Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formula:C24H27N3O4SPurity:97.81%Color and Shape:SolidMolecular weight:453.55Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Formula:C18H14N2O4Purity:95.85% - 99.22%Color and Shape:SolidMolecular weight:322.312',4'-DIHYDROXYCHALCONE
CAS:<p>2',4'-DIHYDROXYCHALCONE (2',4'-DHC) as a compound with Hsp90 inhibitory and antifungal effects</p>Formula:C15H12O3Purity:98.95%Color and Shape:SolidMolecular weight:240.25TB500
CAS:<p>TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.</p>Formula:C38H68N10O14Purity:99.51%Color and Shape:SolidMolecular weight:889.01Milnacipran ((1S-cis) hydrochloride)
CAS:<p>Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.</p>Formula:C15H23ClN2OPurity:99.81%Color and Shape:SolidMolecular weight:282.81VER-49009
CAS:<p>VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).</p>Formula:C19H18ClN3O4Purity:99.36% - 99.99%Color and Shape:SolidMolecular weight:387.82SC79
CAS:<p>SC79 is an AKT agonist with specificity and blood-brain barrier permeability.</p>Formula:C17H17ClN2O5Purity:98% - >99.99%Color and Shape:SolidMolecular weight:364.78Capivasertib
CAS:<p>Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.</p>Formula:C21H25ClN6O2Purity:97.59% - 99.6%Color and Shape:SolidMolecular weight:428.92TRC051384 HCl
CAS:<p>TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.</p>Formula:C25H32ClN5O4Purity:97.55%Color and Shape:SolidMolecular weight:502.01CK-869
CAS:<p>CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.</p>Formula:C17H16BrNO3SPurity:99.85%Color and Shape:SolidMolecular weight:394.28Vindesine sulfate
CAS:<p>Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.</p>Formula:C43H57N5O11SPurity:97.51%Color and Shape:Amorphous SolidMolecular weight:852GNF-7
CAS:<p>GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.</p>Formula:C28H24F3N7O2Purity:97.05% - 99.7%Color and Shape:SolidMolecular weight:547.53TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33AT7867
CAS:<p>AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC kinases.</p>Formula:C20H20ClN3Purity:99.63%Color and Shape:SolidMolecular weight:337.85AKT-IN-1
CAS:<p>AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 μM).</p>Formula:C22H21N3OPurity:98.63%Color and Shape:SolidMolecular weight:343.42Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Formula:C35H49N11O9S2·xC2H4O2Purity:99.7% - 99.87%Color and Shape:SolidMolecular weight:831.96 (free base)GNF-2
CAS:<p>GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.</p>Formula:C18H13F3N4O2Purity:98.17% - ≥95%Color and Shape:SolidMolecular weight:374.32Tianeptine sodium salt
CAS:<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Formula:C21H24ClN2NaO4SPurity:99.82%Color and Shape:SolidMolecular weight:458.93PRE-084 hydrochloride
CAS:<p>PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).</p>Formula:C19H28ClNO3Purity:99.54%Color and Shape:SolidMolecular weight:353.88Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Formula:C14H18ClN3O2SPurity:99.54% - ≥95%Color and Shape:White SolidMolecular weight:327.83Tetradecyltrimethylammonium bromide
CAS:<p>Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.</p>Formula:C17H38BrNPurity:99.80%Color and Shape:SolidMolecular weight:336.39roxifiban
CAS:<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Formula:C21H29N5O6Purity:98%Color and Shape:SolidMolecular weight:447.48Recilisib sodium
CAS:<p>Recilisib (ON 01210.Na) is a radioprotective agent altering cancer cell cycles and preventing radiation-induced apoptosis.</p>Formula:C16H13ClNaO4SColor and Shape:SolidMolecular weight:359.78IM-12
CAS:<p>IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.</p>Formula:C22H20FN3O2Purity:99.42% - >99.99%Color and Shape:SolidMolecular weight:377.41Tirbanibulin
CAS:<p>Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.</p>Formula:C26H29N3O3Purity:99.43% - 99.67%Color and Shape:SolidMolecular weight:431.53Pamidronate disodium pentahydrate
