
Organometallic Ligands
Subcategories of "Organometallic Ligands"
- Buchwald Ligands(25 products)
- DPEN(4 products)
- DPHEN(4 products)
- JOSIPHOS(4 products)
- Phosphine(487 products)
- Porphirines(74 products)
Found 2781 products for "Organometallic Ligands".
Ponalrestat
CAS:Ponalrestat is an aldose reductase inhibitor, which is a synthetic compound developed for pharmacological purposes. It originates from chemical synthesis designed to target and inhibit the enzyme aldose reductase effectively. The mode of action involves the competitive inhibition of aldose reductase, an enzyme involved in the polyol pathway of glucose metabolism. By preventing the reduction of glucose to sorbitol, it reduces sorbitol accumulation associated with diabetic complications.Formula:C17H12BrFN2O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:391.19 g/molFM 19G11
CAS:Inhibitor of HIF1-α transcription factor and repressor of HIF1-α-regulated genes in adult and embryonic stem cell models as well as in tumoral cell lines. FM19G11 inhibits the expression of undifferentiating factors Oct4, Sox2, Nanog, and Tgf-α at transcriptional and protein level. FM 19G11 affects also epigenetic events by reducing histone acetylation and leading to repression of p300, a HIF-transcription activation co-factor.
Formula:C23H17N3O8Purity:Min. 95%Color and Shape:SolidMolecular weight:463.4 g/molFevipiprant
CAS:Prostaglandin D2 receptor antagonistFormula:C19H17F3N2O4SPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:426.41 g/molSNC 80
CAS:ÎŽ opioid receptor agonist; anti-nociceptive; anti-depressant
Formula:C28H39N3O2Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:449.63 g/molCYT 387
CAS:Inhibits JAK1 and JAK2 kinasesFormula:C23H22N6O2Purity:Min. 95%Color and Shape:PowderMolecular weight:414.46 g/molLY 2940094
CAS:Antagonist of nociceptin receptorsFormula:C22H23ClF2N4O2SPurity:Min. 95%Color and Shape:SolidMolecular weight:480.96 g/molIsradipine
CAS:L-type calcium channel blockerFormula:C19H21N3O5Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:371.39 g/molPF 06409577
CAS:Potent agonist of a1β1γ1 5′-adenosine monophosphate-activated protein kinase (AMPK). It binds to the allosteric drug and metabolite (ADaM) site at the α- and β- subunit interface of AMPK. It has potential for the treatment of diabetic nephropathy. PF 06409577 reduces infections caused by flaviviruses, mediated by changes in the metabolism of lipids in host cells.
Formula:C19H16ClNO3Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:341.79 g/molAceclofenac - Bio-X ™
CAS:Acecelofenac is a non-steroidal anti-inflammatory drug that is used in the treatment of osteoarthritis, arthritis, and ankylosing spondylitis. This drug is also a cyclooxygenase inhibitor and works by inhibiting this enzyme so that pain and inflammation is reduced.Formula:C16H13Cl2NO4Purity:Min. 95%Color and Shape:PowderMolecular weight:354.18 g/molRoflumilast - Bio-X ™
CAS:Roflumilast is a selective phosphodiesterase-4 inhibitor that is used for the treatment of exacerbations in patients with chronic obstructive pulmonary disease (COPD). It is also used to treat plaque psoriasis. This drug has anti-inflammatory and immunomodulatory effects as it aids in increasing levels of cAMP.
Formula:C17H14Cl2F2N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:403.21 g/molToceranib phosphate - Bio-X ™
CAS:Controlled ProductToceranib phosphate is a receptor tyrosine kinase inhibitor. Toceranib phosphate has been shown to be effective in the treatment of skin cancer and other types of cancer, including lung cancer and breast cancer. It is approved in the US as a treatment for canine mastocytoma (mast cell tumours).Formula:C22H25FN4O2·H3O4PPurity:Min. 95%Color and Shape:PowderMolecular weight:494.45 g/molDilevalol hydrochloride
CAS:Controlled ProductBeta-adrenoceptor antagonist; anti-hypertensiveFormula:C19H24N2O3·HClPurity:Min. 95%Color and Shape:SolidMolecular weight:364.87Mitoxantrone hydrochloride
CAS:Inhibits DNA topoisomerase II; antineoplastic; immunomodulatory; antimicrobialFormula:C22H30Cl2N4O6Purity:Min. 97 Area-%Color and Shape:Dark Blue SolidMolecular weight:517.4 g/molPadsevonil
CAS:Padsevonil is an investigational antiseizure medication, which is a synthetic pharmaceutical compound. It is derived from extensive medicinal chemistry research aiming to address complex seizure disorders resistant to conventional treatments. Padsevonil functions by exhibiting a dual mechanism of action. It binds to synaptic vesicle protein 2A (SV2A) with high affinity, similar to levetiracetam but with additional modulation of the benzodiazepine-sensitive gamma-aminobutyric acid-A (GABA-A) receptor. This combined activity potentiates its efficacy in stabilizing neuronal hyperactivity and dampening excitatory neurotransmission, providing a novel angle to tackle refractory seizures.Formula:C14H14ClF5N4O2SPurity:Min. 95%Molecular weight:432.8 g/molZotepine
CAS:Controlled ProductAntagonist of dopamine (D2), serotonin (5-HT2A) and histamine H1 receptorsFormula:C18H18ClNOSPurity:Min. 95%Color and Shape:PowderMolecular weight:331.86 g/molXMU MP 2
CAS:BRK tyrosine kinase (PTK6) inhibitor; anti-proliferative in breast cancer cells
Formula:C32H33F3N8O2Purity:Min. 95%Color and Shape:PowderMolecular weight:618.65 g/molRolapitant hydrochloride monohydrate
CAS:Neurokinin-1 (NK-1) receptor antagonistFormula:C25H27ClF6N2O2·H2OPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:554.95 g/molIdelalisib
CAS:Idelalisib is a pharmaceutical drug that functions as a PI3Kδ inhibitor, developed through synthetic chemical processes. Its mode of action involves selectively targeting and inhibiting phosphatidylinositol 3-kinase delta (PI3Kδ), a lipid kinase that plays a crucial role in the signaling pathways responsible for cell proliferation, survival, and differentiation. By inhibiting this enzyme, Idelalisib effectively impedes pathways that are often hyperactivated in certain hematologic malignancies, thereby exerting antitumor effects.Formula:C22H18FN7OPurity:Min. 95%Color and Shape:PowderMolecular weight:415.42 g/mol8-Deschloro-8-bromo-N-methyl desloratadine
CAS:Antagonist of platelet activating factorFormula:C20H21BrN2Purity:Min. 95%Color and Shape:PowderMolecular weight:369.3 g/molIvacaftor
CAS:Activates CFTR channelsFormula:C24H28N2O3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:392.49 g/mol
