CymitQuimica logo
Cytoskeletal Signaling

Cytoskeletal Signaling

Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.

Found 1382 products of "Cytoskeletal Signaling"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Tubulin inhibitor 12

    CAS:
    <p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>
    Formula:C24H20N2O
    Color and Shape:Solid
    Molecular weight:352.43
  • BCR-ABL1-IN-1

    CAS:
    <p>BCR-ABL1-IN-1: potent, orally active ABL kinase inhibitor with high specificity, promising for CNS research.</p>
    Formula:C18H12F3N3O2
    Color and Shape:Solid
    Molecular weight:359.3
  • KY-04031

    CAS:
    <p>KY-04031 is an inhibitor of p21-activated kinase 4.</p>
    Formula:C21H20N8O
    Color and Shape:Solid
    Molecular weight:400.44
  • AFG210

    CAS:
    <p>AFG210 is a novel first-generation “type II” FLT3 inhibitor.</p>
    Formula:C19H14F3N3O2
    Color and Shape:Solid
    Molecular weight:373.33
  • BCR-ABL-IN-5

    CAS:
    <p>BCR-ABL-IN-5: Bcr-Abl kinase inhibitor, IC50: Bcr-AblWT 0.014 μM, Bcr-AblT315I 0.45 μM; anti-leukemia cell growth.</p>
    Formula:C25H21Cl2N5O2
    Color and Shape:Solid
    Molecular weight:494.37
  • Iso-Fludelone

    CAS:
    <p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>
    Formula:C27H36F3NO6
    Color and Shape:Solid
    Molecular weight:527.57
  • 10-DEBC hydrochloride

    CAS:
    <p>10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2].</p>
    Formula:C20H26Cl2N2O
    Color and Shape:Solid
    Molecular weight:381.34
  • DRP1i27

    CAS:
    <p>DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.</p>
    Formula:C20H26N6O
    Color and Shape:Solid
    Molecular weight:366.46
  • KY-04045

    CAS:
    <p>KY-04045 is a PAK4 inhibitor.</p>
    Formula:C13H14BrN5
    Color and Shape:Solid
    Molecular weight:320.19
  • NAMI-A

    CAS:
    <p>NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.</p>
    Formula:C8H15Cl4N4ORuS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:458.18
  • SSTC3

    CAS:
    <p>SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.</p>
    Formula:C23H17F3N4O3S2
    Purity:98.65% - 99.94%
    Color and Shape:Solid
    Molecular weight:518.53
  • CHMFL-ABL-053

    CAS:
    <p>CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.</p>
    Formula:C28H26F3N7O2
    Color and Shape:Solid
    Molecular weight:549.55
  • BuChE-IN-5

    CAS:
    <p>"BuChE-IN-5 is a potent inhibitor with an IC50 of 1.94 μM and shows promise for Alzheimer's research."</p>
    Formula:C25H35N3
    Color and Shape:Solid
    Molecular weight:377.57
  • Microtubule inhibitor 5

    CAS:
    <p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>
    Formula:C22H15FN2O4
    Color and Shape:Solid
    Molecular weight:390.36
  • AJH-836

    CAS:
    <p>AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of</p>
    Formula:C22H38O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:382.53
  • Tubulin inhibitor 27

    CAS:
    <p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>
    Formula:C21H19NO4
    Color and Shape:Solid
    Molecular weight:349.38
  • Tubulin polymerization-IN-10

    CAS:
    <p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>
    Formula:C18H21NO6S
    Color and Shape:Solid
    Molecular weight:379.43
  • HSP90-IN-22

    CAS:
    <p>HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in</p>
    Formula:C25H30N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:434.53
  • YM-1

    CAS:
    <p>YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.</p>
    Formula:C20H20ClN3OS2
    Color and Shape:Solid
    Molecular weight:417.98
  • Sibrafiban

    CAS:
    <p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>
    Formula:C20H28N4O6
    Color and Shape:Solid
    Molecular weight:420.46
  • Neuroinflammatory-IN-3

    CAS:
    <p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>
    Formula:C19H19ClO3
    Color and Shape:Solid
    Molecular weight:330.81
  • Tubulin polymerization-IN-36

