Other Inhibitors

Dulozafone (F1933) has an anti- showed anticonvulsant activity in a brain amygdala ignition model and protected fully ignited rats from generalized seizures.

Trimethionine is a model peptide used in transport assays.

Dihydroxyaflavinine: A fungal toxin that non-competitively blocks GABAA channels and is toxic to armyworms and earworms.

Acetanilide, 2-(diethylamino)-4'-hydroxy-N-methyl- is a bioactive chemical.

Rhamnocitrin 3-galactoside is a natural product that can be used as a reference standard. The CAS number of Rhamnocitrin 3-galactoside is 99878-05-4.

Luseogliflozin hydrate: SGLT2 inhibitor, IC50 2.26 nM, oral, for type 2 diabetes research.

Swertianin 2-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside is a natural product for research related to life sciences.

Amino-PEG4-hydrazide-Boc is a PEGylation-based linker employed for the synthesis of PROTACs[1].

MI-2 (Menin-MLL Inhibitor) is an effective menin-MLL interaction inhibitor (IC50: 446 ± 28 nM).

PCTR2, an SPM derived from DHA oxidation, is found in resolving mouse exudate and human macrophages.

8-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione is a natural product for research related to life sciences.

Stephalonine P is a natural product for research related to life sciences. The catalog number is TN6292 and the CAS number is 2376309-57-6.

m-PEG13-Hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

7-Methoxy-1-naphthaleneacetic acid blocks auxin transport/action in plants, affecting Arabidopsis and maize.

RS-127445 maleate is a chemically selective antagonist with a high affinity for the 5-HT2B receptor, boasting an oral bioavailability and a pKi of 9.5.

RXFP3/4 agonist 1 is a relaxin family peptide 3/4 receptor (RXFP3/4) agonist(EC50s of 82/2 nM, respectivley).

Polypodine B 20,22-acetonide is a natural product for research related to life sciences. The catalog number is TN5305 and the CAS number is 159858-85-2.

Abbeokutone is a useful organic compound for research related to life sciences. The catalog number is T125620 and the CAS number is 16836-28-5.

Splenopentin (SP-5) is a synthetic immunomodulatory peptide that can reproduce the biological activity of TP and SP, respectively.

Azide-PEG4-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Methyl retinoate triggers inflammation, alters blood cells, may cause leukemia, and treats vitamin A deficiency issues.

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes. Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases. TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

Palmitodiolein is a triacylglycerol existed in vegetable oils.

N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based linker for PROTAC development.

3β,7β-Dihydroxy-25-methoxycucurbita-5,23-dien-19-al is a natural product for research related to life sciences.

Hexa-N-acetylchitohexaose boosts crop immunity, soybean health, and has antitumor effects.

L 628914 is a bioactive chemical.

PAR 4 (1-6) can be used for relevant research in the life sciences. Its product number is T36293 and CAS number is 225779-44-2.

2,3-Dimethylanthraquinone is an anthraquinone derivative widely used in biochemical experiments and drug synthesis research.

Tos-PEG9-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

6,6'-Di-O-sinapoylsucrose is a natural product for research related to life sciences. The catalog number is TN5838 and the CAS number is 1068661-35-7.

TAF10, a coactivator for RNA polymerase II, serves as a methyltransferase acceptor for 200+ reactions at 15 μM per vial.

N-Acetyldelectine is a natural product for research related to life sciences. The catalog number is TN6078 and the CAS number is 63596-61-2.

Diamyl sulfide is an agent of biochemical.

Xenthiorate hydrochloride is a biochemical.

IP receptor antagonist with pKi 8.3, no affinity for EP1-4/FP/TP; analgesic in rats, orally bioavailable.

meso-Hannokinol is a natural product for research related to life sciences. The catalog number is TN6358 and the CAS number is 79055-11-1.

Lipoaconitine is a natural product for research related to life sciences. The catalog number is TN6115 and the CAS number is 81941-14-2.

2-Mercaptoethyl decanoate is a biochemical.

Rat Pneumadin (PNM), a decapeptide, stimulates AVP release, exerting strong antidiuretic effects in animals with an active AVP system.

Jinflexin A is a natural product for research related to life sciences. The catalog number is TN5696 and the CAS number is 2055155-75-2.

Ferrimycin A1 is an iron-containing peptide antibiotic, and it acts as a competitive antagonist and acyl derivative of the microbial growth factor Ferribactin B.

m-PEG9-phosphonic acid ethyl ester, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].

The compound is extracted from Apium graveolens L.

Citromycin, an antibiotic, has weakly cytotoxic.

AR-H067637 is a fast-acting, reversible thrombin inhibitor with K(i) 2-4 nM; it also reduces clot-bound thrombin and platelet activation/aggregation.

Halomicin C is an ansamycin antibiotic effective against both Gram-positive and Gram-negative bacteria.

8,8''-Biskoenigine is a natural product for research related to life sciences. The catalog number is TN6197 and the CAS number is 477890-82-7.