CAS:<p>Pamidronate disodium pentahydrate strengthens bones and prevents osteoporosis.</p>Formula:C3H21NNa2O12P2Purity:99.84%Color and Shape:White To Off-White Crystalline PowderMolecular weight:371.13NSC45586
CAS:<p>NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.</p>Formula:C20H18N6NaO3Purity:99.31%Color and Shape:SolidMolecular weight:413.4Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Formula:C31H43F6N9O12Purity:95.28% - ≥95%Color and Shape:SolidMolecular weight:847.72Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Formula:C18H16O8Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:360.31DDO-5936
CAS:<p>DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.</p>Formula:C25H29N5O4SPurity:99.81%Color and Shape:SolidMolecular weight:495.59FRAX486 HCL(1232030-35-1 free base)
<p>FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.</p>Formula:C25H24Cl3FN6OPurity:98.85% - 99.82%Color and Shape:SolidMolecular weight:549.86Bisindolylmaleimide V
CAS:<p>Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.</p>Formula:C21H15N3O2Purity:90%Color and Shape:Red SolidMolecular weight:341.36Defactinib
CAS:<p>Defactinib (VS-6063) is a second-generation inhibitor of FAK. Defactinib has potential antitumor activity. Cost-effective and quality-assured.</p>Formula:C20H21F3N8O3SPurity:98% - 99.71%Color and Shape:SolidMolecular weight:510.49Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Formula:C28H26Cl2N4O5Purity:99.26% - 99.72%Color and Shape:SolidMolecular weight:569.44Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Tau protein (592-597), Human TFA
<p>Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.</p>Formula:C36H63F3N10O11Purity:>99.99%Color and Shape:SolidMolecular weight:868.94Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Formula:C26H44NNaO6SPurity:98.23% - 99.45%Color and Shape:White To Off-White PowderMolecular weight:521.68Spastazoline
CAS:<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Formula:C20H30N8Purity:99.23%Color and Shape:SolidMolecular weight:382.51AZ3146
CAS:<p>AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.</p>Formula:C24H32N6O3Purity:97.84% - >99.99%Color and Shape:SolidMolecular weight:452.55Go 6983
CAS:<p>Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!</p>Formula:C26H26N4O3Purity:98.41% - 99.85%Color and Shape:SolidMolecular weight:442.51GW406108X(Z/E)
CAS:<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Formula:C20H11Cl2NO4Purity:98.23%Color and Shape:SolidMolecular weight:400.21Gap 27
CAS:<p>Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.</p>Formula:C60H101N15O17Purity:>99.99%Color and Shape:SolidMolecular weight:1304.53Leukadherin-1
CAS:<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Formula:C22H15NO4S2Purity:98.49% - 98.93%Color and Shape:SolidMolecular weight:421.49Olverembatinib dimesylate
CAS:<p>Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).</p>Formula:C29H27F3N6O·2CH4O3SPurity:97.66% - >99.99%Color and Shape:SolidMolecular weight:724.77ATM-3507 trihydrochloride
CAS:<p>ATM-3507 trihydrochloride, a potent inhibitor of tropomyosin, demonstrates inhibition concentration (IC50) values ranging from 3.83 to 6.84 μM across various</p>Formula:C37H49Cl3FN5O2Color and Shape:SolidMolecular weight:721.17KY-02327
CAS:<p>KY-02327: Stabilized KY-02061 analog, inhibits Dvl-CXXC5, activates Wnt/β-catenin, and promotes osteoblast differentiation.</p>Formula:C20H27N3O4Purity:97.04%Color and Shape:SolidMolecular weight:373.45TN-16
CAS:<p>TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)</p>Formula:C19H18N2O2Purity:99.54%Color and Shape:SolidMolecular weight:306.36α2β1 Integrin Ligand Peptide acetate
<p>α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.</p>Formula:C16H26N4O11Purity:98.46%Color and Shape:SolidMolecular weight:450.4