    CAS:
    <p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>
    Formula:C18H18N2O3
    Color and Shape:Solid
    Molecular weight:310.35
  • Tubulin polymerization-IN-16

    CAS:
    <p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>
    Formula:C24H27N5O5
    Color and Shape:Solid
    Molecular weight:465.5
  • BCR-ABL-IN-6

    CAS:
    <p>BCR-ABL-IN-6, an imatinib derivative, inhibits Bcr-AblWT (4.6 nM IC50) and T315I (277 nM), for chronic myeloid leukemia study.</p>
    Formula:C27H22F3N5O2
    Color and Shape:Solid
    Molecular weight:505.49
  • Retaspimycin

    CAS:
    <p>Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).</p>
    Formula:C31H45N3O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.7
  • Tubulin polymerization-IN-15

    CAS:
    <p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>
    Formula:C18H17N3O4
    Color and Shape:Solid
    Molecular weight:339.35
  • Tubulin inhibitor 18

    CAS:
    <p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>
    Formula:C22H26O5
    Color and Shape:Solid
    Molecular weight:370.44
  • Tubulin polymerization-IN-18

    CAS:
    <p>Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.</p>
    Formula:C25H25NO6
    Color and Shape:Solid
    Molecular weight:435.47
  • GNF-1331

    CAS:
    <p>GNF-1331: potent, selective oral porcupine inhibitor; IC50=12 nM; targets aberrant Wnt signaling in cancers.</p>
    Formula:C20H20N6O2S2
    Color and Shape:Solid
    Molecular weight:440.54
  • Synstab A

    CAS:
    <p>Synstab A is a microtubule stabilizer.</p>
    Formula:C15H13BrCl3N3O3S
    Color and Shape:Solid
    Molecular weight:501.61
  • KUNB31

    CAS:
    <p>KUNB31 is a potent and selective inhibitor of Hsp90β.</p>
    Formula:C19H18N2O3
    Color and Shape:Solid
    Molecular weight:322.36
  • Microtubule inhibitor 7

    CAS:
    <p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>
    Formula:C25H19FN2O5
    Color and Shape:Solid
    Molecular weight:446.43
  • (S)-Dolaphenine hydrochloride

    CAS:
    <p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>
    Formula:C11H13ClN2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:240.75
  • Dihydrocytochalasin B

    CAS:
    <p>Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.</p>
    Formula:C29H39NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:481.62
  • MK-0668

    CAS:
    <p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>
    Formula:C31H30Cl2N6O6S
    Color and Shape:Solid
    Molecular weight:685.58
  • Tau tracer 1

    CAS:
    <p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>
    Formula:C34H23N5O2
    Color and Shape:Solid
    Molecular weight:533.591
  • Deox B 7,4

    CAS:
    <p>Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.</p>
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.33
  • SW02

    CAS:
    <p>SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).</p>
    Formula:C19H23BrN2O5
    Color and Shape:Solid
    Molecular weight:439.3
  • Tubulin polymerization-IN-30

    CAS:
    <p>Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.</p>
    Formula:C22H25N5O3
    Color and Shape:Solid
    Molecular weight:407.47
  • Tubulin inhibitor 29

    CAS:
    <p>Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.</p>
    Formula:C12H8F2O2S2
    Color and Shape:Solid
    Molecular weight:286.32
  • Microtubule inhibitor 6

    CAS:
    <p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>
    Formula:C24H19FN2O5
    Color and Shape:Solid
    Molecular weight:434.42
  • Tubulin inhibitor 31


    <p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>
    Formula:C22H19NO2
    Color and Shape:Solid
    Molecular weight:329.39
  • BCR-ABL-IN-1

    CAS:
    <p>BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.</p>
    Formula:C23H21F4N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:459.44
  • PD-173956

    CAS:
    <p>PD-173956 is an inhibitor of the Src family tyrosine kinases.</p>
    Formula:C20H13Cl2FN4O
    Color and Shape:Solid
    Molecular weight:415.25
  • Tubulin polymerization-IN-7

    CAS:
    <p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>
    Formula:C28H24N4O6S
    Color and Shape:Solid
    Molecular weight:544.58
  • PF-06651481-00

    CAS:
    <p>PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.</p>
    Formula:C26H29Cl2N5O3
    Purity:97.01%
    Color and Shape:Solid
    Molecular weight:530.45
  • β-glycosidase-IN-1