Polymyxin E1, a peptide antibiotic and key component of the cationic lipopeptide antibiotic colistin, was initially extracted from B.

Impurity F of Calcipotriol is a impurity of Calcipotriol. Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

Wenchuanensin is a natural product that can be used as a reference standard. The CAS number of Wenchuanensin is 155961-85-6.

Dorsmanin I is a natural product for research related to life sciences. The catalog number is TN6351 and the CAS number is 329703-46-0.

Scrambled control peptide for use with TCS 183

14-O-Acetylsachaconitine is a natural product for research related to life sciences. The catalog number is TN6342 and the CAS number is 102719-98-2.

4-Nitrobenzoic acid (4Nitrobenzoic acid) is a pharmaceutical intermediate often found in the production of folic acid, DABA, PABA and dyes.

Avilamycin B is an orally active antibiotic isolated from Streptomyces viridochromogenes. Avilamycin B can be utilized in research concerning diseases related to intestinal bacteria.

The compound is extracted from Croton tiglium dried fruit.

m-PEG4-phosphonic acid ethyl ester is a linker for PROTACs, aiding in targeted protein degradation.

JNJ-39933673 is a bio-active chemical.

Pyruvate algebra stone (W-3395) is progesterone.

Methylionene is a natural product for research related to life sciences. The catalog number is TN4559 and the CAS number is 31197-54-3.

3-Indoleacrylic acid, a tryptophan metabolite by Peptostreptococcus, aids gut barrier and reduces inflammation.

Drechslerine A is a natural product from the metabolites of the algicolous fungus Drechslera dematioidea.

3-Sulfopropanoic acid, a major metabolite of treprostinil and its prodrug ALZ-801, is an endogenous molecule present in the cerebrospinal fluid (CSF) of AD

Capsianoside V methyl ester is a useful organic compound for research related to life sciences.

Marcellomycin is a glycoside and quinone antibiotic. It exhibits activity against Gram-positive bacteria, with particularly strong efficacy against streptococci.

EP4 receptor antagonist 3 from patent WO2010019796 A1 targets EP4 for research on pain, arthritis, and cancer.

(Z)-Lachnophyllum lactone is a natural product for research related to life sciences. The catalog number is TN5803 and the CAS number is 81122-95-4.

Hirudin (54-65; non-sulfated) is a desulfated anticoagulant fragment; it blocks fibrin clotting from bovine thrombin with an IC50 of 3.7μM.

Dipalmitoyl cystine is a bioactive chemical.

25-Epitorvoside D is a natural product for research related to life sciences. The catalog number is TN6322 and the CAS number is 1306729-49-6.

Epimedonin L is a natural product for research related to life sciences. The catalog number is TN5468 and the CAS number is 2215102-38-6.

HAE acetate is a 3-amino acid peptide composed of histidine, alanine and glutamate

Crocatone is a useful organic compound for research related to life sciences. The catalog number is T125426 and the CAS number is 19937-86-1.

m-PEG-Tos (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

WZ8040-hydroxyl, a WZ8040 derivative with extra hydroxyl, targets EGFRT790M mutations in cancer therapy.

5-Ethylindole is an indole derivative widely used in biochemical experiments and drug synthesis research.

Amino-PEG10-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

m-PEG12-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

7-Acetylintermedine is a hepatotoxic botanical pyrrolizidine alkaloid.

Ald-Ph-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Epiafzelechin-(2beta-O->7,4beta->8)-ent-epicatechin is a natural product that can be used as a reference standard. The CAS number of Epiafzelechin-(2beta-O->7,4beta->8)-ent-epicatechin is 135820-73-4.

Acid-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Solanapyrone C is a useful organic compound for research related to life sciences. The catalog number is T123989 and the CAS number is 88899-59-6.

Radicinin is used as a phytotoxic and antibiotic metabolite produced by some phytopathogenic fungi.

Isoleptospermone is a bioactive chemical.

2-(Octyloxy)acetic acid is a fungal metabolite that accumulates in the growth medium of Acinetobacter.

SC 29169 is a prostaglandin analog.

Chlorempenthrin is a synthetic pyrethroid insecticide.

Licorice acid is used for a zinc supplement in nutrition.

1-(3,4-Dihydroxyphenyl)-1-propanol, 3?,4?-Di-Me et is a useful organic compound for research related to life sciences and the catalog number is T130490.

CB 3988 is a bio-active chemical.

Danitracen is a biochemical.

5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine 2',3'-diacetate is an intermediate in the synthesis of capecitabine.

SST-02: simple one-step-synthesized cationic lipid for siRNA-LNPs with a 0.02 mg/kg ID50 in FVII model; safe at 3 mg/kg in rats.

Korepimedoside C (Epimedin I) - a flavonol glycoside from Epimedium koreanum, used in Chinese medicine for impotence and more.

S-Y048 is an OXE receptor antagonist that inhibits lung inflammation induced by aerosolized allergen challenge.

Lopinavir M-3/M-4 is a Lopinavir secondary metabolite.

Esculentoside E is a useful organic compound for research related to life sciences and the catalog number is T124459.