. The compound was tested in diabetic mice and was shown to decrease the incidence of cardiac arrythmias, which are common secondary complications in diabetes mellitus. MCC 950 has potential to reverse diabetes-induced pathologies in cardiac electrophysiology.Formula:C20H23N2O5S·NaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:426.46 g/molLY 411575
CAS:Potent inhibitor of γ-secretase. LY 411575 inhibited production of amyloid β (Aβ) peptides with IC50 of 0.078 nM in vitro as well as decreased levels of Aβ40 and Aβ42 amyloids in brain of a mouse model for Alzheimer’s disease. In vitro studies confirmed that LY 411575 inhibited cleavage of Notch receptor at S3 site with IC50 of 0.39 nM, which blocked Notch activation and downstream signalling, leading to apoptosis in primary and immortalized Kaposi's sarcoma cells.Formula:C26H23F2N3O4Purity:Min. 95%Color and Shape:SolidMolecular weight:479.48 g/molPF 06409577
CAS:Potent agonist of a1β1γ1 5′-adenosine monophosphate-activated protein kinase (AMPK). It binds to the allosteric drug and metabolite (ADaM) site at the α- and β- subunit interface of AMPK. It has potential for the treatment of diabetic nephropathy. PF 06409577 reduces infections caused by flaviviruses, mediated by changes in the metabolism of lipids in host cells.
Formula:C19H16ClNO3Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:341.79 g/molAzumolene
CAS:Azumolene is a muscle relaxant drug, which is a synthetic derivative of dantrolene originating from hydantoin. The mode of action of Azumolene involves the inhibition of calcium ion release from the sarcoplasmic reticulum of skeletal muscle fibers. By impeding this release, Azumolene effectively reduces muscle contraction, thereby acting as a potent muscle relaxant.Formula:C13H9BrN4O3Purity:Min. 95%Color and Shape:PowderMolecular weight:349.14 g/molMitoxantrone hydrochloride
CAS:Inhibits DNA topoisomerase II; antineoplastic; immunomodulatory; antimicrobialFormula:C22H30Cl2N4O6Purity:Min. 97 Area-%Color and Shape:Dark Blue SolidMolecular weight:517.4 g/molUNC 4203
CAS:Potent and specific inhibitor of the tyrosine protein kinase Mer precursor (MERTK) with 38-fold selectivity over the FMS-like protein kinase FLT3. UNC 4203 inhibits MERTK with an IC50 value of 2.4 nM and shows favourable pharmacokinetic properties. In vivo experiments in mice showed that UNC 4203 dramatically decreased the phosphorylation of MERTK in bone marrow leukemia cells.Formula:C30H44N6OPurity:Min. 95%Color and Shape:Yellow PowderMolecular weight:504.71 g/molMelitracen hydrochloride
CAS:Tricyclic antidepressantFormula:C21H26NClPurity:Min. 95%Color and Shape:White PowderMolecular weight:327.89 g/molEtelcalcetide hydrochloride
CAS:Agonist of calcium sensing receptor CASR; calcimimetic agentFormula:C38H73N21O10S2·xHClPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:1084.71Interleukin-13 human
CAS:Interleukin-13 human is a recombinant cytokine, which is derived from the expression of the human IL-13 gene in suitable host systems, such as E. coli or mammalian cells. This cytokine belongs to the interleukin family and plays a pivotal role in the immune response by modulating inflammatory pathways. The mode of action of interleukin-13 involves binding to specific cell surface receptors, IL-13Rα1 and IL-13Rα2, which facilitates the activation of various intracellular signaling cascades, including the JAK/STAT pathway. This promotes the differentiation and proliferation of certain immune cells, influencing the production of IgE and contributing to the regulation of inflammatory responses.
Purity:Min. 95%Ponalrestat
CAS:Ponalrestat is an aldose reductase inhibitor, which is a synthetic compound developed for pharmacological purposes. It originates from chemical synthesis designed to target and inhibit the enzyme aldose reductase effectively. The mode of action involves the competitive inhibition of aldose reductase, an enzyme involved in the polyol pathway of glucose metabolism. By preventing the reduction of glucose to sorbitol, it reduces sorbitol accumulation associated with diabetic complications.Formula:C17H12BrFN2O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:391.19 g/molNilotinib HCl monohydrate - Bio-X ™
CAS:Nilotinib is a kinase inhibitor that is used for the treatment of Chronic Myeloid Leukemia (CML). This drug is also used for the treatment of CML that is resistant to imatinib. Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein. It also inhibits PDGFR and c-kit.
Formula:C28H22F3N7O•HCl•H2OPurity:Min. 95%Color and Shape:PowderMolecular weight:583.99 g/molTezacaftor
CAS:Potentiates cystic fibrosis transmembrane conductance regulator (CFTR)Formula:C26H27F3N2O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:520.5 g/molPrilocaine HCl - Bio-X ™
CAS:Prilocaine is a drug used as a local anaesthetic in dental procedures. It has been shown to reduce the incidence of pain caused. This drug is also a sodium channel blocker that blocks the influx of sodium into cells.Formula:C13H20N2O•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:256.77 g/molCYT 387
CAS:Inhibits JAK1 and JAK2 kinasesFormula:C23H22N6O2Purity:Min. 95%Color and Shape:PowderMolecular weight:414.46 g/molIsradipine
CAS:L-type calcium channel blockerFormula:C19H21N3O5Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:371.39 g/molMotesanib
CAS:Inhibitor of VEGFR, PDGR, c-Kit and Ret; inhibitor of angiogenesisFormula:C22H23N5OPurity:Min. 95%Molecular weight:373.45 g/molToceranib phosphate - Bio-X ™
CAS:Controlled ProductToceranib phosphate is a receptor tyrosine kinase inhibitor. Toceranib phosphate has been shown to be effective in the treatment of skin cancer and other types of cancer, including lung cancer and breast cancer. It is approved in the US as a treatment for canine mastocytoma (mast cell tumours).Formula:C22H25FN4O2·H3O4PPurity:Min. 95%Color and Shape:PowderMolecular weight:494.45 g/molFG 7142
CAS:Partial inverse agonist of benzodiazepine sites of the GABAA receptors with anxiogenic properties. FG 7142 is a pharmacological stressor which generates anxiety in humans and in experimental animals such as rhesus monkeys and rodents. FG 7142 also reduces food intake and frequency of feeding in male and female rats.Formula:C13H11N3OPurity:Min. 95%Color and Shape:Yellow PowderMolecular weight:225.25 g/molGNE 6776
CAS:Specific inhibitor of the ubiquitin specific protease-7 (USP7), which is a validated deubiquitinase of the E3 ubiquitin-protein ligase MDM2. The compound inhibits the USP7 deubiquitinase activity by binding to acidic amino acid residues important for the interaction with ubiquitin. Induces tumor cell death and enhances cytotoxicity of chemotherapeutic agents.Formula:C20H20N4O2Purity:Min. 95%Molecular weight:348.4 g/mol