    CAS:
    <p>β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.</p>
    Formula:C13H23NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:273.33
  • TCS 2314

    CAS:
    <p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>
    Formula:C28H34N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:522.59
  • Anticancer agent 60

    CAS:
    <p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>
    Formula:C27H33N5O4S
    Color and Shape:Solid
    Molecular weight:523.65
  • Cevipabulin

    CAS:
    <p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>
    Formula:C18H18ClF5N6O
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:464.82
  • Mps-BAY2b

    CAS:
    <p>Mps-BAY2b is a novel MPS1 inhibitor.</p>
    Formula:C20H23N5O
    Color and Shape:Solid
    Molecular weight:349.43
  • Mps1-IN-4

    CAS:
    <p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>
    Formula:C26H31F3N6O2
    Color and Shape:Solid
    Molecular weight:516.56
  • AP 24149

    CAS:
    <p>AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.</p>
    Formula:C23H24N5OP
    Color and Shape:Solid
    Molecular weight:417.44
  • SB26019

    CAS:
    <p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>
    Formula:C24H20O4
    Color and Shape:Solid
    Molecular weight:372.41
  • YW1159

    CAS:
    <p>YW1159 is an inhibitor of Wnt signaling.</p>
    Formula:C19H14FN5O
    Color and Shape:Solid
    Molecular weight:347.35
  • AMXI-5001

    CAS:
    <p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>
    Formula:C25H20FN5O3
    Color and Shape:Solid
    Molecular weight:457.46
  • Tubulin polymerization-IN-21

    CAS:
    <p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>
    Formula:C30H29NO7
    Color and Shape:Solid
    Molecular weight:515.55
  • AM-9635

    CAS:
    <p>AM-9635: Potent PI3Kδ inhibitor, cellular IC50 4.2 nM, reduces IgG/IgM, well-tolerated, affects cell growth/division.</p>
    Formula:C19H14F2N8
    Color and Shape:Solid
    Molecular weight:392.36
  • Clathrin-IN-2

    CAS:
    <p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>
    Formula:C17H18Br2N2O
    Color and Shape:Solid
    Molecular weight:426.15
  • Tubulin inhibitor 20

    CAS:
    <p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>
    Formula:C19H18O4
    Color and Shape:Solid
    Molecular weight:310.34
  • BIIB028

    CAS:
    <p>BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.</p>
    Formula:C19H21ClN5O5P
    Color and Shape:Solid
    Molecular weight:465.83
  • Tubulin inhibitor 26

    CAS:
    <p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>
    Formula:C17H19N3O3
    Color and Shape:Solid
    Molecular weight:313.35
  • O-GlcNAcase-IN-4

    CAS:
    <p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>
    Formula:C16H22FN5O3S
    Color and Shape:Solid
    Molecular weight:383.44
  • BMS-587101

    CAS:
    <p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>
    Formula:C26H20Cl2N4O4S
    Color and Shape:Solid
    Molecular weight:555.43
  • Tubulin polymerization-IN-37

    CAS:
    <p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>
    Formula:C19H20N2O4
    Color and Shape:Solid
    Molecular weight:340.37
  • BOP sodium

    CAS:
    <p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>
    Formula:C25H29N3NaO7S
    Color and Shape:Solid
    Molecular weight:538.57
  • THK-5117

    CAS:
    <p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>
    Formula:C19H19FN2O2
    Color and Shape:Solid
    Molecular weight:326.36
  • Integrin modulator 1

    CAS:
    <p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>
    Formula:C13H14N2O4
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:262.26
  • XVA143

    CAS:
    <p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>
    Formula:C25H21Cl2N3O8
    Color and Shape:Solid
    Molecular weight:562.36
  • Debio 0617B

    CAS:
    <p>Debio 0617B inhibits kinases for AML stem cell treatment, targeting JAK, ABL, SRC, and STAT3-related tumours.</p>
    Formula:C28H23ClF3N7O2
    Color and Shape:Solid
    Molecular weight:581.98
  • Antitumor agent-68

    CAS:
    <p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>
    Formula:C17H11NO2
    Color and Shape:Solid
    Molecular weight:261.27
  • Antitumor agent-71

    CAS:
    <p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>
    Formula:C26H31N5O4S
    Color and Shape:Solid
    Molecular weight:509.62
  • BMS-358233

    CAS:
    <p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>
    Formula:C25H25ClN6O2S
    Color and Shape:Solid
    Molecular weight:509.02
  • PU24FCl

    CAS:
    <p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>
    Formula:C20H21ClFN5O3
    Color and Shape:Solid
    Molecular weight:433.86
  • KIF18A-IN-4

    CAS:
    <p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>
    Formula:C22H27N3O3S
    Color and Shape:Solid
    Molecular weight:413.53
  • Sabeluzole

    CAS:
    <p>Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.</p>
    Formula:C22H26FN3O2S
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:415.52
  • Valategrast hydrochloride

    CAS:
    <p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>
    Formula:C30H33Cl4N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:641.41
  • αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)


    <p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>
    Formula:C28H35F3N6O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:672.67
  • K-80003

    CAS:
    <p>K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.</p>
    Formula:C22H21FO2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:336.4
  • PS315

    CAS:
    <p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>
    Formula:C23H19ClO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:362.85
  • AKT-IN-2

    CAS:
    <p>AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).</p>
    Formula:C25H34F3N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.58
  • Balamapimod

    CAS:
    <p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>
    Formula:C30H32ClN7OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:574.14
  • GB1874

    CAS:
    <p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>
    Formula:C24H27N3O2S
    Color and Shape:Solid
    Molecular weight:421.56
  • AMP-PCP

    CAS:
    <p>AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.</p>
    Formula:C11H18N5O12P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.21
  • SR31527

    CAS:
    <p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability &amp; colony growth.</p>
    Formula:C15H14ClN3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.81
  • Eg5 Inhibitor V, trans-24

    CAS:
    <p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>
    Formula:C26H21N3O3
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:423.46
  • BBO-10203

    CAS:
    <p>BBO-10203 is an oral small molecule that disrupts PI3Kα-Ras interaction, inhibits Akt signaling selectively, and targets KRAS-mutant tumors.</p>
    Formula:C34H30F2N6O3S
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:640.7
  • ZINC194100678

    CAS:
    <p>ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.</p>
    Formula:C10H13N5O
    Purity:98.3%
    Color and Shape:Solid
    Molecular weight:219.24
  • TC-Mps1-12

    CAS:
    <p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>
    Formula:C17H20N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.38
  • KP-23172

    CAS:
    <p>KP-23172 is a inhibitor of PI3-K/Akt pathway.</p>
    Formula:C10H4N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:224.18
  • Tau-aggregation and neuroinflammation-IN-1

    CAS:
    <p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>
    Formula:C25H20N2O7
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:460.44
  • BCR-ABL-IN-7

    CAS:
    <p>BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.</p>
    Formula:C19H16FN3O3S
    Purity:98.28%
    Color and Shape:Solid
    Molecular weight:385.41
  • CpCDPK1/TgCDPK1-IN-1

    CAS:
    <p>CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.</p>
    Formula:C18H17N5
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:303.36
  • AM-5308

    CAS:
    <p>AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.</p>
    Formula:C26H35N5O5S
    Purity:98.06% - 99.58%
    Color and Shape:Solid
    Molecular weight:529.65
  • CGP60474

    CAS:
    <p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>
    Formula:C18H18ClN5O
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:355.82
  • Pentachloropseudilin

    CAS:
    <p>Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.</p>
    Formula:C10H4Cl5NO
    Purity:98.14%
    Color and Shape:Solid
    Molecular weight:331.41
  • Tyrphostin AG 568

    CAS:
    <p>Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.</p>
    Formula:C13H9N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:267.24
  • DHNQ

    CAS:
    <p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>
    Formula:C18H14N2O
    Color and Shape:Solid
    Molecular weight:274.32
  • NSC305787

    CAS:
    <p>NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.</p>
    Formula:C25H30Cl2N2O
    Purity:99.40%
    Color and Shape:Solid
    Molecular weight:445.42
  • Clathrin-IN-25

    CAS:
    <p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>
    Formula:C19H13KNO5S
    Color and Shape:Solid
    Molecular weight:406.47